Clinical implications of recent advances in primary open-angle glaucoma genetics
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Clinical implications of recent advances in primary open-angle glaucoma genetics
Authors
Keywords
-
Journal
EYE
Volume 34, Issue 1, Pages 29-39
Publisher
Springer Science and Business Media LLC
Online
2019-10-23
DOI
10.1038/s41433-019-0632-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density
- (2019) Erna V. Ivarsdottir et al. Nature Communications
- Benefits and limitations of genome-wide association studies
- (2019) Vivian Tam et al. NATURE REVIEWS GENETICS
- Association of Statin Use and High Serum Cholesterol Levels With Risk of Primary Open-Angle Glaucoma
- (2019) Jae H. Kang et al. JAMA Ophthalmology
- Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis
- (2019) Bao Jian Fan et al. JAMA Ophthalmology
- Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma
- (2018) Yukihiro Shiga et al. HUMAN MOLECULAR GENETICS
- A Common Glaucoma-risk Variant of SIX6 Alters Retinal Nerve Fiber Layer and Optic Disc Measures in a European Population
- (2018) Anthony P. Khawaja et al. JOURNAL OF GLAUCOMA
- Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma
- (2018) Anthony P. Khawaja et al. NATURE GENETICS
- Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma
- (2018) Stuart MacGregor et al. NATURE GENETICS
- Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
- (2018) Adriana I. Iglesias et al. Nature Communications
- A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci
- (2018) Hélène Choquet et al. Nature Communications
- Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma
- (2018) Puya Gharahkhani et al. Scientific Reports
- Protecting Pax6 3’UTR from microRNA-7 partially restores PAX6 in islets from an aniridia mouse model.
- (2018) Kevin Yongblah et al. Molecular Therapy-Nucleic Acids
- Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations
- (2018) Pieter W. M. Bonnemaijer et al. HUMAN GENETICS
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent
- (2018) Kent D. Taylor et al. OPHTHALMOLOGY
- Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma
- (2017) Jeffrey O’Callaghan et al. HUMAN MOLECULAR GENETICS
- Genetics of glaucoma
- (2017) Janey L. Wiggs et al. HUMAN MOLECULAR GENETICS
- Angiopoietin-1 is required for Schlemm’s canal development in mice and humans
- (2017) Benjamin R. Thomson et al. JOURNAL OF CLINICAL INVESTIGATION
- Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci
- (2017) Tin Aung et al. NATURE GENETICS
- Genetic architecture: the shape of the genetic contribution to human traits and disease
- (2017) Nicholas J. Timpson et al. NATURE REVIEWS GENETICS
- Myocilin Predictive Genetic Testing for Primary Open-Angle Glaucoma Leads to Early Identification of At-Risk Individuals
- (2017) Emmanuelle Souzeau et al. OPHTHALMOLOGY
- Whole exome sequencing implicates eye development, the unfolded protein response and plasma membrane homeostasis in primary open-angle glaucoma
- (2017) Tiger Zhou et al. PLoS One
- CRISPR-Cas9–based treatment of myocilin-associated glaucoma
- (2017) Ankur Jain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure
- (2017) Hélène Choquet et al. Nature Communications
- Pseudoexfoliation syndrome-associated genetic variants affect transcription factor binding and alternative splicing of LOXL1
- (2017) Francesca Pasutto et al. Nature Communications
- Phenome-wide heritability analysis of the UK Biobank
- (2017) Tian Ge et al. PLoS Genetics
- Mice Homozygous for a Deletion in the Glaucoma Susceptibility Locus INK4 Show Increased Vulnerability of Retinal Ganglion Cells to Elevated Intraocular Pressure
- (2016) Shan Gao et al. AMERICAN JOURNAL OF PATHOLOGY
- Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity
- (2016) Tomokazu Souma et al. JOURNAL OF CLINICAL INVESTIGATION
- Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma
- (2016) Jessica N Cooke Bailey et al. NATURE GENETICS
- Detection and interpretation of shared genetic influences on 42 human traits
- (2016) Joseph K Pickrell et al. NATURE GENETICS
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Integrative approaches for large-scale transcriptome-wide association studies
- (2016) Alexander Gusev et al. NATURE GENETICS
- The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
- (2016) Jacqueline MacArthur et al. NUCLEIC ACIDS RESEARCH
- Assessment of polygenic effects links primary open-angle glaucoma and age-related macular degeneration
- (2016) Gabriel Cuellar-Partida et al. Scientific Reports
- The African Descent and Glaucoma Evaluation Study (ADAGES): Predictors of Visual Field Damage in Glaucoma Suspects
- (2015) Naira Khachatryan et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Neurodegeneration severity can be predicted from early microglia alterations monitored in vivo in a mouse model of chronic glaucoma
- (2015) A. Bosco et al. Disease Models & Mechanisms
- Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
- (2015) Mark N. Kvale et al. GENETICS
- Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
- (2015) Yambazi Banda et al. GENETICS
- A common variant near TGFBR3 is associated with primary open angle glaucoma
- (2015) Zheng Li et al. HUMAN MOLECULAR GENETICS
- ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure
- (2015) H. Springelkamp et al. HUMAN MOLECULAR GENETICS
- Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial
- (2015) David F Garway-Heath et al. LANCET
- P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma
- (2015) Dorota Skowronska-Krawczyk et al. MOLECULAR CELL
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
- (2015) Lars G Fritsche et al. NATURE GENETICS
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- A gene-based association method for mapping traits using reference transcriptome data
- (2015) Eric R Gamazon et al. NATURE GENETICS
- Genetics of Primary Inherited Disorders of the Optic Nerve: Clinical Applications
- (2015) Keri F. Allen et al. Cold Spring Harbor Perspectives in Medicine
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
- (2015) Mark N. Kvale et al. GENETICS
- Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
- (2015) Yambazi Banda et al. GENETICS
- Newer targets for modulation of intraocular pressure: focus on adenosine receptor signaling pathways
- (2014) Renu Agarwal et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative
- (2014) Thomas J. Hoffmann et al. HUMAN MOLECULAR GENETICS
- A lymphatic defect causes ocular hypertension and glaucoma in mice
- (2014) Benjamin R. Thomson et al. JOURNAL OF CLINICAL INVESTIGATION
- The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel
- (2014) Aleksanteri Aspelund et al. JOURNAL OF CLINICAL INVESTIGATION
- Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma
- (2014) Puya Gharahkhani et al. NATURE GENETICS
- Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma
- (2014) Pirro G Hysi et al. NATURE GENETICS
- Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma
- (2014) Yuhong Chen et al. NATURE GENETICS
- VEGAS2: Software for More Flexible Gene-Based Testing
- (2014) Aniket Mishra et al. Twin Research and Human Genetics
- Schlemm's Canal Is a Unique Vessel with a Combination of Blood Vascular and Lymphatic Phenotypes that Forms by a Novel Developmental Process
- (2014) Krishnakumar Kizhatil et al. PLOS BIOLOGY
- Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma
- (2014) Megan Ulmer Carnes et al. PLoS Genetics
- Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation–differentiation balance early in life and optic nerve degeneration at old age
- (2013) Adriana I. Iglesias et al. HUMAN MOLECULAR GENETICS
- Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration
- (2013) Johanna M Seddon et al. NATURE GENETICS
- Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus
- (2013) Yi Lu et al. NATURE GENETICS
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia
- (2013) Virginie J M Verhoeven et al. NATURE GENETICS
- The EPIC-Norfolk Eye Study: rationale, methods and a cross-sectional analysis of visual impairment in a population-based cohort
- (2013) Anthony P Khawaja et al. BMJ Open
- Genetic Testing for Inherited Eye Disease
- (2013) Janey L. Wiggs et al. JAMA Ophthalmology
- A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma
- (2012) Wael Osman et al. HUMAN MOLECULAR GENETICS
- Baseline Risk Factors that Predict the Development of Open-Angle Glaucoma in a Population
- (2012) Xuejuan Jiang et al. OPHTHALMOLOGY
- Common Variants in CDKN2B-AS1 Associated with Optic-Nerve Vulnerability of Glaucoma Identified by Genome-Wide Association Studies in Japanese
- (2012) Masakazu Nakano et al. PLoS One
- CDKN2B Polymorphism Is Associated with Primary Open-Angle Glaucoma (POAG) in the Afro-Caribbean Population of Barbados, West Indies
- (2012) Dan Cao et al. PLoS One
- Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma
- (2012) Janey L. Wiggs et al. PLoS Genetics
- Abundant Pleiotropy in Human Complex Diseases and Traits
- (2011) Shanya Sivakumaran et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1
- (2011) Kathryn P Burdon et al. NATURE GENETICS
- Early microglia activation in a mouse model of chronic glaucoma
- (2010) Alejandra Bosco et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma
- (2010) Gudmar Thorleifsson et al. NATURE GENETICS
- The Heritability of Ocular Traits
- (2010) Paul G. Sanfilippo et al. SURVEY OF OPHTHALMOLOGY
- A Genome-Wide Association Study of Optic Disc Parameters
- (2010) Wishal D. Ramdas et al. PLoS Genetics
- Primary Open-Angle Glaucoma
- (2009) Young H. Kwon et al. NEW ENGLAND JOURNAL OF MEDICINE
- The sine oculis homeobox (SIX) family of transcription factors as regulators of development and disease
- (2008) J. P. Kumar CELLULAR AND MOLECULAR LIFE SCIENCES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now