Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation–differentiation balance early in life and optic nerve degeneration at old age

Reprogramming amacrine and photoreceptor progenitors into retinal ganglion cells by replacing Neurod1 with Atoh7

(2013) C.-A. Mao et al.   DEVELOPMENT

Exon-level expression profiling of ocular tissues

(2013) Alex H. Wagner et al.   EXPERIMENTAL EYE RESEARCH

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

The Heritability of Glaucoma-Related Traits Corneal Hysteresis, Central Corneal Thickness, Intraocular Pressure, and Choroidal Blood Flow Pulsatility

(2013) Ellen E. Freeman et al.   PLoS One

Genetic Investigation into the Endophenotypic Status of Central Corneal Thickness and Optic Disc Parameters in Relation to Open-Angle Glaucoma

(2012) David P. Dimasi et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

CDKN2B-AS1 Genotype–Glaucoma Feature Correlations in Primary Open-Angle Glaucoma Patients From the United States

(2012) Louis R. Pasquale et al.   AMERICAN JOURNAL OF OPHTHALMOLOGY

A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma

(2012) Wael Osman et al.   HUMAN MOLECULAR GENETICS

Math5 (Atoh7) gene dosage limits retinal ganglion cell genesis

(2012) Lev Prasov et al.   NEUROREPORT

Glaucoma Risk Alleles at CDKN2B-AS1 Are Associated with Lower Intraocular Pressure, Normal-Tension Glaucoma, and Advanced Glaucoma

(2012) Kathryn P. Burdon et al.   OPHTHALMOLOGY

Common Variants in CDKN2B-AS1 Associated with Optic-Nerve Vulnerability of Glaucoma Identified by Genome-Wide Association Studies in Japanese

(2012) Masakazu Nakano et al.   PLoS One

CDKN2B Polymorphism Is Associated with Primary Open-Angle Glaucoma (POAG) in the Afro-Caribbean Population of Barbados, West Indies

(2012) Dan Cao et al.   PLoS One

Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma

(2012) Janey L. Wiggs et al.   PLoS Genetics

Lifestyle and Risk of Developing Open-Angle Glaucoma

(2011) Wishal D. Ramdas   ARCHIVES OF OPHTHALMOLOGY

NARWHAL, a primary analysis pipeline for NGS data

(2011) R. W. W. Brouwer et al.   BIOINFORMATICS

The Rotterdam Study: 2012 objectives and design update

(2011) Albert Hofman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA

(2011) Janey L. Wiggs et al.   HUMAN MOLECULAR GENETICS

Common genetic variants associated with open-angle glaucoma

(2011) Wishal D. Ramdas et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1

(2011) Kathryn P Burdon et al.   NATURE GENETICS

Mutations in Zebrafish lrp2 Result in Adult-Onset Ocular Pathogenesis That Models Myopia and Other Risk Factors for Glaucoma

(2011) Kerry N. Veth et al.   PLoS Genetics

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Genetic architecture of open angle glaucoma and related determinants

(2010) W. D. Ramdas et al.   JOURNAL OF MEDICAL GENETICS

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

(2010) Gudmar Thorleifsson et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Single-nucleotide evolutionary constraint scores highlight disease-causing mutations

(2010) Gregory M Cooper et al.   NATURE METHODS

Incidence of Glaucomatous Visual Field Loss: A Ten-Year Follow-up from the Rotterdam Study

(2010) Monika A. Czudowska et al.   OPHTHALMOLOGY

Characterization of drCol 15a1b: A Novel Component of the Stem Cell Niche in the Zebrafish Retina

(2010) Veronica Gonzalez-Nunez et al.   STEM CELLS

A Genome-Wide Association Study of Optic Disc Parameters

(2010) Wishal D. Ramdas et al.   PLoS Genetics

From Progenitors to Differentiated Cells in the Vertebrate Retina

(2009) Michalis Agathocleous et al.   Annual Review of Cell and Developmental Biology

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Primary Open-Angle Glaucoma

(2009) Young H. Kwon et al.   NEW ENGLAND JOURNAL OF MEDICINE

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

(2008) A. J. Vilella et al.   GENOME RESEARCH