Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam

Ciliary Beating Compartmentalizes Cerebrospinal Fluid Flow in the Brain and Regulates Ventricular Development

(2019) Emilie W. Olstad et al.   CURRENT BIOLOGY

PDGF-B Is Required for Development of the Glymphatic System

(2019) Anne Sofie Munk et al.   Cell Reports

Characterization of a novel rat model of X-linked hydrocephalus by CRISPR-mediated mutation in L1cam

(2019) A. Scott Emmert et al.   JOURNAL OF NEUROSURGERY

Posthemorrhagic hydrocephalus development after germinal matrix hemorrhage: Established mechanisms and proposed pathways

(2019) Damon Klebe et al.   JOURNAL OF NEUROSCIENCE RESEARCH

When the air hits your brain: decreased arterial pulsatility after craniectomy leading to impaired glymphatic flow

(2019) Benjamin A. Plog et al.   JOURNAL OF NEUROSURGERY

Nonsense mutation in CFAP43 causes normal-pressure hydrocephalus with ciliary abnormalities

(2019) Yoshiro Morimoto et al.   NEUROLOGY

Visualizing flow in an intact CSF network using optical coherence tomography: implications for human congenital hydrocephalus

(2019) Priya Date et al.   Scientific Reports

A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice

(2018) Zakia Abdelhamed et al.   DEVELOPMENT

Role of MCP-1 and CCR2 in ethanol-induced neuroinflammation and neurodegeneration in the developing brain

(2018) Kai Zhang et al.   Journal of Neuroinflammation

Dynamics of Evans blue clearance from cerebrospinal fluid into meningeal lymphatic vessels and deep cervical lymph nodes

(2018) Marcela Maloveska et al.   NEUROLOGICAL RESEARCH

De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus

(2018) Charuta Gavankar Furey et al.   NEURON

Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus

(2018) Khadar Abdi et al.   Nature Communications

Human Genetics and Molecular Mechanisms of Congenital Hydrocephalus

(2018) Charuta Gavankar Furey et al.   World Neurosurgery

Quantitative and qualitative assessment of glymphatic flux using Evans blue albumin

(2018) Michael S. Wolf et al.   JOURNAL OF NEUROSCIENCE METHODS

The glymphatic pathway in neurological disorders

(2018) Martin Kaag Rasmussen et al.   LANCET NEUROLOGY

Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus

(2017) Jason K Karimy et al.   NATURE MEDICINE

Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice

(2017) Qiaoli Ma et al.   Nature Communications

Ventricular-subcutaneous shunt for the treatment of experimental hydrocephalus in young rats: technical note

(2016) Marcelo Volpon Santos et al.   CHILDS NERVOUS SYSTEM

Diffusion tensor imaging study of pediatric patients with congenital hydrocephalus: 1-year postsurgical outcomes

(2016) Francesco T. Mangano et al.   Journal of Neurosurgery-Pediatrics

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

The role of L1cam in murine corticogenesis, and the pathogenesis of hydrocephalus

(2015) Kyoko Itoh et al.   PATHOLOGY INTERNATIONAL

TLR2-induced astrocyte MMP9 activation compromises the blood brain barrier and exacerbates intracerebral hemorrhage in animal models

(2015) Hyunjung Min et al.   Molecular Brain

I'll take the low road: the evolutionary underpinnings of visually triggered fear

(2015) James A. Carr   Frontiers in Neuroscience

Infantile hydrocephalus: A review of epidemiology, classification and causes

(2014) Hannah M. Tully et al.   European Journal of Medical Genetics

Intracranial pressure measured in freely moving rats for days after intracerebral hemorrhage

(2014) Carmen Hiploylee et al.   EXPERIMENTAL NEUROLOGY

Extracellular hemoglobin - mediator of inflammation and cell death in the choroid plexus following preterm intraventricular hemorrhage

(2014) Magnus Gram et al.   Journal of Neuroinflammation

Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

(2014) Jeffrey J. Iliff et al.   JOURNAL OF NEUROSCIENCE

IL-1β Induces MMP-9-Dependent Brain Astrocytic Migration via Transactivation of PDGF Receptor/NADPH Oxidase 2-Derived Reactive Oxygen Species Signals

(2014) Chuen-Mao Yang et al.   MOLECULAR NEUROBIOLOGY

CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Impaired Glymphatic Perfusion After Strokes Revealed by Contrast-Enhanced MRI

(2014) Thomas Gaberel et al.   STROKE

Neuropathological review of 138 cases genetically tested for X-linked hydrocephalus: evidence for closely related clinical entities of unknown molecular bases

(2013) Homa Adle-Biassette et al.   ACTA NEUROPATHOLOGICA

Decorin prevents the development of juvenile communicating hydrocephalus

(2013) Hannah Botfield et al.   BRAIN

The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas

(2013) Helen Könnecke et al.   Clinical & Developmental Immunology

Gene targeting technologies in rats: Zinc finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeats

(2013) Tomoji Mashimo   DEVELOPMENT GROWTH & DIFFERENTIATION

Reduced subventricular zone proliferation and white matter damage in juvenile ferrets with kaolin-induced hydrocephalus

(2013) Domenico L. Di Curzio et al.   EXPERIMENTAL NEUROLOGY

Riding the wave of ependymal cilia: Genetic susceptibility to hydrocephalus in primary ciliary dyskinesia

(2013) Lance Lee   JOURNAL OF NEUROSCIENCE RESEARCH

Astrocytes acquire morphological and functional characteristics of ependymal cells following disruption of ependyma in hydrocephalus

(2012) Ruth Roales-Buján et al.   ACTA NEUROPATHOLOGICA

Models of Cranial Suture Biology

(2012) Monica Grova et al.   JOURNAL OF CRANIOFACIAL SURGERY

Mutation inMPDZcauses severe congenital hydrocephalus

(2012) Mohammed S Al-Dosari et al.   JOURNAL OF MEDICAL GENETICS

The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis

(2012) Shujun Ge et al.   Journal of Neuroinflammation

Nuclear Factor  B Activation Impairs Ependymal Ciliogenesis and Links Neuroinflammation to Hydrocephalus Formation

(2012) M. Lattke et al.   JOURNAL OF NEUROSCIENCE

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Focusing Forward Genetics: A Tripartite ENU Screen for Neurodevelopmental Mutations in the Mouse

(2011) R. W. Stottmann et al.   GENETICS

Development of hydrocephalus and classical hypothesis of cerebrospinal fluid hydrodynamics: Facts and illusions

(2011) D. Orešković et al.   PROGRESS IN NEUROBIOLOGY

Lysophosphatidic Acid Signaling May Initiate Fetal Hydrocephalus

(2011) Y. C. Yung et al.   Science Translational Medicine

Inflammation of the Choroid Plexus and Ependymal Layer of the Ventricle Following Intraventricular Hemorrhage

(2011) Philippe F. Simard et al.   Translational Stroke Research

Neuropathology and structural changes in hydrocephalus

(2010) Marc R. Del Bigio   Developmental Disabilities Research Reviews

The effect of intracranial pressure on myelination and the relationship with neurodevelopment in infantile hydrocephalus

(2010) P W. Hanlo et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Reactive astrocytosis, microgliosis and inflammation in rats with neonatal hydrocephalus

(2010) Kelley E. Deren et al.   EXPERIMENTAL NEUROLOGY

CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs

(2010) Anne-Christine Merveille et al.   NATURE GENETICS

Cytokine and Growth Factor Concentration in Cerebrospinal Fluid from Patients with Hydrocephalus Following Endovascular Embolization of Unruptured Aneurysms in Comparison with Other Types of Hydrocephalus

(2010) Monika Killer et al.   NEUROCHEMICAL RESEARCH