Article
Integrative & Complementary Medicine
Yinglian Song, Ke Fu, Dewei Zhang, Min Xu, Ruixia Wu, Xueqing Xiong, Xianwu Liu, Lei Wu, Ya Guo, You Zhou, Xiaoli Li, Zhang Wang
Summary: This study aimed to investigate the distribution of 18 elements in Tibetan medicine Qishiwei Zhenzhu pills in rats with cerebral ischemia. The results showed that the accumulation of these elements in blood and tissues was minimal, with the majority being excreted through feces within 24 hours, emphasizing the significance of the gut-microbiota-brain axis in QSW-mediated brain protection.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2021)
Article
Biochemical Research Methods
Xiao-mei Long, Rong Li, Hai-peng Liu, Zong-xiao Xia, Shuang Guo, Jian-xing Gu, Li-jun Zhang, Yuan Fan, Zu-kun Chen
Summary: This study proposed a methodology for quality control of Triphala (THL) based on HPLC fingerprinting combined with an orthogonal array design. Fingerprint analysis was performed on 20 batches of THL from different geographical areas, revealing a similarity greater than 0.9 and classifying the batches into two clusters. Four differential components of THL were identified using OPLS-DA. The optimal extraction conditions were a time of 30 min, a temperature of 90°C, and a solid-liquid ratio of 30 mL/g.
PHYTOCHEMICAL ANALYSIS
(2023)
Article
Environmental Sciences
Huiming Lin, Yindong Tong, Chenghao Yu, Long Chen, Xiufeng Yin, Qianggong Zhang, Shichang Kang, Lun Luo, James Schauer, Benjamin de Foy, Xuejun Wang
Summary: The transport of atmospheric pollutants from the Indian subcontinent to the Tibetan Plateau has influenced the Tibetan environments, particularly in the Nyingchi region. The study investigated the influence of the Indian summer monsoon on the behavior and origin of mercury in Nyingchi. Results showed that the concentration and sources of mercury varied between the preceding Indian summer monsoon period and the Indian summer monsoon period. The study also identified long-distance transport, local emissions, meteorological factors, and snowmelt factors as the main factors affecting the local mercury concentration in Nyingchi.
ATMOSPHERIC CHEMISTRY AND PHYSICS
(2022)
Article
Chemistry, Analytical
Brian B. Looney, Leigh W. Brown, Mark A. Jones, Thomas L. White
Summary: This study used DMA to analyze total mercury in radioactive waste samples and compared the results with CVAAS and ICPMS. The findings showed that all methods generated accurate total mercury data and equivalent precision, and DMA was found to be easier and more convenient to use in a radioactive environment.
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2022)
Article
Pharmacology & Pharmacy
Cen Li, Cuiying Niu, Hongtao Bi, Jing Zhao, Jorge Ivan Alvarez, Farong Yuan, Xiangyun Gai, Lixin Wei, Yuzhi Du, Yajun Qiao, Hania Kebir, Yuancan Xiao, Hongxia Yang
Summary: Zuotai exhibited the alleviation of depressive-like behaviors in CRS mice, accompanying with ameliorating stress hormone, peripherical and cerebral inflammation, and monoamine neurotransmitter.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Soil Science
Lubica Pospisilova, Peter Uhlik, Ladislav Mensik, Lukas Hlisnikovsky, Ales Eichmeier, Eva Horakova, Vitezslav Vlcek
Summary: The study investigated the mineral transformation in the profile of recent soil developed on loess in Litovelske Pomoravi, highlighting the significant differences between argic horizons and other soil horizons. The research identified the presence of new hydroxy-interlayered minerals as a result of illite (vermiculite) weathering in humid continental conditions. The analysis also showed an increase in smectites, dioctahedral micas, and goethite due to the clay illuviation/lessivage process.
EUROPEAN JOURNAL OF SOIL SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Didi Ma, Lijun Wang, Yibao Jin, Lifei Gu, Xiean Yu, Xueqing Xie, Guo Yin, Jue Wang, Kaishun Bi, Yi Lu, Tiejie Wang
Summary: By using UHPLC fingerprints and chemical pattern recognition analysis, an accurate classification method for Rhodiola crenulate, Rhodiola rosea, and other confusable species was established. Linear discriminant analysis (LDA) combined with stepwise feature selection exhibited effective discrimination, providing useful information for authentic identification of characteristic peaks.
