A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk

(2013) Marylyn D. Ritchie et al.   CIRCULATION

A PheWAS approach in studying HLA-DRB1*1501

(2013) S J Hebbring et al.   GENES AND IMMUNITY

RNAi–Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function

(2013) Peter Blattmann et al.   PLoS Genetics

Linking disease associations with regulatory information in the human genome

(2012) M. A. Schaub et al.   GENOME RESEARCH

Chromatin marks identify critical cell types for fine mapping complex trait variants

(2012) Gosia Trynka et al.   NATURE GENETICS

Novel Associations for Hypothyroidism Include Known Autoimmune Risk Loci

(2012) Nicholas Eriksson et al.   PLoS One

A Meta-Analysis and Genome-Wide Association Study of Platelet Count and Mean Platelet Volume in African Americans

(2012) Rehan Qayyum et al.   PLoS Genetics

Variants Near FOXE1 Are Associated with Hypothyroidism and Other Thyroid Conditions: Using Electronic Medical Records for Genome- and Phenome-wide Studies

(2011) Joshua C. Denny et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies

(2011) Catherine A McCarty et al.   BMC Medical Genomics

Platelets Alter Tumor Cell Attributes to Propel Metastasis: Programming in Transit

(2011) Laurie J. Gay et al.   CANCER CELL

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Mapping Rare and Common Causal Alleles for Complex Human Diseases

(2011) Soumya Raychaudhuri   CELL

The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery

(2011) S.A. Pendergrass et al.   GENETIC EPIDEMIOLOGY

The genetics of common variation affecting platelet development, function and pharmaceutical targeting

(2011) A. D. JOHNSON   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

New gene functions in megakaryopoiesis and platelet formation

(2011) Christian Gieger et al.   NATURE

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

Large Scale Association Analysis Identifies Three Susceptibility Loci for Coronary Artery Disease

(2011) Stephanie Saade et al.   PLoS One

Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits

(2011) Dirk S. Paul et al.   PLoS Genetics

Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis

(2010) A. Hinks et al.   ANNALS OF THE RHEUMATIC DISEASES

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

(2010) J. C. Denny et al.   BIOINFORMATICS

The genetics of normal platelet reactivity

(2010) T. J. Kunicki et al.   BLOOD

The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis

(2010) A Alcina et al.   GENES AND IMMUNITY

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Determinants of platelet count in humans

(2010) M. E. Daly   HAEMATOLOGICA

Cytoskeletal mechanics of proplatelet maturation and platelet release

(2010) Jonathan N. Thon et al.   JOURNAL OF CELL BIOLOGY

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

(2010) Samuli Ripatti et al.   LANCET

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

A Genome-Wide Association Study of Red Blood Cell Traits Using the Electronic Medical Record

(2010) Iftikhar J. Kullo et al.   PLoS One

Sequence Variants in Three Loci Influence Monocyte Counts and Erythrocyte Volume

(2009) Manuel A.R. Ferreira et al.   AMERICAN JOURNAL OF HUMAN GENETICS

From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations

(2009) P. Du et al.   BIOINFORMATICS

The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells

(2009) K. Wahlberg et al.   BLOOD

A HaemAtlas: characterizing gene expression in differentiated human blood cells

(2009) Nicholas A. Watkins et al.   BLOOD

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

(2009) N. Soranzo et al.   BLOOD

Platelet α-granules: Basic biology and clinical correlates

(2009) Price Blair et al.   BLOOD REVIEWS

Importance of platelets and platelet response in acute coronary syndromes

(2009) K. KOTTKE-MARCHANT   CLEVELAND CLINIC JOURNAL OF MEDICINE

Genetics of platelet reactivity in normal, healthy individuals

(2009) T. J. KUNICKI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet functions beyond hemostasis

(2009) S. S. SMYTH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

(2009) Daniel F Gudbjartsson et al.   NATURE GENETICS

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

(2009) Nicole Soranzo et al.   NATURE GENETICS

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS

A Genome-wide Association Study Identifies Three Loci Associated with Mean Platelet Volume

(2008) Christa Meisinger et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mean platelet volume (MPV) as an inflammatory marker in ankylosing spondylitis and rheumatoid arthritis

(2008) Bunyamin Kisacik et al.   JOINT BONE SPINE

Newly identified genetic risk variants for celiac disease related to the immune response

(2008) Karen A Hunt et al.   NATURE GENETICS

Platelets, Petechiae, and Preservation of the Vascular Wall

(2008) Ralph L. Nachman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reactome knowledgebase of human biological pathways and processes

(2008) L. Matthews et al.   NUCLEIC ACIDS RESEARCH