Article
Food Science & Technology
Yarsmin Yunus Zeebone, Brigitta Bota, Veronika Halas, Balazs Libisch, Ferenc Olasz, Peter Papp, Tibor Kereszteny, Annamaria Gerocs, Omeralfaroug Ali, Melinda Kovacs, Andras Szabo
Summary: This study investigated the effects of dietary fumonisins on the gut and faecal microbiota of weaned pigs. Results showed no effects on growth performance, but there were changes in serum enzyme activities and alterations in microbial populations in the duodenum, ileum, and faeces. The study suggests that a high dosage of fumonisins can alter the gut microbiota of pigs without affecting their growth performance.
Article
Agriculture, Dairy & Animal Science
Hyunjin Kyoung, Jeong Jae Lee, Jin Ho Cho, Jeehwan Choe, Joowon Kang, Hanbae Lee, Yanhong Liu, Younghoon Kim, Hyeun Bum Kim, Minho Song
Summary: Dietary glutamic acid can influence the growth performance and health of weaned pigs by modulating nutrient digestibility, intestinal morphology, ileal gene expression of tight junction proteins and cytokines, immune responses, and microbial community in the gut.
Article
Microbiology
Jiali Chen, Zhicheng Song, Rongmei Ji, Yongxu Liu, Hong Zhao, Lei Liu, Fuchang Li
Summary: The study demonstrated that dietary supplementation with 800 mg/kg chlorogenic acid can significantly improve the growth performance of weaned rabbits by enhancing intestinal structural integrity, improving intestinal epithelium function, and modulating gut microbiota composition and diversity.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Hongshan Li, Yingfei Xi, Xin Xin, Qin Feng, Yiyang Hu
Summary: This study found that geniposide and chlorogenic acid, the main active ingredients in Yinchenhao Decoction, can improve non-alcoholic steatohepatitis (NASH) in mice by improving the gut microbiome and activating the FXR signaling pathway.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Microbiology
Mengmeng Mi, Zhiwen Shen, Nianzhi Hu, Qiyu Zhang, Bin Wang, Li Pan, Guixin Qin, Nan Bao, Yuan Zhao
Summary: This study aimed to investigate the effects of diets with different amino acid release characteristics on intestinal barrier function and gut microbiota diversity in weaned pigs. The results showed that casein and mixed diets, which had a more balanced release of amino acids compared to corn gluten meal, resulted in lower diamine oxidase concentrations and maintained intestinal barrier function, while also increasing gut microbiota diversity. These findings provide a scientific reference for the rational preparation of piglet feed.
Article
Endocrinology & Metabolism
Xiaolin Ye, Yang Liu, Jiajin Hu, Yanyan Gao, Yanan Ma, Deliang Wen
Summary: This study investigated the effects of chlorogenic acid (CGA) found in coffee on obesity and metabolic endotoxemia. CGA was found to prevent weight gain, improve intestinal barrier function, and prevent metabolic disorders and endotoxemia through altering the gut microbiota composition. The study concludes that CGA-induced changes in the gut microbiota play a key role in inhibiting metabolic endotoxemia in high-fat diet-fed mice.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Min Song, Fenglin Zhang, Lin Chen, Qiang Yang, Han Su, Xiaohua Yang, Haiwen He, Mingfa Ling, Jisong Zheng, Chen Duan, Xumin Lai, Mushui Pan, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
Summary: CDCA supplementation improved the growth performance of weaned piglets by enhancing intestinal morphology and barrier function, enhancing lipid digestion, altering serum metabolic profiles, and changing the relative abundance of certain gut bacteria.
Article
Biochemistry & Molecular Biology
G. Balaj, Z. Tamanai-Shacoori, D. Olivier-Jimenez, A. Sauvager, M. Faustin, L. Bousarghin, S. David-Le Gall, S. Guyot, D. Nebija, S. Tomasi, M. L. Abasq
Summary: Microbiota plays a key role in metabolizing dietary polyphenols, and this study found that a gut bacterium, L. reuteri, is able to convert 5-CQA into various metabolites, including the previously unknown compound esculetin. This oxidative pathway occurring in vivo may have beneficial effects on the gut microbiota and should be further studied.
Article
Agriculture, Dairy & Animal Science
Natalie E. Diether, Seo Lin Nam, Janelle Fouhse, Bich Le Thanh, Paul Stothard, Ruurd T. Zijlstra, James Harynuk, Paulina de la Mata, Benjamin P. Willing
Summary: Addition of benzoic acid and enzymes in pig diets can impact gut microbiota and metabolome, potentially supporting health and reducing diarrhea incidence in weaned pigs.
JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
F. Correa, D. Luise, L. Amatucci, F. Palumbo, S. Virdis, C. Negrini, P. Clavenzani, M. Vecchi, M. Mazzoni, P. Bosi, P. Trevisi
Summary: The study aimed to determine the effect of an oral vaccine against Escherichia coli F4 and F18 on gut functionality, growth performance, and health status of postweaning piglets. The results showed that the oral vaccine can promote gut health by controlling postweaning symptoms and has a probiotic-like effect by modulating gut microbiota.
Article
Agriculture, Dairy & Animal Science
F. Correa, D. Luise, G. Palladino, D. Scicchitano, P. Brigidi, P. L. Martelli, G. Babbi, S. Turroni, G. Litta, M. Candela, S. Rampelli, P. Trevisi
Summary: Body lesions in weaned pigs can lead to pain, infection, and impaired mobility, affecting growth and survival. Weaning stress can also impact gut microbiota, immune response, and oxidative stress. This study examines the relationship between body lesions, oxidative stress, and gut microbiota in weaned pigs.
Article
Agriculture, Dairy & Animal Science
Ju Kyoung Oh, Robie Vasquez, Sang Hoon Kim, In-Chan Hwang, Ji Hoon Song, Jae Hong Park, In Ho Kim, Dae-Kyung Kang
Summary: Supplementation with multispecies probiotics significantly increased fecal concentrations of lactate, acetate, and formate, altered the gut microbiota by increasing potentially beneficial bacteria and decreasing pathogenic bacteria in weaned pigs. The modulation of the gut microbiota was strongly correlated with changes in fecal SCFAs and lactate levels, supporting the potential use of MSPs to improve gut health in animals.
JOURNAL OF ANIMAL SCIENCE AND TECHNOLOGY
(2021)
Article
Veterinary Sciences
Qinglei Xu, Meng Cheng, Rong Jiang, Xianle Zhao, Jianjin Zhu, Mingzheng Liu, Xiaohuan Chao, Chunlei Zhang, Bo Zhou
Summary: This study evaluated the effects of a Chinese herbal mixture on the growth performance, immune response, antioxidant capacity, and intestinal microbiota of weaned pigs. The results showed that the herbal mixture improved growth performance, immunity, and antioxidant capacity, and modified the composition of intestinal microbiota in weaning pigs.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Opeyemi O. O. Adekolurejo, Katie McDermott, Henry M. R. Greathead, Helen M. M. Miller, Alan R. R. Mackie, Christine Boesch
Summary: Weaning causes gut microbiota disruption and post-weaning diarrhea. Red beetroot, containing bioactive compounds, has potential to improve gut microbiota dysbiosis and promote gut metabolite production in weaned pigs. In this study, weaned pigs were fed diets supplemented with different levels of red beetroot, and the results showed that 2% red beetroot improved gut microbial richness while 4% led to decreased cecal diversity and reduced short chain fatty acids and secondary bile acid concentrations. Red beetroot has components that can improve gut microbiota and metabolite output of weaned pigs.
Article
Nutrition & Dietetics
Yiwei Sun, Ning Ma, Zengkai Qi, Meng Han, Xi Ma
Summary: This study investigated whether coated ZnO (C_ZnO) in low dose could replace the traditional dose of ZnO to improve the growth performance, intestinal function, and gut microbiota structures in weaned piglets. The results showed that a low concentration of C_ZnO could effectively promote growth performance and reduce diarrhea by improving small intestinal morphology and permeability, enhancing barrier function, and regulating gut microbiota structure.
FRONTIERS IN NUTRITION
(2022)
Article
Agriculture, Dairy & Animal Science
Jiali Chen, Yan Li, Bing Yu, Daiwen Chen, Xiangbing Mao, Ping Zheng, Junqiu Luo, Jun He
JOURNAL OF ANIMAL SCIENCE
(2018)
Article
Biochemistry & Molecular Biology
Jiali Chen, Bing Yu, Daiwen Chen, Zhiqing Huang, Xiangbing Mao, Ping Zheng, Jie Yu, Junqiu Luo, Jun He
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2018)
Article
Agriculture, Dairy & Animal Science
Chenyang Li, Jiali Chen, Man Zhao, Mengqi Liu, Zhengkai Yue, Lei Liu, Fuchang Li
Summary: The study found that adding sodium butyrate to feed can significantly improve slaughter performance, enhance serum indexes, and strengthen intestinal barrier function in rabbits.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Jiali Chen, Yuheng Luo, Yan Li, Daiwen Chen, Bing Yu, Jun He
Summary: Chlorogenic acid (CGA) is a natural polyphenol compound with antioxidant and anti-inflammatory activities. It can attenuate oxidative stress-induced inflammation and injury in the intestinal epithelium by co-regulating the PI3K/Akt and IκBα/NF-κB signaling pathways.
Article
Microbiology
Jiali Chen, Fuchang Li, Weiren Yang, Shuzhen Jiang, Yang Li
Summary: The study demonstrated that dietary supplementation with exogenous catalase (CAT) can improve intestinal development and protect against LPS-induced intestinal mucosa injury in weaned pigs by enhancing intestinal antioxidant capacity and altering microbiota composition.
MICROBIOLOGY SPECTRUM
(2021)
Article
Veterinary Sciences
Jiali Chen, Fuchang Li, Weiren Yang, Shuzhen Jiang, Yang Li
Summary: The study revealed significant differences in microbial abundances and community structures between sows with different litter sizes and gestation stages, which were associated with changes in plasma biochemical parameters, inflammatory factors, and immunoglobulin. Additionally, there was a significant correlation between litter size and gut microbiota of sows, providing a microbial perspective to improve sow reproductive performance in pig production.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Veterinary Sciences
Jiali Chen, Daiwen Chen, Bing Yu, Yuheng Luo, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Zhiqing Huang, Hui Yan, Jun He
Summary: This study found that chlorogenic acid (CGA) can attenuate oxidative stress-induced growth retardation and intestinal mucosa disruption in weaned pigs. It does so by increasing antioxidative capacity, enhancing intestinal barrier integrity, and regulating the expression levels of relevant genes.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Microbiology
Jiali Chen, Zhicheng Song, Rongmei Ji, Yongxu Liu, Hong Zhao, Lei Liu, Fuchang Li
Summary: The study demonstrated that dietary supplementation with 800 mg/kg chlorogenic acid can significantly improve the growth performance of weaned rabbits by enhancing intestinal structural integrity, improving intestinal epithelium function, and modulating gut microbiota composition and diversity.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Jiali Chen, Hongmei Xie, Daiwen Chen, Bing Yu, Xiangbing Mao, Ping Zheng, Jie Yu, Yuheng Luo, Junqiu Luo, Jun He