Article
Environmental Sciences
Huiming Lin, Yindong Tong, Long Chen, Chenghao Yu, Zhaohan Chu, Qianru Zhang, Xiufeng Yin, Qianggong Zhang, Shichang Kang, Junfeng Liu, James Schauer, Benjamin de Foy, Xuejun Wang
Summary: This study conducted continuous monitoring of atmospheric mercury (Hg) species in Lhasa, Tibet. The results showed that during the Indian summer monsoon (S-ISM) period, the concentrations of gaseous elemental Hg (GEM), gaseous oxidized Hg (GOM), and particle-bound Hg (PBM) were relatively high. Combustion events were identified as the main contributor to the high Hg concentration events in the city.
ATMOSPHERIC CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Analytical
Xiaoxia Xue, Runa Jin, Qishu Jiao, Xiwen Li, Pengyue Li, Gang Shen, Shougang Shi, Zhengjun Huang, Shuosheng Zhang, Yuntao Dai
Summary: This study developed holistic and practical quality evaluation methods to chemically distinguish three common Asparagus species in markets. The chemical constituents of the species were rapidly tentatively annotated using UHPLC-LTQ-Orbitrap-MS and MN. In addition, fingerprint analysis and content determination were performed using HPLC-ELSD. This study provides feasible quality evaluation methods for Asparagus species.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Review
Engineering, Chemical
Congnan Peng, Liping Kang, Xin Yuan, Jiaqi Qiao, Yilin Fan, Li Yao, Kailin Qi, Yaxuan Sun, Xueling Dai, Yuan Zhang, Qing Huo
Summary: This study summarizes the chemical status of mercury in bulk Chinese medicinal herbs and traditional Chinese medicine preparations, discusses the research methods for their analysis, and improves the analytical methods and evaluation standards for the chemical state of mercury in Chinese herbal medicines.
Article
Plant Sciences
Tran Viet Hung, Phan Nguyen Truong Thang, Ha Minh Hien, Vu Thi Diep, Nguyen Thi Thu, Duong Minh Tan, Duy Toan Pham, Do Thi Ha, Duyen Thi My Huynh
Summary: In this study, the fingerprint profiles of different strains of Ganoderma lucidum and related species were analyzed using HPTLC, and significant differences in triterpene derivatives were observed. The cytotoxicity evaluation showed that these samples exhibited varying levels of cytotoxic effects against different cancer cell lines.
Article
Biochemistry & Molecular Biology
Yuanyuan Jiang, Hongfei Wu, Paul Chi Lui Ho, Xuemei Tang, Hui Ao, Lu Chen, Jinjin Cai
Summary: This study successfully developed a strategy combining gas chromatography-mass spectrometry (GC-MS) fingerprints and chemical pattern recognition to identify two seahorse species, and discovered chemical markers that can differentiate between them. This study holds significant importance for the identification of seahorses and the conservation of wild seahorse resources.
Article
Chemistry, Multidisciplinary
I Cmelo, M. Vorsilak, D. Svozil
Summary: The use of pointwise mutual information (PMI) to characterize the association strength between compound structural features in publicly available databases validates the effectiveness of this analysis method. The derived Z-standardized relative feature tightness (ZRFT) values not only accurately differentiate between compounds with different synthetic accessibility levels, but also contain information relevant to the physico-chemical properties of organic compounds. This suggests that structural feature co-occurrence quantified by PMI or ZRFT is significant in understanding compound properties.
JOURNAL OF CHEMINFORMATICS
(2021)
Article
Biochemical Research Methods
Meiqi Liu, Xiaoran Zhao, Zicheng Ma, Ziying Qiu, Lili Sun, Meng Wang, Xiaoliang Ren, Yanru Deng
Summary: A new strategy was developed to discover potential quality markers (Q-markers) of traditional Chinese medicines (TCMs) by integrating chemometrics, network pharmacology, and molecular docking. This strategy could be used to evaluate overall chemical consistency of TCMs.
