Thermosensitive Hydrogel Based on PEO–PPO–PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno‐Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects

Effective Remodelling of Human Osteoarthritic Cartilage by sox9 Gene Transfer and Overexpression upon Delivery of rAAV Vectors in Polymeric Micelles

(2018) Ana Rey-Rico et al.   MOLECULAR PHARMACEUTICS

Minimally Invasive and Regenerative Therapeutics

(2018) Nureddin Ashammakhi et al.   ADVANCED MATERIALS

Biomaterial-guided delivery of gene vectors for targeted articular cartilage repair

(2018) Magali Cucchiarini et al.   Nature Reviews Rheumatology

rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

(2017) Ana Rey-Rico et al.   International Journal of Nanomedicine

The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage

(2017) Qingen Meng et al.   Journal of the Mechanical Behavior of Biomedical Materials

Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects

(2017) Henning Madry et al.   Stem Cells International

Brief Report: Partial- and Full-Thickness Focal Cartilage Defects Contribute Equally to Development of New Cartilage Damage in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

(2017) Ali Guermazi et al.   Arthritis & Rheumatology

Early loss of subchondral bone following microfracture is counteracted by bone marrow aspirate in a translational model of osteochondral repair

(2017) Liang Gao et al.   Scientific Reports

PEO-PPO-PEO Carriers for rAAV-Mediated Transduction of Human Articular Chondrocytes in Vitro and in a Human Osteochondral Defect Model

(2016) Ana Rey-Rico et al.   ACS Applied Materials & Interfaces

Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells

(2016) Ke Tao et al.   Stem Cell Research & Therapy

A novel algorithm for a precise analysis of subchondral bone alterations

(2016) Liang Gao et al.   Scientific Reports

PEO–PPO–PEO micelles as effective rAAV-mediated gene delivery systems to target human mesenchymal stem cells without altering their differentiation potency

(2015) Ana Rey-Rico et al.   Acta Biomaterialia

Effective genetic modification and differentiation of hMSCs upon controlled release of rAAV vectors using alginate/poloxamer composite systems

(2015) P. Díaz-Rodríguez et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comprehensive analysis of translational osteochondral repair: Focus on the histological assessment

(2015) Patrick Orth et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Advancement of the Subchondral Bone Plate in Translational Models of Osteochondral Repair: Implications for Tissue Engineering Approaches

(2015) Patrick Orth et al.   TISSUE ENGINEERING PART B-REVIEWS

Direct rAAV SOX9 administration for durable articular cartilage repair with delayed terminal differentiation and hypertrophy in vivo

(2012) Magali Cucchiarini et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Experimental scoring systems for macroscopic articular cartilage repair correlate with the MOCART score assessed by a high-field MRI at 9.4 T – comparative evaluation of five macroscopic scoring systems in a large animal cartilage defect model

(2012) L. Goebel et al.   OSTEOARTHRITIS AND CARTILAGE

Temporal and spatial modulation of chondrogenic foci in subchondral microdrill holes by chitosan-glycerol phosphate/blood implants

(2010) A. Chevrier et al.   OSTEOARTHRITIS AND CARTILAGE