Insect Cecropins, Antimicrobial Peptides with Potential Therapeutic Applications

Musca domestica Cecropin (Mdc) Alleviates Salmonella typhimurium-Induced Colonic Mucosal Barrier Impairment: Associating With Inflammatory and Oxidative Stress Response, Tight Junction as Well as Intestinal Flora

(2019) Lun Zhang et al.   Frontiers in Microbiology

Cationic antimicrobial peptides: alternatives and/or adjuvants to antibiotics active against methicillin-resistant Staphylococcus aureus and multidrug-resistant Pseudomonas aeruginosa

(2019) Regina Geitani et al.   BMC MICROBIOLOGY

Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gram-negative sepsis

(2019) Jieun Kim et al.   Scientific Reports

Enhanced Silkworm Cecropin B Antimicrobial Activity against Pseudomonas aeruginosa from Single Amino Acid Variation

(2019) Ottavia Romoli et al.   ACS Infectious Diseases

Cecropin-like antimicrobial peptide protects mice from lethal E.coli infection

(2019) Anishma Shrestha et al.   PLoS One

Antibiotic-Resistant Infection Treatment Costs Have Doubled Since 2002, Now Exceeding $2 Billion Annually

(2018) Kenneth E. Thorpe et al.   HEALTH AFFAIRS

Therapeutic effects of antimicrobial peptide on malignant ascites in a mouse model

(2018) Li‑Jie Xia et al.   Molecular Medicine Reports

Identification and screening of potent antimicrobial peptides in arthropod genomes

(2018) Deepesh Duwadi et al.   PEPTIDES

Intrinsic antimicrobial properties of silk spun by genetically modified silkworm strains

(2018) Alessio Saviane et al.   TRANSGENIC RESEARCH

Recent Progress in the Chemical Synthesis of Class II and S-Glycosylated Bacteriocins

(2018) François Bédard et al.   Frontiers in Microbiology

Antimicrobial Peptides and Nanotechnology, Recent Advances and Challenges

(2018) Lubhandwa S. Biswaro et al.   Frontiers in Microbiology

Design and Assessment of Anti-Biofilm Peptides: Steps Toward Clinical Application

(2018) Melanie Dostert et al.   Journal of Innate Immunity

Anti-inflammatory activities of Aedes aegypti cecropins and their protection against murine endotoxin shock

(2018) Lin Wei et al.   Parasites & Vectors

A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties

(2018) Jiarong Wang et al.   PeerJ

Antimicrobial Peptides: the Achilles’ Heel of Antibiotic Resistance?

(2018) Angélique Lewies et al.   Probiotics and Antimicrobial Proteins

Insect Antimicrobial Peptides, a Mini Review

(2018) Qinghua Wu et al.   Toxins

Cecropin-Melittin Functionalized Polyurethane Surfaces Prevent Staphylococcus epidermidis Adhesion without Inducing Platelet Adhesion and Activation

(2018) Micaela M. Querido et al.   Advanced Materials Interfaces

A potential food biopreservative, CecXJ-37N, non-covalently intercalates into the nucleotides of bacterial genomic DNA beyond membrane attack

(2017) Dongliang Liu et al.   FOOD CHEMISTRY

Insect proteins as a potential source of antimicrobial peptides in livestock production. A review

(2017) A. Józefiak et al.   JOURNAL OF ANIMAL AND FEED SCIENCES

Rapid expansion of immune-related gene families in the house fly, Musca domestica

(2017) Timothy B. Sackton et al.   MOLECULAR BIOLOGY AND EVOLUTION

Inflammatory responses and inflammation-associated diseases in organs

(2017) Linlin Chen et al.   Oncotarget

Differential sensitivity to infections and antimicrobial peptide-mediated immune response in four silkworm strains with different geographical origin

(2017) Ottavia Romoli et al.   Scientific Reports

A novel cecropin-like peptide from black soldier fly, Hermetia illucens : Isolation, structural and functional characterization

(2017) Soon-Ik Park et al.   ENTOMOLOGICAL RESEARCH

Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species

(2017) Sarah G. Whaley et al.   Frontiers in Microbiology

Combination Strategies to Enhance the Efficacy of Antimicrobial Peptides against Bacterial Biofilms

(2017) Lucia Grassi et al.   Frontiers in Microbiology

Antimicrobial Peptides in Biomedical Device Manufacturing

(2017) Martijn Riool et al.   Frontiers in Chemistry

Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle

(2017) Lily Johanna Toro Segovia et al.   PLoS One

Characterization and functional study of a Cecropin-like peptide from the Chinese oak silkworm,Antheraea pernyi

(2016) Shao-Liang Fang et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

One-step synthesis of high-density peptide-conjugated gold nanoparticles with antimicrobial efficacy in a systemic infection model

(2016) Akhilesh Rai et al.   BIOMATERIALS

Antimicrobial peptides

(2016) Ling-juan Zhang et al.   CURRENT BIOLOGY

The Medical Potential of Antimicrobial Peptides from Insects

(2016) Miray Tonk et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Antimicrobial activity of mosquito cecropin peptides against Francisella

(2016) Akanksha Kaushal et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Bombyx mori cecropin A has a high antifungal activity to entomopathogenic fungus Beauveria bassiana

(2016) Dingding Lu et al.   GENE

Antimicrobial activity and interactions of cationic peptides derived from Galleria mellonella cecropin D-like peptide with model membranes

(2016) José Oñate-Garzón et al.   JOURNAL OF ANTIBIOTICS

Biofilms: an emergent form of bacterial life

(2016) Hans-Curt Flemming et al.   NATURE REVIEWS MICROBIOLOGY

The potential for adaptive maintenance of diversity in insect antimicrobial peptides

(2016) Robert L. Unckless et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Diversity, evolution and medical applications of insect antimicrobial peptides

(2016) Eleftherios Mylonakis et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Activity of antimicrobial peptides, alone or combined with conventional antibiotics, against Staphylococcus aureus isolated from the airways of cystic fibrosis patients

(2016) Katarzyna Garbacz et al.   Virulence

Bactericidal Hydrogels via Surface Functionalization with Cecropin A

(2016) Megan A. Cole et al.   ACS Biomaterials-Science & Engineering

Bactericidal Hydrogels via Surface Functionalization with Cecropin A

(2016) Megan A. Cole et al.   ACS Biomaterials Science & Engineering

Antimicrobial Peptide CMA3 Derived from the CA-MA Hybrid Peptide: Antibacterial and Anti-inflammatory Activities with Low Cytotoxicity and Mechanism of Action in Escherichia coli

(2015) Jong-kook Lee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Insect-Derived Cecropins Display Activity against Acinetobacter baumannii in a Whole-Animal High-Throughput Caenorhabditis elegans Model

(2015) Elamparithi Jayamani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial Peptides Expressed in Medicinal Maggots of the Blow Fly Lucilia sericata Show Combinatorial Activity against Bacteria

(2015) Anne-Kathrin Pöppel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Sequence diversity and evolution of antimicrobial peptides in invertebrates

(2015) Anchalee Tassanakajon et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Inhibition of porcine reproductive and respiratory syndrome virus by Cecropin D in vitro

(2015) Xiaohong Liu et al.   INFECTION GENETICS AND EVOLUTION

On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and LPS-induced cell death

(2015) Douglas B. Kell et al.   Integrative Biology

CecropinXJ inhibits the proliferation of human gastric cancer BGC823 cells and induces cell death in vitro and in vivo

(2015) YAN-LING WU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

APD3: the antimicrobial peptide database as a tool for research and education

(2015) Guangshun Wang et al.   NUCLEIC ACIDS RESEARCH

A cecropin-like antimicrobial peptide with anti-inflammatory activity from the black fly salivary glands

(2015) Jing Wu et al.   Parasites & Vectors

A potent anti-inflammatory peptide from the salivary glands of horsefly

(2015) Lin Wei et al.   Parasites & Vectors

Agriculture and food animals as a source of antimicrobial-resistant bacteria

(2015) Vangelis Economou et al.   Infection and Drug Resistance

Functional Roles of Aromatic Residues and Helices of Papiliocin in its Antimicrobial and Anti-inflammatory Activities

(2015) Eunjung Lee et al.   Scientific Reports

Insect antimicrobial peptides and their applications

(2014) Hui-Yu Yi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

ANTI-INFLAMMATORY ACTIVITIES OF CECROPIN A AND ITS MECHANISM OF ACTION

(2014) Eunjung Lee et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Cecropin A–melittin mutant with improved proteolytic stability and enhanced antimicrobial activity against bacteria and fungi associated with gastroenteritis in vitro

(2014) Shengyue Ji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Production of cecropin A antimicrobial peptide in rice seed endosperm

(2014) Mireia Bundó et al.   BMC PLANT BIOLOGY

Channel-Forming Activity of Cecropins in Lipid Bilayers: Effect of Agents Modifying the Membrane Dipole Potential

(2014) Svetlana S. Efimova et al.   LANGMUIR

Inhibition and destruction of Pseudomonas aeruginosa biofilms by antibiotics and antimicrobial peptides

(2014) Sibel Dosler et al.   PEPTIDES

Phylogenomics resolves the timing and pattern of insect evolution

(2014) B. Misof et al.   SCIENCE

Transmission Electron Microscopic Morphological Study and Flow Cytometric Viability Assessment ofAcinetobacter baumanniiSusceptible toMusca domesticacecropin

(2014) Shuiqing Gui et al.   TheScientificWorldJOURNAL

Antimicrobials, Stress and Mutagenesis

(2014) Alexandro Rodríguez-Rojas et al.   PLoS Pathogens

Expression, cDNA cloning, and characterization of the antibacterial peptide cecropin D fromAgrius convolvuli

(2013) Soon-Ik Park et al.   Animal Cells and Systems

Production of Homozygous Transgenic Rainbow Trout with Enhanced Disease Resistance

(2013) Pinwen Peter Chiou et al.   MARINE BIOTECHNOLOGY

The Cytotoxic Effect of Magainin II on the MDA-MB-231 and M14K Tumour Cell Lines

(2013) Radu Anghel et al.   Biomed Research International

In VitroActivities of Antibiotics and Antimicrobial Cationic Peptides Alone and in Combination against Methicillin-Resistant Staphylococcus aureus Biofilms

(2012) Emel Mataraci et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Novel Antimicrobial Peptide Derived from the Insect Paederus dermatitis

(2012) Mina Memarpoor-Yazdi et al.   International Journal of Peptide Research and Therapeutics

Anti-Listeria Activities of Galleria mellonella Hemolymph Proteins

(2011) Krishnendu Mukherjee et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bactericidal activity of Musca domestica cecropin (Mdc) on multidrug-resistant clinical isolate of Escherichia coli

(2011) X. Lu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Distribution and characteristics of ABFs, cecropins, nemapores, and lysozymes in nematodes

(2011) D. Ellen K. Tarr   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Structure and Function of Papiliocin with Antimicrobial and Anti-inflammatory Activities Isolated from the Swallowtail Butterfly,Papilio xuthus

(2011) Jin-Kyoung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antimicrobial and Anti-Inflammatory Effects of Cecropin A(1-8)–Magainin2(1-12) Hybrid Peptide Analog P5 against Malassezia furfur Infection in Human Keratinocytes

(2011) Sunhyo Ryu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Functional Divergence among Silkworm Antimicrobial Peptide Paralogs by the Activities of Recombinant Proteins and the Induced Expression Profiles

(2011) Wanying Yang et al.   PLoS One

Apoptosis-inducing activity of the antimicrobial peptide cecropin of Musca domestica in human hepatocellular carcinoma cell line BEL-7402 and the possible mechanism

(2010) X. Jin et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Expression of the antimicrobial peptide cecropin fused with human lysozyme in Escherichia coli

(2010) Xue-mei Lu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Antibacterial Activity and Synergism of the Hybrid Antimicrobial Peptide, CAMA-syn

(2010)   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Characterization and cDNA cloning of a cecropin-like antimicrobial peptide, papiliocin, from the swallowtail butterfly, Papilio xuthus

(2010) Seong Ryul Kim et al.   MOLECULES AND CELLS

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells

(2008) Henrik Suttmann et al.   BMC Urology

Surface modification and properties of Bombyx mori silk fibroin films by antimicrobial peptide

(2007) Liqiang Bai et al.   APPLIED SURFACE SCIENCE