Inducible Cardiac-Specific Deletion of Sirt1 in Male Mice Reveals Progressive Cardiac Dysfunction and Sensitization of the Heart to Pressure Overload
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inducible Cardiac-Specific Deletion of Sirt1 in Male Mice Reveals Progressive Cardiac Dysfunction and Sensitization of the Heart to Pressure Overload
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 20, Pages 5005
Publisher
MDPI AG
Online
2019-10-11
DOI
10.3390/ijms20205005
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sirt1 promotes autophagy and inhibits apoptosis to protect cardiomyocytes from hypoxic stress
- (2019) Guiping Luo et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Mitochondrial Morphology, Dynamics, and Function in Human Pressure Overload or Ischemic Heart Disease With Preserved or Reduced Ejection Fraction
- (2019) Antoine H. Chaanine et al. Circulation-Heart Failure
- Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca 2+ -ATPase in Heart Failure
- (2019) Przemyslaw A Gorski et al. CIRCULATION RESEARCH
- SIRT1 and SIRT6 Signaling Pathways in Cardiovascular Disease Protection
- (2018) Nunzia D'Onofrio et al. ANTIOXIDANTS & REDOX SIGNALING
- Sirtuin 1 activation attenuates cardiac fibrosis in a rodent pressure overload model by modifying Smad2/3 transactivation
- (2018) Antoinette Bugyei-Twum et al. CARDIOVASCULAR RESEARCH
- Cardiomyocyte-specific deletion of Sirt1 gene sensitizes myocardium to ischaemia and reperfusion injury
- (2018) Lin Wang et al. CARDIOVASCULAR RESEARCH
- SIRT1 increases cardiomyocyte binucleation in the heart development
- (2018) Alexandra N Shin et al. Oncotarget
- PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis
- (2018) Maayan Waldman et al. EXPERIMENTAL CELL RESEARCH
- Sirtuin 1 protects the aging heart from contractile dysfunction mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific Sirtuin 1 knockout mouse model
- (2017) Yu-Juei Hsu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Cobalamin and folate protect mitochondrial and contractile functions in a murine model of cardiac pressure overload
- (2017) Jérôme Piquereau et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation
- (2016) Alexandre Prola et al. CELL DEATH AND DIFFERENTIATION
- The role of sirtuins in cardiac disease
- (2015) Shouji Matsushima et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Reduced SIRT1 expression correlates with enhanced oxidative stress in compensated and decompensated heart failure
- (2015) Feridun Akkafa et al. Redox Biology
- Sirtuin 1 ablation in endothelial cells is associated with impaired angiogenesis and diastolic dysfunction
- (2014) Julien Maizel et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Protective role of PARK2/Parkin in sepsis-induced cardiac contractile and mitochondrial dysfunction
- (2013) Jérôme Piquereau et al. Autophagy
- Cardiac fibrosis in mice expressing an inducible myocardial-specific Cre driver
- (2013) J. Lexow et al. Disease Models & Mechanisms
- Moderate and high amounts of tamoxifen in MHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death
- (2013) K. Bersell et al. Disease Models & Mechanisms
- SIRT1 and energy metabolism
- (2012) X. Li ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Cardiac Aging: From Molecular Mechanisms to Significance in Human Health and Disease
- (2012) Dao-Fu Dai et al. ANTIOXIDANTS & REDOX SIGNALING
- Emerging beneficial roles of sirtuins in heart failure
- (2012) Masaya Tanno et al. BASIC RESEARCH IN CARDIOLOGY
- PARP-2 knockdown protects cardiomyocytes from hypertrophy via activation of SIRT1
- (2012) Biao Geng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Suppression of ERR targets by a PPARα/Sirt1 complex in the failing heart
- (2012) Shin-ichi Oka et al. CELL CYCLE
- Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart
- (2012) A. Planavila et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Protection of the Heart Against Ischemia/Reperfusion by Silent Information Regulator 1
- (2012) Takanobu Yamamoto et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Systolic dysfunction in cardiac-specific ligand-inducible MerCreMer transgenic mice
- (2011) Michael E. Hall et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- PPARα-Sirt1 Complex Mediates Cardiac Hypertrophy and Failure through Suppression of the ERR Transcriptional Pathway
- (2011) Shinichi Oka et al. Cell Metabolism
- Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice
- (2011) Tsuneaki Kawashima et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy
- (2011) N. R. Sundaresan et al. Science Signaling
- PGC-1 coactivators in the cardiovascular system
- (2011) Ian S. Patten et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion
- (2010) Chiao-Po Hsu et al. CIRCULATION
- Postnatal development of mouse heart: formation of energetic microdomains
- (2010) Jérôme Piquereau et al. JOURNAL OF PHYSIOLOGY-LONDON
- Transcriptional control of mitochondrial biogenesis: the central role of PGC-1
- (2008) R. Ventura-Clapier et al. CARDIOVASCULAR RESEARCH
- PGC-1α and ERRα target gene downregulation is a signature of the failing human heart
- (2008) Smita Sihag et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells
- (2008) Andrey V Kuznetsov et al. Nature Protocols
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started