Transforming growth factor β1 alters the 3′-UTR of mRNA to promote lung fibrosis

Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation

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Suppression of cleavage factor Im 25 promotes the proliferation of lung cancer cells through alternative polyadenylation

(2018) Jingjing Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

(2018) Justin Brumbaugh et al.   CELL

Extracellular matrix as a driver of progressive fibrosis

(2018) Jeremy Herrera et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting TGF-β signaling for the treatment of fibrosis

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Extracellular matrix: The driving force of mammalian diseases

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Therapeutic approaches to control tissue repair and fibrosis: Extracellular matrix as a game changer

(2018) Mariëlle Walraven et al.   MATRIX BIOLOGY

OUP accepted manuscript

(2018)   NUCLEIC ACIDS RESEARCH

NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression

(2018) Sheng Tan et al.   ONCOGENE

Alternative polyadenylation in the regulation and dysregulation of gene expression

(2018) Rachael Emily Turner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

CFIm25 inhibits hepatocellular carcinoma metastasis by suppressing the p38 and JNK/c-Jun signaling pathways

(2018) Yunwu Wang et al.   Oncotarget

The Anti-fibrotic Effect of Adenosine A2B Receptor Antagonism in a Mouse Model of Dermal Fibrosis

(2018) Harry Karmouty-Quintana et al.   Arthritis & Rheumatology

Comprehensive Characterization of Alternative Polyadenylation in Human Cancer

(2017) Yu Xiang et al.   JNCI-Journal of the National Cancer Institute

Comprehensive Characterization of Alternative Polyadenylation in Human Cancer

(2017) Yu Xiang et al.   JNCI-Journal of the National Cancer Institute

Alternative Polyadenylation: Methods, Findings, and Impacts

(2017) Wei Chen et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Cigarette Smoke Disrupted Lung Endothelial Barrier Integrity and Increased Susceptibility to Acute Lung Injury via Histone Deacetylase 6

(2016) Diana Borgas et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mechanistic Target of Rapamycin Complex 1 (mTORC1) and mTORC2 as Key Signaling Intermediates in Mesenchymal Cell Activation

(2016) Natalie M. Walker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibroblast growth factors and pulmonary fibrosis: it's more complex than it sounds

(2016) Kevin K Kim et al.   JOURNAL OF PATHOLOGY

Alternative Polyadenylation of mRNAs: 3′-Untranslated Region Matters in Gene Expression

(2016)   MOLECULES AND CELLS

Nintedanib in patients with idiopathic pulmonary fibrosis: Combined evidence from the TOMORROW and INPULSIS® trials

(2016) Luca Richeldi et al.   RESPIRATORY MEDICINE

Evolution and Biological Roles of Alternative 3′UTRs

(2016) Christine Mayr   TRENDS IN CELL BIOLOGY

Nintedanib and Pirfenidone. New Antifibrotic Treatments Indicated for Idiopathic Pulmonary Fibrosis Offer Hopes and Raises Questions

(2015) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis

(2015) Lutz Wollin et al.   EUROPEAN RESPIRATORY JOURNAL

Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis

(2015) Jianzhong Li et al.   KIDNEY INTERNATIONAL

NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation

(2015) Vincenzo A Gennarino et al.   eLife

Update on therapeutic management of idiopathic pulmonary fibrosis

(2015) Paolo Spagnolo et al.   Therapeutics and Clinical Risk Management

Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis

(2014) Hong Xia et al.   AMERICAN JOURNAL OF PATHOLOGY

Blockade of IL-6TransSignaling Attenuates Pulmonary Fibrosis

(2014) Thanh-Thuy T. Le et al.   JOURNAL OF IMMUNOLOGY

CFIm25 links alternative polyadenylation to glioblastoma tumour suppression

(2014) Chioniso P. Masamha et al.   NATURE

A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

(2014) Talmadge E. King et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Critical Role for the mTORC2 Pathway in Lung Fibrosis

(2014) Wenteh Chang et al.   PLoS One

The Role of Extracellular Matrix Quality in Pulmonary Fibrosis

(2014) Jacob Hull Kristensen et al.   RESPIRATION

Mechanism of actin filament pointed-end capping by tropomodulin

(2014) J. N. Rao et al.   SCIENCE

Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types

(2014) Zheng Xia et al.   Nature Communications

Transforming Growth Factor β-regulated MicroRNA-29a Promotes Angiogenesis through Targeting the Phosphatase and Tensin Homolog in Endothelium

(2013) Jun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF-β/Smad2/3 Signaling Directly Regulates Several miRNAs in Mouse ES Cells and Early Embryos

(2013) Nicholas Redshaw et al.   PLoS One

Alternative polyadenylation: New insights from global analyses

(2012) Y. Shi   RNA

TGF-β signaling in fibrosis

(2011) Anna Biernacka et al.   GROWTH FACTORS

Integrating mechanisms of pulmonary fibrosis

(2011) Thomas A. Wynn   JOURNAL OF EXPERIMENTAL MEDICINE

Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain

(2011) William T. Senapedis et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanisms and Consequences of Alternative Polyadenylation

(2011) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

Cistrome: an integrative platform for transcriptional regulation studies

(2011) Tao Liu et al.   GENOME BIOLOGY

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

MicroRNA-155 Is Regulated by the Transforming Growth Factor  /Smad Pathway and Contributes to Epithelial Cell Plasticity by Targeting RhoA

(2008) W. Kong et al.   MOLECULAR AND CELLULAR BIOLOGY