α-Branched amines by catalytic 1,1-addition of C–H bonds and aminating agents to terminal alkenes

Ir-Catalyzed Intermolecular Branch-Selective Allylic C–H Amidation of Unactivated Terminal Olefins

(2019) Honghui Lei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intermolecular, Branch-Selective and Redox-Neutral Cp*IrIII-Catalyzed Allylic C-H Amidation

(2019) Tobias Knecht et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh(III) and Ir(III)Cp* Complexes Provide Complementary Regioselectivity Profiles in Intermolecular Allylic C–H Amidation Reactions

(2019) Jacob S. Burman et al.   ACS Catalysis

CuH-Catalyzed Asymmetric Hydroamidation of Vinylarenes

(2018) Yujing Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Planar-Chiral Rhodium(III) Catalyst with a Sterically Demanding Cyclopentadienyl Ligand and Its Application in the Enantioselective Synthesis of Dihydroisoquinolones

(2018) Evgeniya A. Trifonova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ni-Catalyzed Carbon–Carbon Bond-Forming Reductive Amination

(2018) Christoph Heinz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic synthesis provides opportunities to transform drug discovery

(2018) David C. Blakemore et al.   Nature Chemistry

Multicomponent synthesis of tertiary alkylamines by photocatalytic olefin-hydroaminoalkylation

(2018) Aaron Trowbridge et al.   NATURE

Transition-Metal-Catalyzed C–H Bond Addition to Carbonyls, Imines, and Related Polarized π Bonds

(2016) Joshua R. Hummel et al.   CHEMICAL REVIEWS

Copper-Catalyzed Enantioselective Addition of Styrene-Derived Nucleophiles to Imines Enabled by Ligand-Controlled Chemoselective Hydrocupration

(2016) Yang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Catalysis Powered by Chiral Cyclopentadienyl Ligands

(2016) Christopher G. Newton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective amine α-functionalization via palladium-catalysed C–H arylation of thioamides

(2016) Pankaj Jain et al.   Nature Chemistry

Native functionality in triple catalytic cross-coupling: sp3 C-H bonds as latent nucleophiles

(2016) M. H. Shaw et al.   SCIENCE

Enantioselective 1,1-Arylborylation of Alkenes: Merging Chiral Anion Phase Transfer with Pd Catalysis

(2015) Hosea M. Nelson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Studies on the Rh(III)-Mediated Amido Transfer Process Leading to Robust C–H Amination with a New Type of Amidating Reagent

(2015) Yoonsu Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-catalysed syn-carboamination of alkenes via a transient directing group

(2015) Tiffany Piou et al.   NATURE

Catalytic asymmetric hydroamination of unactivated internal olefins to aliphatic amines

(2015) Y. Yang et al.   SCIENCE

N-Substituted Hydroxylamines as Synthetically Versatile Amino Sources in the Iridium-Catalyzed Mild C–H Amidation Reaction

(2014) Pitambar Patel et al.   ORGANIC LETTERS

Merging photoredox with nickel catalysis: Coupling of  -carboxyl sp3-carbons with aryl halides

(2014) Z. Zuo et al.   SCIENCE

Metal-Catalyzed Nitrogen-Atom Transfer Methods for the Oxidation of Aliphatic C–H Bonds

(2012) Jennifer L. Roizen et al.   ACCOUNTS OF CHEMICAL RESEARCH

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition-Metal Complexes

(2012) Eric M. Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biotinylated Rh(III) Complexes in Engineered Streptavidin for Accelerated Asymmetric C-H Activation

(2012) T. K. Hyster et al.   SCIENCE

Chiral Cyclopentadienyl Ligands as Stereocontrolling Element in Asymmetric C-H Functionalization

(2012) B. Ye et al.   SCIENCE

Rhodium-Catalyzed Direct Addition of Aryl CH Bonds to N-Sulfonyl Aldimines

(2011) Yang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Arylation of Boc-Imines via C−H Bond Functionalization

(2011) Andy S. Tsai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Palladium-Catalyzed Three-Component Cross-Coupling of Conjugated Dienes or Terminal Alkenes with Vinyl Triflates and Boronic Acids

(2011) Longyan Liao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Heterocycle Synthesis Using an Internal Oxidant: Improved Reactivity and Mechanistic Studies

(2011) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of an  -Amino C-H Arylation Reaction Using the Strategy of Accelerated Serendipity

(2011) A. McNally et al.   SCIENCE

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis and Applications oftert-Butanesulfinamide

(2010) MaryAnn T. Robak et al.   CHEMICAL REVIEWS

Reactivity and Regioselectivity of Insertion of Unsaturated Molecules into M−C (M = Ir, Rh) Bonds of Cyclometalated Complexes

(2010) Ling Li et al.   ORGANOMETALLICS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY