Elucidation of WW domain ligand binding specificities in the Hippo pathway reveals STXBP 4 as YAP inhibitor

Tensile Forces and Mechanotransduction at Cell–Cell Junctions

(2018) Guillaume Charras et al.   CURRENT BIOLOGY

α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart

(2018) Alexia Vite et al.   DEVELOPMENT

STXBP4 regulates APC/C-mediated p63 turnover and drives squamous cell carcinogenesis

(2018) Susumu Rokudai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction

(2018) Apoorva Verma et al.   Oncotarget

The Immunoexpression of YAP1 and LATS1 Proteins in Clear Cell Renal Cell Carcinoma: Impact on Patients’ Survival

(2018) J. Godlewski et al.   Biomed Research International

The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ

(2018) Lei Chang et al.   NATURE

Computational Analysis of Breast Cancer GWAS Loci Identifies the Putative Deleterious Effect of STXBP4 and ZNF404 Gene Variants

(2017) Tariq Ahmad Masoodi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Architecture of the human interactome defines protein communities and disease networks

(2017) Edward L. Huttlin et al.   NATURE

YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis

(2017) Yiting Qiao et al.   Cell Reports

Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration

(2016) Xu Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calculating protein-ligand binding affinities with MMPBSA: Method and error analysis

(2016) Changhao Wang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family

(2016) Xu Li et al.   MOLECULAR & CELLULAR PROTEOMICS

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma

(2016) Omid Tavana et al.   NATURE MEDICINE

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)

(2016) Hatef Darabi et al.   Scientific Reports

MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories

(2015) Robert T. McGibbon et al.   BIOPHYSICAL JOURNAL

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors

(2015) Jennifer L. Caswell et al.   HUMAN MOLECULAR GENETICS

Applications of MMPBSA to Membrane Proteins I: Efficient Numerical Solutions of Periodic Poisson–Boltzmann Equation

(2015) Wesley M. Botello-Smith et al.   Journal of Chemical Information and Modeling

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

RUNX3 is a novel negative regulator of oncogenic TEAD–YAP complex in gastric cancer

(2015) Y Qiao et al.   ONCOGENE

Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis

(2015) Chao Wang et al.   Nature Communications

Cytoskeletal Tension Inhibits Hippo Signaling through an Ajuba-Warts Complex

(2014) Cordelia Rauskolb et al.   CELL

YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

(2014) Boon Chuan Low et al.   FEBS LETTERS

PTPN14 Forms a Complex with Kibra and LATS1 Proteins and Negatively Regulates the YAP Oncogenic Function

(2014) Kayla E. Wilson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterizing WW Domain Interactions of Tumor Suppressor WWOX Reveals Its Association with Multiprotein Networks

(2014) Mohammad Abu-Odeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis

(2014) JIAN-JIA CAO et al.   ONCOLOGY REPORTS

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration

(2014) J. W. Haskins et al.   Science Signaling

Hippo Signaling Mediates Proliferation, Invasiveness, and Metastatic Potential of Clear Cell Renal Cell Carcinoma

(2014) Ute Schütte et al.   Translational Oncology

NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation

(2013) Zaidoun Salah et al.   CELL CYCLE

Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy

(2013) Anna Ulbricht et al.   CURRENT BIOLOGY

Synip Arrests SolubleN-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (SNARE)-dependent Membrane Fusion as a Selective Target Membrane SNARE-binding Inhibitor

(2013) Haijia Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald

(2013) Romelia Salomon-Ferrer et al.   Journal of Chemical Theory and Computation

Defining the Protein–Protein Interaction Network of the Human Hippo Pathway

(2013) Wenqi Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1

(2013) Simon Hauri et al.   Molecular Systems Biology

The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity

(2013) Chrysiis Michaloglou et al.   PLoS One

WWP1 E3 Ligase Targets LATS1 for Ubiquitin-Mediated Degradation in Breast Cancer Cells

(2013) Benjamin Yeung et al.   PLoS One

Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions

(2013) A. L. Couzens et al.   Science Signaling

PTPN14 is required for the density-dependent control of YAP1

(2012) W. Wang et al.   GENES & DEVELOPMENT

Reducing Grid Dependence in Finite-Difference Poisson–Boltzmann Calculations

(2012) Jun Wang et al.   Journal of Chemical Theory and Computation

MMPBSA.py: An Efficient Program for End-State Free Energy Calculations

(2012) Bill R. Miller et al.   Journal of Chemical Theory and Computation

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

(2012) Andreas W. Götz et al.   Journal of Chemical Theory and Computation

The Proteomics Identifications (PRIDE) database and associated tools: status in 2013

(2012) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

PTPN14 interacts with and negatively regulates the oncogenic function of YAP

(2012) X Liu et al.   ONCOGENE

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways

(2012) Eric Aragón et al.   STRUCTURE

Premetazoan Origin of the Hippo Signaling Pathway

(2012) Arnau Sebé-Pedrós et al.   Cell Reports

Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity

(2011) Z. Salah et al.   CANCER RESEARCH

Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation

(2011) Karin Schlegelmilch et al.   CELL

Wbp2 cooperates with Yorkie to drive tissue growth downstream of the Salvador–Warts–Hippo pathway

(2011) X Zhang et al.   CELL DEATH AND DIFFERENTIATION

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

(2011) B. Zhao et al.   GENES & DEVELOPMENT

Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin

(2011) Siew Wee Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WW domain interactions regulate the Hippo tumor suppressor pathway

(2011) Z Salah et al.   Cell Death & Disease

Hippo signaling: growth control and beyond

(2010) G. Halder et al.   DEVELOPMENT

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded

(2010) Jianzhong Yu et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

Y65C Missense Mutation in the WW Domain of the Golabi-Ito-Hall Syndrome Protein PQBP1 Affects Its Binding Activity and Deregulates Pre-mRNA Splicing

(2010) Victor E. Tapia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiomotin-like Proteins Associate with and Negatively Regulate YAP1

(2010) Wenqi Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Modularity in the Hippo signaling pathway

(2010) Marius Sudol et al.   TRENDS IN BIOCHEMICAL SCIENCES

Performance of Nonlinear Finite-Difference Poisson−Boltzmann Solvers

(2009) Qin Cai et al.   Journal of Chemical Theory and Computation

Centrosome separation driven by actin-microfilaments during mitosis is mediated by centrosome-associated tyrosine-phosphorylated cortactin

(2008) W. Wang et al.   JOURNAL OF CELL SCIENCE