Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks

Androgen Deprivation Therapy and Future Alzheimer’s Disease Risk

(2016) Kevin T. Nead et al.   JOURNAL OF CLINICAL ONCOLOGY

EHDViz: clinical dashboard development using open-source technologies

(2016) Marcus A Badgeley et al.   BMJ Open

Systematic Assessment of the Correlations of Household Income With Infectious, Biochemical, Physiological, and Environmental Factors in the United States, 1999–2006

(2015) Chirag J. Patel et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Computational and Experimental Advances in Drug Repositioning for Accelerated Therapeutic Stratification

(2015) Khader Shameer et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Introduction: Table 1

(2015)   DIABETES CARE

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

(2015) Yun R Li et al.   NATURE MEDICINE

Racial and Ethnic Disparities in Hospital Readmissions After Delivery

(2015) Robert H. Aseltine et al.   OBSTETRICS AND GYNECOLOGY

Sex and Racial/Ethnic Differences in Premature Mortality Due to HIV: Florida, 2000–2009

(2015) Mary Jo Trepka et al.   PUBLIC HEALTH REPORTS

Identification of type 2 diabetes subgroups through topological analysis of patient similarity

(2015) Li Li et al.   Science Translational Medicine

Disease Risk Factors Identified Through Shared Genetic Architecture and Electronic Medical Records

(2014) L. Li et al.   Science Translational Medicine

Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients

(2014) Anders Boeck Jensen et al.   Nature Communications

Human symptoms–disease network

(2014) XueZhong Zhou et al.   Nature Communications

Detection of Pleiotropy through a Phenome-Wide Association Study (PheWAS) of Epidemiologic Data as Part of the Environmental Architecture for Genes Linked to Environment (EAGLE) Study

(2014) Molly A. Hall et al.   PLoS Genetics

Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis

(2014) Bahram Namjou et al.   Frontiers in Genetics

A Nondegenerate Code of Deleterious Variants in Mendelian Loci Contributes to Complex Disease Risk

(2013) David R. Blair et al.   CELL

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

(2013) Khader Shameer et al.   HUMAN GENETICS

Topological analysis and interactive visualization of biological networks and protein structures

(2012) Nadezhda T Doncheva et al.   Nature Protocols

Mining electronic health records: towards better research applications and clinical care

(2012) Peter B. Jensen et al.   NATURE REVIEWS GENETICS

Shared genetic architecture in the relationship between adult stature and subclinical coronary artery atherosclerosis

(2011) Andrea E. Cassidy-Bushrow et al.   ATHEROSCLEROSIS

Exploiting drug-disease relationships for computational drug repositioning

(2011) J. T. Dudley et al.   BRIEFINGS IN BIOINFORMATICS

Disease Ontology: a backbone for disease semantic integration

(2011) L. M. Schriml et al.   NUCLEIC ACIDS RESEARCH

Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease

(2011) J. T. Dudley et al.   Science Translational Medicine

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

(2010) J. C. Denny et al.   BIOINFORMATICS

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus

(2010) Chirag J. Patel et al.   PLoS One

Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

(2010) Silpa Suthram et al.   PLoS Computational Biology

Diabetes in African American Youth: Prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study

(2009) E. J. Mayer-Davis et al.   DIABETES CARE

A network medicine approach to human disease

(2009) Andreas Zanzoni et al.   FEBS LETTERS

A network view of disease and compound screening

(2009) Eric E. Schadt et al.   NATURE REVIEWS DRUG DISCOVERY

Phenomics: the systematic study of phenotypes on a genome-wide scale

(2009) R.M. Bilder et al.   NEUROSCIENCE

A Dynamic Network Approach for the Study of Human Phenotypes

(2009) César A. Hidalgo et al.   PLoS Computational Biology

Network properties of genes harboring inherited disease mutations

(2008) I. Feldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The implications of human metabolic network topology for disease comorbidity

(2008) D.- S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA