An Akt-dependent Increase in Canonical Wnt Signaling and a Decrease in Sclerostin Protein Levels Are Involved in Strontium Ranelate-induced Osteogenic Effects in Human Osteoblasts

Essential Role of Nuclear Factor of Activated T Cells (NFAT)-mediated Wnt Signaling in Osteoblast Differentiation Induced by Strontium Ranelate

(2010) Olivia Fromigué et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of chondroitin sulfate glycosaminoglycans in mineralizing osteoblast-like cells: Effects of hormonal manipulation

(2010) M. Slater et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Long-term treatment of postmenopausal osteoporosis with strontium ranelate: Results at 8 years

(2009) J.Y. Reginster et al.   BONE

Osteoblasts play key roles in the mechanisms of action of strontium ranelate

(2009) TC Brennan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Characterization of the Structural Features and Interactions of Sclerostin

(2009) Vaclav Veverka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt signaling in bone metabolism

(2009) Takuo Kubota et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β-Catenin Signaling

(2009) Chuwen Lin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Selective Signaling by Akt2 Promotes Bone Morphogenetic Protein 2-Mediated Osteoblast Differentiation

(2009) A. Mukherjee et al.   MOLECULAR AND CELLULAR BIOLOGY

In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization

(2009) G. Boivin et al.   OSTEOPOROSIS INTERNATIONAL

Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis

(2009) P. J. Meunier et al.   OSTEOPOROSIS INTERNATIONAL

Lrp4, a Novel Receptor for Dickkopf 1 and Sclerostin, Is Expressed by Osteoblasts and Regulates Bone Growth and Turnover In Vivo

(2009) Hong Y. Choi et al.   PLoS One

Correlation of mRNA and protein levels: Cell type-specific gene expression of cluster designation antigens in the prostate

(2008) Laura E Pascal et al.   BMC GENOMICS

Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response

(2008) G. J. Atkins et al.   OSTEOPOROSIS INTERNATIONAL

Dual effect of strontium ranelate: Stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro

(2007) Edith Bonnelye et al.   BONE