Surprise! A hidden B12 cofactor catalyzes a radical methylation

Capturing Intermediates in the Reaction Catalyzed by NosN, a Class C Radical S-Adenosylmethionine Methylase Involved in the Biosynthesis of the Nosiheptide Side Ring System

(2019) Bo Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Methanogenesis marker protein 10 (Mmp10) from Methanosarcina acetivorans is a radical S-adenosylmethionine methylase that unexpectedly requires cobalamin

(2019) Matthew I. Radle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a unique Radical SAM methyltransferase required for the sp3-C-methylation of an arginine residue of methyl-coenzyme M reductase

(2018) Darja Deobald et al.   Scientific Reports

The B12-Radical SAM Enzyme PoyC Catalyzes Valine Cβ-Methylation during Polytheonamide Biosynthesis

(2016) Aubérie Parent et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein Methyltransferases: A Distinct, Diverse, and Dynamic Family of Enzymes

(2015) P. Ann Boriack-Sjodin et al.   BIOCHEMISTRY

Mechanistic Diversity of RadicalS-Adenosylmethionine (SAM)-dependent Methylation

(2014) Matthew R. Bauerle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Radical-Mediated Enzymatic Methylation: A Tale of Two SAMS

(2011) Qi Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH