Genistein regulates tumor microenvironment and exhibits anticancer effect in dimethyl hydrazine-induced experimental colon carcinogenesis

New horizons in tumor microenvironment biology: challenges and opportunities

(2015) Fei Chen et al.   BMC Medicine

Dietary cocoa protects against colitis-associated cancer by activating the Nrf2/Keap1 pathway

(2014) Ashok Kumar Pandurangan et al.   BIOFACTORS

Colorectal cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression

(2014) Shakir M. Saud et al.   CARCINOGENESIS

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Genistein-Inhibited Cancer Stem Cell-Like Properties and Reduced Chemoresistance of Gastric Cancer

(2014) Weifeng Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Picrosirius Red Staining

(2014) Raed Lattouf et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells

(2013) H Hirata et al.   BRITISH JOURNAL OF CANCER

Naringin accelerates the regression of pre-neoplastic lesions and the colorectal structural reorganization in a murine model of chemical carcinogenesis

(2013) Priscila L. Sequetto et al.   FOOD AND CHEMICAL TOXICOLOGY

Luteolin, a bioflavonoid inhibits Azoxymethane-induced colorectal cancer through activation of Nrf2 signaling

(2013) Ashok Kumar Pandurangan et al.   TOXICOLOGY MECHANISMS AND METHODS

Collagen as a double-edged sword in tumor progression

(2013) Min Fang et al.   TUMOR BIOLOGY

Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway

(2013) Panhong Fan et al.   Stem Cell Research & Therapy

Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/β-catenin signalling and reduces colon pre-neoplasia in rats

(2012) Yukun Zhang et al.   BRITISH JOURNAL OF NUTRITION

Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog–Gli1 pathway

(2012) Linlin Zhang et al.   CANCER LETTERS

Cancer stem cells and their potential implications for the treatment of solid tumors

(2012) B.A. Grotenhuis et al.   JOURNAL OF SURGICAL ONCOLOGY

Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells

(2012) Xiaohan Zhai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Naringin modulates oxidative stress and inflammation in 3-nitropropionic acid-induced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway

(2012) K. Gopinath et al.   NEUROSCIENCE

Molecular Genetics of Colorectal Cancer

(2011) Eric R. Fearon   Annual Review of Pathology-Mechanisms of Disease

Ellagic acid prevents rat colon carcinogenesis induced by 1, 2 dimethyl hydrazine through inhibition of AKT-phosphoinositide-3 kinase pathway

(2011) Syed Umesalma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Genistein attenuates WNT signaling by up-regulating sFRP2 in a human colon cancer cell line

(2011) Yukun Zhang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Pterostilbene Is More Potent than Resveratrol in Preventing Azoxymethane (AOM)-Induced Colon Tumorigenesis via Activation of the NF-E2-Related Factor 2 (Nrf2)-Mediated Antioxidant Signaling Pathway

(2011) Yi-Siou Chiou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Flavonoids: Potential Wnt/beta-catenin signaling modulators in cancer

(2011) Nathália G. Amado et al.   LIFE SCIENCES

Colon Cancer Stem Cells: Promise of Targeted Therapy

(2010) Matilde Todaro et al.   GASTROENTEROLOGY

Morphological and Molecular Alterations in 1,2 Dimethylhydrazine and Azoxymethane Induced Colon Carcinogenesis in Rats

(2010) Martina Perše et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Suppression of Colonic Aberrant Crypt Foci by Soy Isoflavones Is Dose-Independent in Dimethylhydrazine-Treated Rats

(2010) Won-Kyung Min et al.   JOURNAL OF MEDICINAL FOOD

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Combination of aging and dimethylhydrazine treatment causes an increase in cancer—stem cell population of rat colonic crypts

(2009) Edi Levi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells

(2009) S C Kirkland   BRITISH JOURNAL OF CANCER

Human colon tissue in organ culture: preservation of normal and neoplastic characteristics

(2009) Michael K. Dame et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/ β-catenin pathway

(2009) Pandurangan Ashokkumar et al.   INVESTIGATIONAL NEW DRUGS

Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2

(2009) Ponnuraj Nagendraprabhu et al.   INVESTIGATIONAL NEW DRUGS

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis of Colorectal Cancer

(2009) Sanford D. Markowitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protective role of luteolin on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis

(2008) Pandurangan Ashokkumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2–Keap1 signaling

(2008) Narayanan Sriram et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS