Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells
Published 2016 View Full Article
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Title
Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells
Authors
Keywords
Human mesenchymal stem cells, Recombinant adeno-associated virus, Multiple gene transfer, Transforming growth factor beta, SOX9, Chondrogenesis
Journal
Stem Cell Research & Therapy
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-02-01
DOI
10.1186/s13287-016-0280-9
References
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Related references
Note: Only part of the references are listed.- Current Progress in Stem Cell-Based Gene Therapy for Articular Cartilage Repair
- (2015) Janina Frisch et al. Current Stem Cell Research & Therapy
- Determination of the Chondrogenic Differentiation Processes in Human Bone Marrow-Derived Mesenchymal Stem Cells Genetically Modified to Overexpress Transforming Growth Factor-β via Recombinant Adeno-Associated Viral Vectors
- (2014) Janina Frisch et al. HUMAN GENE THERAPY
- Overexpression of Wnt11 promotes chondrogenic differentiation of bone marrow-derived mesenchymal stem cells in synergism with TGF-β
- (2014) Shuang Liu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Sox9 Potentiates BMP2-Induced Chondrogenic Differentiation and Inhibits BMP2-Induced Osteogenic Differentiation
- (2014) Junyi Liao et al. PLoS One
- Co-delivery of SOX9 genes and anti-Cbfa-1 siRNA coated onto PLGA nanoparticles for chondrogenesis of human MSCs
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- Zinc-finger protein 145, acting as an upstream regulator of SOX9, improves the differentiation potential of human mesenchymal stem cells for cartilage regeneration and repair
- (2011) Tong Ming Liu et al. ARTHRITIS AND RHEUMATISM
- Cartilage oligomeric matrix protein enhances matrix assembly during chondrogenesis of human mesenchymal stem cells
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- Release of Bioactive Adeno-Associated Virus from Fibrin Scaffolds: Effects of Fibrin Glue Concentrations
- (2011) Hannah H. Lee et al. TISSUE ENGINEERING PART A
- Autologous Bone Marrow–Derived Mesenchymal Stem Cells Versus Autologous Chondrocyte Implantation
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- The basic science of the subchondral bone
- (2010) Henning Madry et al. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
- The Clinical Use of Human Culture–Expanded Autologous Bone Marrow Mesenchymal Stem Cells Transplanted on Platelet-Rich Fibrin Glue in the Treatment of Articular Cartilage Defects
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- Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined withSox9 viarAAV gene transfer
- (2008) Magali Cucchiarini et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Enhanced In Vitro Chondrogenesis of Primary Mesenchymal Stem Cells by Combined Gene Transfer
- (2008) Andre F. Steinert et al. TISSUE ENGINEERING PART A
- Genetic manipulation of human mesenchymal progenitors to promote chondrogenesis using “bead-in-bead” polysaccharide capsules
- (2007) Jodie C. Babister et al. BIOMATERIALS
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