LILRB4 ITIMs mediate the T cell suppression and infiltration of acute myeloid leukemia cells

Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development

(2019) Xun Gui et al.   Cancer Immunology Research

A Novel Anti-LILRB4 CAR-T Cell for the Treatment of Monocytic AML

(2018) Samuel John et al.   MOLECULAR THERAPY

LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration

(2018) Mi Deng et al.   NATURE

A dual positive and negative regulation of monocyte activation by leukocyte Ig-like receptor B4 depends on the position of the tyrosine residues in its ITIMs

(2017) Mijeong Park et al.   Innate Immunity

ILT3.Fc–CD166 Interaction Induces Inactivation of p70 S6 Kinase and Inhibits Tumor Cell Growth

(2017) Zheng Xu et al.   JOURNAL OF IMMUNOLOGY

Inhibitory leukocyte immunoglobulin-like receptors: Immune checkpoint proteins and tumor sustaining factors

(2015) Xunlei Kang et al.   CELL CYCLE

Surveillance of cell and tissue perturbation by receptors in the LRC

(2015) John Trowsdale et al.   IMMUNOLOGICAL REVIEWS

Human CD43+ B cells are closely related not only to memory B cells phenotypically but also to plasmablasts developmentally in healthy individuals

(2015) Masanori Inui et al.   INTERNATIONAL IMMUNOLOGY

Functional and genetic diversity of leukocyte immunoglobulin-like receptor and implication for disease associations

(2015) Kouyuki Hirayasu et al.   JOURNAL OF HUMAN GENETICS

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

(2015) Zhengshan Chen et al.   NATURE

The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development

(2015) Xunlei Kang et al.   NATURE CELL BIOLOGY

Tregitope: Immunomodulation Powerhouse

(2014) Leslie Cousens et al.   HUMAN IMMUNOLOGY

Expression of immune inhibitory receptor ILT3 in acute myeloid leukemia with monocytic differentiation

(2012) Hanna Dobrowolska et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

(2012) Junke Zheng et al.   NATURE

Apolipoprotein E Induces Antiinflammatory Phenotype in Macrophages

(2011) Daniel Baitsch et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of PIR-B in Autoimmune Glomerulonephritis

(2010) Toshiyuki Takai et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

A dual activation and inhibition role for the paired immunoglobulin-like receptor B in eosinophils

(2008) A. Munitz et al.   BLOOD

Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future

(2008) Marc Daëron et al.   IMMUNOLOGICAL REVIEWS