PHYTOCHEMICAL ANALYSIS
(2022)
Article
Medicine, Research & Experimental
Jinyan Cai, Jingjing Zhang, Shanshan Li, Yanduan Lin, Xue Xiao, Jiao Guo
Summary: The study comprehensively revealed the compositions of Zhenshu TiaoZhi formula and demonstrated its effects on improving glucolipid metabolism, suggesting that down regulating 11 beta-HSD1 in insulin-sensitive tissues may be a potential mechanism of FTZ in treating type 2 diabetes mellitus.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Chemistry, Applied
Hailiang Wang, Tingting Gao, Yuzhi Du, Hongxia Yang, Lixin Wei, Hongtao Bi, Weihua Ni
CARBOHYDRATE POLYMERS
(2015)
Article
Biochemistry & Molecular Biology
Mengqi Xu, Lixin Wei, Yuancan Xiao, Hongtao Bi, Hongxia Yang, Yuzhi Du
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2017)
Article
Food Science & Technology
Mengqi Xu, Lixin Wei, Yuancan Xiao, Hongtao Bi, Hongxia Yang, Yuzhi Du
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
(2017)
Article
Biochemistry & Molecular Biology
Ming Zhang, Jianbin Ma, Hongtao Bi, Jiayin Song, Hongxia Yang, Zhenghua Xia, Yuzhi Du, Tingting Gao, Lixin Wei
Article
Biochemistry & Molecular Biology
Ming Zhang, Hongtao Bi, Cen Li, Yuzhi Du, Lixin Wei
BIOLOGICAL TRACE ELEMENT RESEARCH
(2018)
Article
Biochemistry & Molecular Biology
Xiaojuan Huang, Jianbin Ma, Lixin Wei, Jiayin Song, Cen Li, Hongxia Yang, Yuzhi Du, Tingting Gao, Hongtao Bi
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
Article
Biochemistry & Molecular Biology
Hailiang Wang, Hongtao Bi, Tingting Gao, Bin Zhao, Weihua Ni, Jun Liu
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
Article
Pharmacology & Pharmacy
Qiaozhu Tan, Zhitao Liu, Hong Li, Yongjun Liu, Zhenghua Xia, Yuancan Xiao, Muhammad Usman, Yuzhi Du, Hongtao Bi, Lixin Wei
Article
Pharmacology & Pharmacy
Qiaozhu Tan, Ming Zhang, Lujing Geng, Zhenghua Xia, Cen Lia, Muhammad Usman, Yuzhi Du, Lixin Wei, Hongtao Bi
TOXICOLOGY AND APPLIED PHARMACOLOGY
(2019)
Article
Integrative & Complementary Medicine
Yuancan Xiao, Cen Li, Wei Xu, Yuzhi Du, Ming Zhang, Hongxia Yang, Lixin Wei, Hongtao Bi
Summary: Research has found that arsenic in wild Cordyceps sinensis mainly exists in trivalent and pentavalent forms, and arsenic accumulates primarily in the digestive tract of the host larva.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Xingfang Zhang, Yajun Qiao, Mengyuan Wang, Xinxin Liang, Ming Zhang, Cen Li, Jixian Cairang, Jianv Wang, Hongtao Bi, Tingting Gao
Summary: Depression is a common mental disorder with a significant impact worldwide, resulting in numerous deaths. The causes of depression can be categorized into congenital genetic factors and acquired environmental factors. These factors include genetic mutations, birth patterns, feeding patterns, dietary patterns, childhood experiences, education and economic levels, isolation due to epidemics, and other complex factors. Research has shown that both innate and acquired factors play important roles in the occurrence of depression. Understanding these factors can provide new insights and approaches for the prevention and treatment of depression.
BIOSCIENCE REPORTS
(2023)
Article
Plant Sciences
Xingfang Zhang, Mengyuan Wang, Xinxin Liang, Jianv Wang, Ming Zhang, Cen Li, Lixin Wei, Hongtao Bi
Summary: This study used bioinformatics and in vivo experimental validation to investigate the potential role of Ophiocordyceps sinensis in the treatment of lung adenocarcinoma (LUAD). The study identified BRCA1 and CCNE1 as important biomarkers and core targets of O. sinensis against LUAD. The results suggest that O. sinensis has inhibitory effects on LUAD through specific signaling pathways.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Cen Li, Cuiying Niu, Hongtao Bi, Jing Zhao, Jorge Ivan Alvarez, Farong Yuan, Xiangyun Gai, Lixin Wei, Yuzhi Du, Yajun Qiao, Hania Kebir, Yuancan Xiao, Hongxia Yang
Summary: Zuotai exhibited the alleviation of depressive-like behaviors in CRS mice, accompanying with ameliorating stress hormone, peripherical and cerebral inflammation, and monoamine neurotransmitter.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Lujing Geng, Zhenghua Xia, Lu Yuan, Cen Li, Ming Zhang, Yuzhi Du, Lixin Wei, Hongtao Bi