Microdroplet-based cell culture models and their application

In vitro cancer cell–ECM interactions inform in vivo cancer treatment

(2016) Andrew W. Holle et al.   ADVANCED DRUG DELIVERY REVIEWS

Emulsion technologies for multicellular tumour spheroid radiation assays

(2016) Kay S. McMillan et al.   ANALYST

Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics

(2016) Nachiket Shembekar et al.   LAB ON A CHIP

Generation and functional assessment of 3D multicellular spheroids in droplet based microfluidics platform

(2016) P. Sabhachandani et al.   LAB ON A CHIP

High Throughput Studies of Cell Migration in 3D Microtissues Fabricated by a Droplet Microfluidic Chip

(2016) Xiangchen Che et al.   Micromachines

Droplet microfluidics in (bio)chemical analysis

(2015) Evgenia Yu Basova et al.   ANALYST

Droplet-based microfluidics for making uniform-sized cellular spheroids in alginate beads with the regulation of encapsulated cell number

(2015) Choong Kim   BioChip Journal

Evaluating Biomaterial- and Microfluidic-Based 3D Tumor Models

(2015) Mariana R. Carvalho et al.   TRENDS IN BIOTECHNOLOGY

Mixed hydrogel bead-based tumor spheroid formation and anticancer drug testing

(2014) Yaolei Wang et al.   ANALYST

Microfluidic device for continuous observation of cellular behaviors in specialized core-shell microcapsules

(2014) Choong Kim et al.   BioChip Journal

Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo

(2014) John A. Hickman et al.   Biotechnology Journal

Research highlights: microfluidic single-cell analysis from nucleic acids to proteins to functions

(2014) Rajan P. Kulkarni et al.   LAB ON A CHIP

A droplet-based heterogeneous immunoassay for screening single cells secreting antigen-specific antibodies

(2014) Samin Akbari et al.   LAB ON A CHIP

Identification and genetic analysis of cancer cells with PCR-activated cell sorting

(2014) Dennis J. Eastburn et al.   NUCLEIC ACIDS RESEARCH

Rapid detection of single bacteria in unprocessed blood using Integrated Comprehensive Droplet Digital Detection

(2014) Dong-Ku Kang et al.   Nature Communications

Encapsulation of single cells on a microfluidic device integrating droplet generation with fluorescence-activated droplet sorting

(2013) Liang Wu et al.   BIOMEDICAL MICRODEVICES

Probing cellular heterogeneity in cytokine-secreting immune cells using droplet-based microfluidics

(2013) Venkatachalam Chokkalingam et al.   LAB ON A CHIP

Droplet-based microfluidic system to form and separate multicellular spheroids using magnetic nanoparticles

(2013) Sungjun Yoon et al.   LAB ON A CHIP

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Single-cell analysis and sorting using droplet-based microfluidics

(2013) Linas Mazutis et al.   Nature Protocols

In Vitro Model of Tumor Cell Extravasation

(2013) Jessie S. Jeon et al.   PLoS One

Live single cell functional phenotyping in droplet nano-liter reactors

(2013) Tania Konry et al.   Scientific Reports

Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment

(2013) Hon Fai Chan et al.   Scientific Reports

Monodisperse collagen–gelatin beads as potential platforms for 3D cell culturing

(2013) Shaohua Ma et al.   Journal of Materials Chemistry B

A droplet-based microfluidic device for long-term culture and longitudinal observation of Caenorhabditis elegans

(2012) Dawei Ying et al.   BioChip Journal

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

(2012) Brendon M. Baker et al.   JOURNAL OF CELL SCIENCE

A microfluidic-based device for study of transendothelial invasion of tumor aggregates in realtime

(2012) Qian Zhang et al.   LAB ON A CHIP

Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels

(2012) Yoojin Shin et al.   Nature Protocols

Detecting biomarkers with microdroplet technology

(2012) Valérie Taly et al.   TRENDS IN MOLECULAR MEDICINE

Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments

(2011) Ioannis K. Zervantonakis et al.   Biomicrofluidics

Design properties of hydrogel tissue-engineering scaffolds

(2011) Junmin Zhu et al.   Expert Review of Medical Devices

Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering

(2011) Bong Geun Chung et al.   LAB ON A CHIP

Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells

(2010) Daniela Loessner et al.   BIOMATERIALS

Droplet-based microfluidic system for multicellular tumor spheroid formation and anticancer drug testing

(2010) Linfen Yu et al.   LAB ON A CHIP

Carcinoma-associated fibroblasts promoted tumor spheroid invasion on a microfluidic 3D co-culture device

(2010) Tingjiao Liu et al.   LAB ON A CHIP

Dynamics of microfluidic droplets

(2010) Charles N. Baroud et al.   LAB ON A CHIP

3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells

(2009) Wenjie Wang et al.   BIOMATERIALS

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent advances in three-dimensional multicellular spheroid culture for biomedical research

(2008) Ruei-Zhen Lin et al.   Biotechnology Journal

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

(2008) Jenifer Clausell-Tormos et al.   CHEMISTRY & BIOLOGY

Controlled encapsulation of single-cells into monodisperse picolitre drops

(2008) Jon F. Edd et al.   LAB ON A CHIP

Droplet microfluidics

(2008) Shia-Yen Teh et al.   LAB ON A CHIP