Functional and genetic diversity of leukocyte immunoglobulin-like receptor and implication for disease associations

Identification of Susceptibility Loci inIL6,RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study

(2015) Paul A. Renauer et al.   Arthritis & Rheumatology

A motif in LILRB2 critical for Angptl2 binding and activation

(2014) M. Deng et al.   BLOOD

CKM and LILRB5 Are Associated With Serum Levels of Creatine Kinase

(2014) M.-P. Dube et al.   Circulation-Cardiovascular Genetics

Ig-Like Transcript 4 Inhibits Lipid Antigen Presentation through Direct CD1d Interaction

(2014) D. Li et al.   JOURNAL OF IMMUNOLOGY

Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue

(2014) K. R. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection

(2014) Arman A. Bashirova et al.   PLoS Genetics

Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair

(2013) Arman A. Bashirova et al.   IMMUNOGENETICS

Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors

(2013) María R. López-Álvarez et al.   IMMUNOGENETICS

Ig-like Transcript 7, but Not Bone Marrow Stromal Cell Antigen 2 (Also Known as HM1.24, Tetherin, or CD317), Modulates Plasmacytoid Dendritic Cell Function in Primary Human Blood Leukocytes

(2013) B. Tavano et al.   JOURNAL OF IMMUNOLOGY

Human LilrB2 Is a  -Amyloid Receptor and Its Murine Homolog PirB Regulates Synaptic Plasticity in an Alzheimer's Model

(2013) T. Kim et al.   SCIENCE

Contribution of FunctionalLILRA3, but Not NonfunctionalLILRA3, to Sex Bias in Susceptibility and Severity of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis

(2013) Yan Du et al.   Arthritis & Rheumatology

Functional genetic polymorphisms in ILT3 are associated with decreased surface expression on dendritic cells and increased serum cytokines in lupus patients

(2012) Mark A Jensen et al.   ANNALS OF THE RHEUMATIC DISEASES

6.7-kbp deletion in LILRA3 (ILT6) gene is associated with later onset of the multiple sclerosis in a Polish population

(2012) Andrzej Wiśniewski et al.   HUMAN IMMUNOLOGY

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

(2012) Junke Zheng et al.   NATURE

Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

(2012) Jianfeng Xu et al.   NATURE GENETICS

LILRA2 Selectively Modulates LPS-Mediated Cytokine Production and Inhibits Phagocytosis by Monocytes

(2012) Hao K. Lu et al.   PLoS One

HLA Class I Allelic Sequence and Conformation Regulate Leukocyte Ig-Like Receptor Binding

(2011) D. C. Jones et al.   JOURNAL OF IMMUNOLOGY

LILRA3 Binds Both Classical and Non-Classical HLA Class I Molecules but with Reduced Affinities Compared to LILRB1/LILRB2: Structural Evidence

(2011) Myongchol Ryu et al.   PLoS One

Expression of activating and inhibitory leukocyte immunoglobulin-like receptors in rheumatoid synovium: correlations to disease activity

(2011) N. Tedla et al.   TISSUE ANTIGENS

Immunization with Dendritic Cells Pulsed ex vivo with Recombinant Chlamydial Protease-Like Activity Factor Induces Protective Immunity Against Genital Chlamydiamuridarum Challenge

(2011) Weidang Li et al.   Frontiers in Immunology

LILRB1 polymorphism and surface phenotypes of natural killer cells

(2010) Chelsea L. Davidson et al.   HUMAN IMMUNOLOGY

Membrane and Soluble ILT3 Are Critical to the Generation of T Suppressor Cells and Induction of Immunological Tolerance

(2010) George Vlad et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Soluble LILRA3, a Potential Natural Antiinflammatory Protein, Is Increased in Patients with Rheumatoid Arthritis and Is Tightly Regulated by Interleukin 10, Tumor Necrosis Factor- , and Interferon- 

(2010) H. AN et al.   JOURNAL OF RHEUMATOLOGY

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Diversity of Human Copy Number Variation and Multicopy Genes

(2010) Peter H. Sudmant et al.   SCIENCE

Association of immunoglobulin-like transcript 6 deficiency with Sjögren's syndrome

(2009) G. Kabalak et al.   ARTHRITIS AND RHEUMATISM

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients

(2009) K. Pfistershammer et al.   BLOOD

Alternative mRNA splicing creates transcripts encoding soluble proteins from mostLILRgenes

(2009) Des C. Jones et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Multiple sclerosis associates with LILRA3 deletion in Spanish patients

(2009) D Ordóñez et al.   GENES AND IMMUNITY

Inhibitory ITAMs as novel regulators of immunity

(2009) Ulrich Blank et al.   IMMUNOLOGICAL REVIEWS

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction

(2009) Wei Cao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crystal Structure of Myeloid Cell Activating Receptor Leukocyte Ig-like Receptor A2 (LILRA2/ILT1/LIR-7) Domain Swapped Dimer: Molecular Basis for Its Non-binding to MHC Complexes

(2009) Yong Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

Evidence for Natural Selection on Leukocyte Immunoglobulin-like Receptors for HLA Class I in Northeast Asians

(2008) Kouyuki Hirayasu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

(2008) M. Yawata et al.   BLOOD

LILRA5 is expressed by synovial tissue macrophages in rheumatoid arthritis, selectively induces pro-inflammatory cytokines and IL-10 and is regulated by TNF-α, IL-10 and IFN-γ

(2008) Ainslie Mitchell et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Association of LILRA2 (ILT1, LIR7) splice site polymorphism with systemic lupus erythematosus and microscopic polyangiitis

(2008) K Mamegano et al.   GENES AND IMMUNITY

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

Natural killer cell recognition of missing self

(2008) Klas Kärre   NATURE IMMUNOLOGY

PirB is a Functional Receptor for Myelin Inhibitors of Axonal Regeneration

(2008) J. K. Atwal et al.   SCIENCE