Unprogrammed epigenetic variation mediated by stochastic formation of ectopic heterochromatin

Regulation of ectopic heterochromatin-mediated epigenetic diversification by the JmjC family protein Epe1

(2019) Masato Sorida et al.   PLoS Genetics

Mechanisms for the epigenetic inheritance of stress response in single cells

(2018) Yuan Xue et al.   CURRENT GENETICS

Polymerase pausing induced by sequence-specific RNA-binding protein drives heterochromatin assembly

(2018) Jahan-Yar Parsa et al.   GENES & DEVELOPMENT

Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control

(2018) Pamela S. Gallagher et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Histone deacetylation promotes transcriptional silencing at facultative heterochromatin

(2018) Beth R Watts et al.   NUCLEIC ACIDS RESEARCH

The histone demethylase KDM6B regulates temperature-dependent sex determination in a turtle species

(2018) Chutian Ge et al.   SCIENCE

Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control

(2018) Pamela S. Gallagher et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability

(2018) Nahid Iglesias et al.   NATURE

Epigenetic fates of gene silencing established by heterochromatin spreading in cell identity and genome stability

(2018) R. A. Greenstein et al.   CURRENT GENETICS

Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin

(2018) Kehan Bao et al.   GENES & DEVELOPMENT

The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast

(2017) Hogyu David Seo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ten principles of heterochromatin formation and function

(2017) Robin C. Allshire et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family

(2017) Sneha Lal et al.   NUCLEIC ACIDS RESEARCH

Differential intron retention inJumonjichromatin modifier genes is implicated in reptile temperature-dependent sex determination

(2017) Ira W. Deveson et al.   Science Advances

The proper connection between shelterin components is required for telomeric heterochromatin assembly

(2016) Jiyong Wang et al.   GENES & DEVELOPMENT

Taz1-Shelterin Promotes Facultative Heterochromatin Assembly at Chromosome-Internal Sites Containing Late Replication Origins

(2016) Martin Zofall et al.   MOLECULAR CELL

Use ofade1andade2mutations for development of a versatile red/white colour assay of amyloid-induced oxidative stress insaccharomyces cerevisiae

(2016) Vidhya Bharathi et al.   YEAST

The Paf1 complex factors Leo1 and Paf1 promote local histone turnover to modulate chromatin states in fission yeast

(2015) L. Sadeghi et al.   EMBO REPORTS

The Paf1 complex represses small-RNA-mediated epigenetic gene silencing

(2015) Katarzyna Maria Kowalik et al.   NATURE

Histone exchange, chromatin structure and the regulation of transcription

(2015) Swaminathan Venkatesh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Restricted epigenetic inheritance of H3K9 methylation

(2015) P. N. C. B. Audergon et al.   SCIENCE

Global regulation of heterochromatin spreading by Leo1

(2015) L. Verrier et al.   Open Biology

Rapid epigenetic adaptation to uncontrolled heterochromatin spreading

(2015) Jiyong Wang et al.   eLife

lncRNA recruits RNAi and the exosome to dynamically regulate pho1 expression in response to phosphate levels in fission yeast

(2014) S. Shah et al.   GENES & DEVELOPMENT

Determinants of Heterochromatic siRNA Biogenesis and Function

(2014) Ruby Yu et al.   MOLECULAR CELL

Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex

(2014) E. D. Egan et al.   RNA

Epigenetic inheritance uncoupled from sequence-specific recruitment

(2014) K. Ragunathan et al.   SCIENCE

Mtr4-like Protein Coordinates Nuclear RNA Processing for Heterochromatin Assembly and for Telomere Maintenance

(2013) Nathan N. Lee et al.   CELL

HOW STABLE ‘SHOULD’ EPIGENETIC MODIFICATIONS BE? INSIGHTS FROM ADAPTIVE PLASTICITY AND BET HEDGING

(2013) Jacob J. Herman et al.   EVOLUTION

Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries

(2013) J. Wang et al.   GENES & DEVELOPMENT

Transcription-induced chromatin association of RNA surveillance factors mediates facultative heterochromatin formation in fission yeast

(2013) Sanki Tashiro et al.   GENES TO CELLS

HDAC-mediated suppression of histone turnover promotes epigenetic stability of heterochromatin

(2013) Ozan Aygün et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mmi1 RNA surveillance machinery directs RNAi complex RITS to specific meiotic genes in fission yeast

(2012) Edwige Hiriart et al.   EMBO JOURNAL

Telomere-binding protein Taz1 controls global replication timing through its localization near late replication origins in fission yeast

(2012) A. Tazumi et al.   GENES & DEVELOPMENT

RNAi triggered by specialized machinery silences developmental genes and retrotransposons

(2012) Soichiro Yamanaka et al.   NATURE

Hexanucleotide motifs mediate recruitment of the RNA elimination machinery to silent meiotic genes

(2012) A. Yamashita et al.   Open Biology

The Cul4-Ddb1Cdt2 Ubiquitin Ligase Inhibits Invasion of a Boundary-Associated Antisilencing Factor into Heterochromatin

(2011) Sigurd Braun et al.   CELL

Mechanism of CRL4Cdt2, a PCNA-dependent E3 ubiquitin ligase

(2011) C. G. Havens et al.   GENES & DEVELOPMENT

Chromodomain-Mediated Oligomerization of HP1 Suggests a Nucleosome-Bridging Mechanism for Heterochromatin Assembly

(2011) Daniele Canzio et al.   MOLECULAR CELL

PKA-dependent regulation of the histone lysine demethylase complex PHF2–ARID5B

(2011) Atsushi Baba et al.   NATURE CELL BIOLOGY

Targeting the epigenome for treatment of cancer

(2011) E-J Geutjes et al.   ONCOGENE

RNA Elimination Machinery Targeting Meiotic mRNAs Promotes Facultative Heterochromatin Formation

(2011) M. Zofall et al.   SCIENCE

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

Genomic Binding Profiling of the Fission Yeast Stress-Activated MAPK Sty1 and the bZIP Transcriptional Activator Atf1 in Response to H2O2

(2010) Majid Eshaghi et al.   PLoS One

Phosphorylation of Swi6/HP1 regulates transcriptional gene silencing at heterochromatin

(2009) A. Shimada et al.   GENES & DEVELOPMENT

Diverse roles of HP1 proteins in heterochromatin assembly and functions in fission yeast

(2009) T. Fischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cohesin Complex Promotes Transcriptional Termination between Convergent Genes in S. pombe

(2008) Monika Gullerova et al.   CELL

HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Nonoverlapping Mechanisms

(2008) Mohammad R. Motamedi et al.   MOLECULAR CELL