Duration of pretomanid/moxifloxacin/pyrazinamide therapy compared with standard therapy based on time-to-extinction mathematics

Drug Penetration Gradients Associated with Acquired Drug Resistance in Tuberculosis Patients

(2018) Keertan Dheda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

OUP accepted manuscript

(2018)   CLINICAL INFECTIOUS DISEASES

Ceftazidime-avibactam has potent sterilizing activity against highly drug-resistant tuberculosis

(2017) Devyani Deshpande et al.   Science Advances

A Faropenem, Linezolid, and Moxifloxacin Regimen for Both Drug-Susceptible and Multidrug-Resistant Tuberculosis in Children: FLAME Path on the Milky Way

(2016) Devyani Deshpande et al.   CLINICAL INFECTIOUS DISEASES

Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo

(2016) Devyani Deshpande et al.   CLINICAL INFECTIOUS DISEASES

A Long-term Co-perfused Disseminated Tuberculosis-3D Liver Hollow Fiber Model for Both Drug Efficacy and Hepatotoxicity in Babies

(2016) Shashikant Srivastava et al.   EBioMedicine

Systematic Analysis of Hollow Fiber Model of Tuberculosis Experiments

(2015) Jotam G. Pasipanodya et al.   CLINICAL INFECTIOUS DISEASES

Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis

(2015) Derek J. Sloan et al.   CLINICAL INFECTIOUS DISEASES

Forecasting Accuracy of the Hollow Fiber Model of Tuberculosis for Clinical Therapeutic Outcomes

(2015) Tawanda Gumbo et al.   CLINICAL INFECTIOUS DISEASES

Correlations Between the Hollow Fiber Model of Tuberculosis and Therapeutic Events in Tuberculosis Patients: Learn and Confirm

(2015) Tawanda Gumbo et al.   CLINICAL INFECTIOUS DISEASES

Nonclinical Models for Antituberculosis Drug Development: A Landscape Analysis

(2015) Tawanda Gumbo et al.   JOURNAL OF INFECTIOUS DISEASES

Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label, partly randomised trial in patients with drug-susceptible or drug-resistant pulmonary tuberculosis

(2015) Rodney Dawson et al.   LANCET

The association between sterilizing activity and drug distribution into tuberculosis lesions

(2015) Brendan Prideaux et al.   NATURE MEDICINE

PA-824 is as effective as isoniazid against latent tuberculosis infection in C3HeB/FeJ mice

(2014) Noton K. Dutta et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Potent Rifamycin-Sparing Regimen Cures Guinea Pig Tuberculosis as Rapidly as the Standard Regimen

(2013) Noton K. Dutta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activities of Drug Combinations against Mycobacterium tuberculosis Grown in Aerobic and Hypoxic Acidic Conditions

(2013) Giovanni Piccaro et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

14-day bactericidal activity of PA-824, bedaquiline, pyrazinamide, and moxifloxacin combinations: a randomised trial

(2012) Andreas H Diacon et al.   LANCET

Pharmacokinetic Mismatch Does Not Lead to Emergence of Isoniazid- or Rifampin-Resistant Mycobacterium tuberculosis but to Better Antimicrobial Effect: a New Paradigm for Antituberculosis Drug Scheduling

(2011) Shashikant Srivastava et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of moxifloxacin for the treatment of tuberculosis: 3 years of experience

(2011) A. D. Pranger et al.   EUROPEAN RESPIRATORY JOURNAL

Multidrug-Resistant Tuberculosis Not Due to Noncompliance but to Between-Patient Pharmacokinetic Variability

(2011) Shashikant Srivastava et al.   JOURNAL OF INFECTIOUS DISEASES

Early Bactericidal Activity and Pharmacokinetics of PA-824 in Smear-Positive Tuberculosis Patients

(2010) A. H. Diacon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Safety, Tolerability, and Pharmacokinetics of PA-824 in Healthy Subjects

(2009) A. M. Ginsberg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Treatment of Active Pulmonary Tuberculosis in Adults: Current Standards and Recent Advances

(2009) Ronald G Hall et al.   PHARMACOTHERAPY