Refining the therapeutic range of posaconazole and isavuconazole for efficient therapeutic drug monitoring using a bioassay approach

Antifungal Prophylaxis with Posaconazole Delayed-Release Tablet and Oral Suspension in a Real-Life Setting: Plasma Levels, Efficacy, and Tolerability

(2018) David Lenczuk et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isavuconazole Concentration in Real-World Practice: Consistency with Results from Clinical Trials

(2018) David Andes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Posaconazole Tablets in Real-Life Lung Transplantation: Impact on Exposure, Drug-Drug Interactions, and Drug Management in Lung Transplant Patients, Including Those with Cystic Fibrosis

(2018) Manon Launay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isavuconazole is highly active in vitro against Candida species isolates but shows trailing effect

(2018) Laura Judith Marcos-Zambrano et al.   CLINICAL MICROBIOLOGY AND INFECTION

Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline

(2018) A.J. Ullmann et al.   CLINICAL MICROBIOLOGY AND INFECTION

Low dose posaconazole delayed release tablets for fungal prophylaxis in lung transplant recipients

(2018) Jade M. Kozuch et al.   CLINICAL TRANSPLANTATION

Direct in vitro comparison of the prodrug isavuconazonium sulfate with the isavuconazole active compound against Aspergillus spp. and 2 rare moulds

(2018) Michael A. Pfaller et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Alternative approaches to the therapeutic drug monitoring of prophylactic posaconazole in haematology patients

(2018) T.-A. Vyzantiadis et al.   JOURNAL DE MYCOLOGIE MEDICALE

In Vitro Activity of Isavuconazole against Opportunistic Fungal Pathogens from Two Mycology Reference Laboratories

(2018) Michael A. Pfaller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of Intravenous Isavuconazole in Solid-Organ Transplant Recipients

(2018) Xuemei Wu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isavuconazole Kinetic Exploration for Clinical Practice

(2018) Léa Darnaud et al.   Drugs in research & development

Persistent CNS toxicity in a patient receiving posaconazole tablets after discontinuation of voriconazole due to supratherapeutic serum levels

(2017) Farnaz Foolad et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Single-centre study of therapeutic drug monitoring of posaconazole in lung transplant recipients: factors affecting trough plasma concentrations

(2017) Wirawan Jeong et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease

(2017) Oliver A Cornely et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Multicentre study of posaconazole delayed-release tablet serum level and association with hepatotoxicity and QTc prolongation

(2017) Natasha N. Pettit et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Isavuconazole susceptibility of clinical Aspergillus fumigatus isolates and feasibility of isavuconazole dose escalation to treat isolates with elevated MICs

(2017) Jochem B Buil et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Safety study and therapeutic drug monitoring of the oral tablet formulation of posaconazole in patients with haematological malignancies

(2017) C. Boglione-Kerrien et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Posaconazole liquid vs tablet formulation in lung transplant recipients

(2017) D. Stelzer et al.   MYCOSES

Pharmacokinetics and Concentration-Dependent Efficacy of Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis

(2016) Vidmantas Petraitis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial

(2016) Johan A Maertens et al.   LANCET

Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis

(2016) Francisco M Marty et al.   LANCET INFECTIOUS DISEASES

Retrospective Comparison of Posaconazole Levels in Patients Taking the Delayed-Release Tablet versus the Oral Suspension

(2015) Urshila Durani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bioassay for Determining Voriconazole Serum Levels in Patients Receiving Combination Therapy with Echinocandins

(2015) Maria Siopi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Superior Serum Concentrations with Posaconazole Delayed-Release Tablets Compared to Suspension Formulation in Hematological Malignancies

(2015) Aaron Cumpston et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phase 3 pharmacokinetics and safety study of a posaconazole tablet formulation in patients at risk for invasive fungal disease

(2015) Oliver A. Cornely et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Drug-drug interaction between isavuconazole and tacrolimus: a case report indicating the need for tacrolimus drug-level monitoring

(2015) T. Kim et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Serum posaconazole levels among haematological cancer patients taking extended release tablets is affected by body weight and diarrhoea: single centre retrospective analysis

(2015) Marisa H. Miceli et al.   MYCOSES

Contribution of a Simple Bioassay in Effective Therapeutic Drug Monitoring of Posaconazole and Voriconazole

(2015) Julia Tonini et al.   THERAPEUTIC DRUG MONITORING

Switching from Posaconazole Suspension to Tablets Increases Serum Drug Levels in Leukemia Patients without Clinically Relevant Hepatotoxicity

(2014) Dong Sik Jung et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Simultaneous quantitation of azole antifungals, antibiotics, imatinib, and raltegravir in human plasma by two-dimensional high-performance liquid chromatography–tandem mass spectrometry

(2013) Jean-François Jourdil et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

HPLC/UV or bioassay: two valid methods for posaconazole quantification in human serum samples

(2011) E. Cendejas-Bueno et al.   CLINICAL MICROBIOLOGY AND INFECTION

Microsatellite typing of Aspergillus fumigatus isolates recovered from deep organ samples of patients with invasive aspergillosis

(2008) Lies M.E. Vanhee et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE