CRISPR/Cas13a‐Powered Electrochemical Microfluidic Biosensor for Nucleic Acid Amplification‐Free miRNA Diagnostics

CRISPR/Cas Systems towards Next-Generation Biosensing

(2019) Yi Li et al.   TRENDS IN BIOTECHNOLOGY

Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor

(2019) Reza Hajian et al.   Nature Biomedical Engineering

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring

(2019) Can Dincer et al.   ADVANCED MATERIALS

CRISPR/Cas Powered Multiplexed Biosensing

(2019) Richard Bruch et al.   TRENDS IN BIOTECHNOLOGY

Unamplified gene sensing via Cas9 on graphene

(2019) Richard Bruch et al.   Nature Biomedical Engineering

An amplification-free electrochemical detection of exosomal miRNA-21 in serum samples

(2018) Kseniia Boriachek et al.   ANALYST

Highly sensitive and specific electrochemical biosensor for microRNA-21 detection by coupling catalytic hairpin assembly with rolling circle amplification

(2018) Qing Li et al.   ANALYST

Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Triggered Isothermal Amplification for Site-Specific Nucleic Acid Detection

(2018) Mengqi Huang et al.   ANALYTICAL CHEMISTRY

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

Electrochemical Characterization of Nanogap Interdigitated Electrode Arrays for Lab-on-a-Chip Applications

(2018) Volha Matylitskaya et al.   JOURNAL OF THE ELECTROCHEMICAL SOCIETY

Field-deployable viral diagnostics using CRISPR-Cas13

(2018) Cameron Myhrvold et al.   SCIENCE

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Nucleic acid hybridization on an electrically reconfigurable network of gold-coated magnetic nanoparticles enables microRNA detection in blood

(2018) Roya Tavallaie et al.   Nature Nanotechnology

In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus

(2018) Raimunda S. S. Azevedo et al.   Scientific Reports

Building the Class 2 CRISPR-Cas Arsenal

(2017) Kevin M. Lewis et al.   MOLECULAR CELL

RNA targeting with CRISPR–Cas13

(2017) Omar O. Abudayyeh et al.   NATURE

miR miR on the wall, who’s the most malignant medulloblastoma miR of them all?

(2017) Xin Wang et al.   NEURO-ONCOLOGY

Two-tailed RT-qPCR: a novel method for highly accurate miRNA quantification

(2017) Peter Androvic et al.   NUCLEIC ACIDS RESEARCH

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

Multiplexed Point-of-Care Testing – xPOCT

(2017) Can Dincer et al.   TRENDS IN BIOTECHNOLOGY

Clinical on-site monitoring of ß-lactam antibiotics for a personalized antibiotherapy

(2017) R. Bruch et al.   Scientific Reports

Circulating microRNAs as Potential Biomarkers of Infectious Disease

(2017) Carolina N. Correia et al.   Frontiers in Immunology

Biosensing: CRISPR-powered diagnostics

(2017) Xiaolei Zuo et al.   Nature Biomedical Engineering

Designed miniaturization of microfluidic biosensor platforms using the stop-flow technique

(2016) C. Dincer et al.   ANALYST

Enzyme spheres as novel tracing tags coupled with target-induced DNAzyme assembly for ultrasensitive electrochemical microRNA assay

(2016) Yongmei Wu et al.   ANALYTICA CHIMICA ACTA

In Situ Growth of Three-Dimensional Graphene Films for Signal-On Electrochemical Biosensing of Various Analytes

(2016) Dongqing Kong et al.   ANALYTICAL CHEMISTRY

Enzyme catalytic amplification of miRNA-155 detection with graphene quantum dot-based electrochemical biosensor

(2016) Tianxing Hu et al.   BIOSENSORS & BIOELECTRONICS

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components

(2016) Keith Pardee et al.   CELL

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

(2016) Alexandra East-Seletsky et al.   NATURE

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

(2016) Omar O. Abudayyeh et al.   SCIENCE

Highly sensitive dual mode electrochemical platform for microRNA detection

(2016) Pawan Jolly et al.   Scientific Reports

Lift-Off Free Fabrication Approach for Periodic Structures with Tunable Nano Gaps for Interdigitated Electrode Arrays

(2015) Stefan Partel et al.   ACS Nano

Emerging Biosensing Approaches for microRNA Analysis

(2015) Richard M. Graybill et al.   ANALYTICAL CHEMISTRY

Electrochemical sensing of microRNAs: Avenues and paradigms

(2015) Mahmoud Labib et al.   BIOSENSORS & BIOELECTRONICS

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

(2015) Bernd Zetsche et al.   CELL

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

(2015) Sergey Shmakov et al.   MOLECULAR CELL

A review: microRNA detection methods

(2015) Tian Tian et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Target-Responsive, DNA Nanostructure-Based E-DNA Sensor for microRNA Analysis

(2014) Meihua Lin et al.   ANALYTICAL CHEMISTRY

Magnetobiosensors Based on Viral Protein p19 for MicroRNA Determination in Cancer Cells and Tissues

(2014) Susana Campuzano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification and consequences of miRNA–target interactions — beyond repression of gene expression

(2014) Jean Hausser et al.   NATURE REVIEWS GENETICS

miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP

(2014) D Hühn et al.   ONCOGENE

Point-of-care Diagnostic Tools to Detect Circulating MicroRNAS as Biomarkers of Disease

(2014) Luis Vaca   SENSORS

Silencing of the miR-17 92 Cluster Family Inhibits Medulloblastoma Progression

(2013) B. L. Murphy et al.   CANCER RESEARCH

Three-Mode Electrochemical Sensing of Ultralow MicroRNA Levels

(2013) Mahmoud Labib et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrochemical detection of miRNA-222 by use of a magnetic bead-based bioassay

(2012) Francesca Bettazzi et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

An electrochemical sensor based on label-free functional allosteric molecular beacons for detection target DNA/miRNA

(2012) Zhimin Cai et al.   BIOSENSORS & BIOELECTRONICS

Fabrication process development for a high sensitive electrochemical IDA sensor

(2012) S. Partel et al.   MICROELECTRONIC ENGINEERING

MicroRNA profiling: approaches and considerations

(2012) Colin C. Pritchard et al.   NATURE REVIEWS GENETICS

ThemiR-17∼92cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

(2009) Tamar Uziel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA