“Trim”ming PolyQ proteins with engineered PML

Tripartite motif proteins: an emerging antiviral protein family

(2019) Girish Patil et al.   Future Virology

Proteostasis in Huntington's disease: disease mechanisms and therapeutic opportunities

(2018) Rachel J Harding et al.   ACTA PHARMACOLOGICA SINICA

Twenty-five years since the identification of the first SCA gene: history, clinical features and perspectives for SCA1

(2018) Carlos Roberto Martins Junior et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation

(2017) William A. McEwan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced protein degradation: an emerging drug discovery paradigm

(2016) Ashton C. Lai et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genes

(2015) Olga Sin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Antibodies and protein misfolding: From structural research tools to therapeutic strategies

(2014) Erwin De Genst et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Polyglutamine (PolyQ) Diseases: Genetics to Treatments

(2014) Hueng-Chuen Fan et al.   CELL TRANSPLANTATION

Ubiquibodies, Synthetic E3 Ubiquitin Ligases Endowed with Unnatural Substrate Specificity for Targeted Protein Silencing

(2014) Alyse D. Portnoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cellular System that Degrades Misfolded Proteins and Protects against Neurodegeneration

(2014) Lili Guo et al.   MOLECULAR CELL

The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution

(2014) Nico P. Dantuma et al.   Frontiers in Molecular Neuroscience

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

(2012) A. Gurney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Fluorescent fusion protein knockout mediated by anti-GFP nanobody

(2011) Emmanuel Caussinus et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

TRIM5  Disrupts the Structure of Assembled HIV-1 Capsid Complexes In Vitro

(2010) L. R. Black et al.   JOURNAL OF VIROLOGY

Monoclonal Antibodies Recognize Distinct Conformational Epitopes Formed by Polyglutamine in a Mutant Huntingtin Fragment

(2009) Justin Legleiter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Targeting of Fibrillar Polyglutamine Proteins in Live Cells Escalates Aggregation and Cytotoxicity

(2009) Erik Kvam et al.   PLoS One

Pathogenic Mechanisms of a Polyglutamine-mediated Neurodegenerative Disease, Spinocerebellar Ataxia Type 1

(2008) Huda Y. Zoghbi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY