A genetic mouse model of severe iron deficiency anemia reveals tissue-specific transcriptional stress responses and cardiac remodeling

SMAD family member 3 (SMAD3) and SMAD4 repress HIF2a-dependent iron-regulatory genes

(2019) Xiaoya Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anemia and iron deficiency in heart failure: a review of echocardiographic features

(2019) Mario Sutil-Vega et al.   ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES

Arterial blood sampling in male CD-1 and C57BL/6J mice with 1% isoflurane is similar to awake mice

(2018) Ashley M. Loeven et al.   JOURNAL OF APPLIED PHYSIOLOGY

Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload

(2018) Andrew J. Schwartz et al.   JOURNAL OF CLINICAL INVESTIGATION

Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology

(2016) Nihal Bakeer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An essential cell-autonomous role for hepcidin in cardiac iron homeostasis

(2016) Samira Lakhal-Littleton et al.   eLife

Use of a Low-flow Digital Anesthesia System for Mice and Rats

(2016) Amelia R. Adelsperger et al.   Jove-Journal of Visualized Experiments

Ironing out Ferroportin

(2015) Hal Drakesmith et al.   Cell Metabolism

Iron-Deficiency Anemia

(2015) Clara Camaschella   NEW ENGLAND JOURNAL OF MEDICINE

Maternal intestinal HIF-2α is necessary for sensing iron demands of lactation in mice

(2015) Sadeesh K. Ramakrishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis

(2015) Alan C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart

(2015) Wenjing Xu et al.   Cell Reports

Hypoxia-Inducible Factors Link Iron Homeostasis and Erythropoiesis

(2014) Yatrik M. Shah et al.   GASTROENTEROLOGY

Iron-Refractory Iron Deficiency Anemia (IRIDA)

(2014) Matthew M. Heeney et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2  mRNA translation

(2013) N. Wilkinson et al.   BLOOD

The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption

(2013) Sheila A. Anderson et al.   Cell Metabolism

Endothelial PAS Domain Protein 1 Activates the Inflammatory Response in the Intestinal Epithelium to Promote Colitis in Mice

(2013) Xiang Xue et al.   GASTROENTEROLOGY

Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice

(2013) Shuling Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P

(2012) S. N. Zolov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice

(2011) Matthew Taylor et al.   GASTROENTEROLOGY

Intestinal Hypoxia-inducible Factor-2α (HIF-2α) Is Critical for Efficient Erythropoiesis

(2011) Erik R. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How does PKMζ maintain long-term memory?

(2010) Todd C. Sacktor   NATURE REVIEWS NEUROSCIENCE

Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

(2009) Yatrik M. Shah et al.   Cell Metabolism

HIF-2α, but not HIF-1α, promotes iron absorption in mice

(2009) Maria Mastrogiannaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

(2008) Karin E Finberg et al.   NATURE GENETICS

Worldwide prevalence of anaemia, WHO Vitamin and Mineral Nutrition Information System, 1993–2005

(2008) Erin McLean et al.   PUBLIC HEALTH NUTRITION