Homer1 mediates CaSR-dependent activation of mTOR complex 2 and initiates a novel pathway for AKT-dependent β-catenin stabilization in osteoblasts

Localization of mTORC2 activity inside cells

(2017) Michael Ebner et al.   JOURNAL OF CELL BIOLOGY

The calcium-sensing receptor in bone—mechanistic and therapeutic insights

(2015) David Goltzman et al.   Nature Reviews Endocrinology

Roles of the calcium sensing receptor in the central nervous system

(2013) Martial Ruat et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation

(2013) Emel Esen et al.   Cell Metabolism

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

XPLN is an endogenous inhibitor of mTORC2

(2013) N. Khanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Vitamin D Receptor and ERp57 in Photoprotection by 1α,25-Dihydroxyvitamin D3

(2012) Vanessa B. Sequeira et al.   MOLECULAR ENDOCRINOLOGY

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An Akt-dependent Increase in Canonical Wnt Signaling and a Decrease in Sclerostin Protein Levels Are Involved in Strontium Ranelate-induced Osteogenic Effects in Human Osteoblasts

(2011) Mark S. Rybchyn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoblast extracellular Ca2+-sensing receptor regulates bone development, mineralization, and turnover

(2011) Melita M Dvorak-Ewell et al.   JOURNAL OF BONE AND MINERAL RESEARCH

GPCR Interacting Proteins (GIPs) in the Nervous System: Roles in Physiology and Pathologies

(2010) Joël Bockaert et al.   Annual Review of Pharmacology and Toxicology

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS

Increased Receptor Stimulation Elicits Differential Calcium-sensing ReceptorT888Dephosphorylation

(2010) Wanda D. McCormick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of chondroitin sulfate glycosaminoglycans in mineralizing osteoblast-like cells: Effects of hormonal manipulation

(2010) M. Slater et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoclastogenic activity and RANKL expression are inhibited in osteoblastic cells expressing constitutively active Gα12 or constitutively active RhoA

(2010) Jun Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

What old means to bone

(2010) Stavros C. Manolagas et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Osteoblasts play key roles in the mechanisms of action of strontium ranelate

(2009) TC Brennan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Wnt signaling in bone metabolism

(2009) Takuo Kubota et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Homer Interactions Are Necessary for Metabotropic Glutamate Receptor-Induced Long-Term Depression and Translational Activation

(2008) J. A. Ronesi et al.   JOURNAL OF NEUROSCIENCE

The Extracellular Calcium-Sensing Receptor (CaSR) Is a Critical Modulator of Skeletal Development

(2008) W. Chang et al.   Science Signaling