Radiation as an In Situ Auto-Vaccination: Current Perspectives and Challenges
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Title
Radiation as an In Situ Auto-Vaccination: Current Perspectives and Challenges
Authors
Keywords
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Journal
Vaccines
Volume 7, Issue 3, Pages 100
Publisher
MDPI AG
Online
2019-08-26
DOI
10.3390/vaccines7030100
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Note: Only part of the references are listed.- Stereotactic Radiotherapy for Oligometastasis
- (2019) Sotaro Otake et al. Cancers
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- (2018) Jason J. Luke et al. JOURNAL OF CLINICAL ONCOLOGY
- Immune checkpoint therapy in liver cancer
- (2018) Feng Xu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Immunological Mechanisms Responsible for Radiation-Induced Abscopal Effect
- (2018) María E. Rodríguez-Ruiz et al. TRENDS IN IMMUNOLOGY
- cGAS–STING and Cancer: Dichotomous Roles in Tumor Immunity and Development
- (2018) Kevin W. Ng et al. TRENDS IN IMMUNOLOGY
- Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current Challenges and Future Directions
- (2018) Yifan Wang et al. Frontiers in Pharmacology
- Combining immunotherapy and radiotherapy in lung cancer
- (2018) Neeraj Bhalla et al. Journal of Thoracic Disease
- Efficacy of combined hypo-fractionated radiotherapy and anti-PD-1 monotherapy in difficult-to-treat advanced melanoma patients
- (2018) Anissa Roger et al. OncoImmunology
- Immunotherapy and Symptomatic Radiation Necrosis in Patients With Brain Metastases Treated With Stereotactic Radiation
- (2018) Allison M. Martin et al. JAMA Oncology
- Understanding Intratumor Heterogeneity and Evolution in NSCLC and Potential New Therapeutic Approach
- (2018) Taichiro Goto et al. Cancers
- Abscopal effect of radiotherapy combined with immune checkpoint inhibitors
- (2018) Yang Liu et al. Journal of Hematology & Oncology
- Radiation, inflammation and the immune response in cancer
- (2018) Kelly J. McKelvey et al. MAMMALIAN GENOME
- Identifying neoantigens for use in immunotherapy
- (2018) Sharon Hutchison et al. MAMMALIAN GENOME
- The Reciprocity between Radiotherapy and Cancer Immunotherapy
- (2018) Yifan Wang et al. CLINICAL CANCER RESEARCH
- Nobel committee honors tumor immunologists
- (2018) Anand Rotte et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Observation of Nonreciprocal Wave Propagation in a Dynamic Phononic Lattice
- (2018) Yifan Wang et al. PHYSICAL REVIEW LETTERS
- Very early response of circulating tumour–derived DNA in plasma predicts efficacy of nivolumab treatment in patients with non–small cell lung cancer
- (2017) Yuki Iijima et al. EUROPEAN JOURNAL OF CANCER
- Phase 1 Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma Patients With Brain Metastases
- (2017) Noelle L. Williams et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Multicenter Evaluation of the Tolerability of Combined Treatment With PD-1 and CTLA-4 Immune Checkpoint Inhibitors and Palliative Radiation Therapy
- (2017) Andrew Bang et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Previous radiotherapy and the clinical activity and toxicity of pembrolizumab in the treatment of non-small-cell lung cancer: a secondary analysis of the KEYNOTE-001 phase 1 trial
- (2017) Narek Shaverdian et al. LANCET ONCOLOGY
- Concurrent radiotherapy for patients with metastatic melanoma and receiving anti-programmed-death 1 therapy
- (2017) Amélie Aboudaram et al. MELANOMA RESEARCH
- Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer
- (2017) Scott J. Antonia et al. NEW ENGLAND JOURNAL OF MEDICINE
- Exceptional Response to Nivolumab and Stereotactic Body Radiation Therapy (SBRT) in Neuroendocrine Cervical Carcinoma with High Tumor Mutational Burden: Management Considerations from the Center For Personalized Cancer Therapy at UC San Diego Moores Cancer Center
- (2017) Andrew Sharabi et al. ONCOLOGIST
- DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells
- (2017) Hiro Sato et al. Nature Communications
- DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
- (2017) Claire Vanpouille-Box et al. Nature Communications
- DNA Damage and Repair Biomarkers of Immunotherapy Response
- (2017) Kent W. Mouw et al. Cancer Discovery
- Improved time to disease progression in the brain in patients with melanoma brain metastases treated with concurrent delivery of radiosurgery and ipilimumab
- (2017) Tijana Skrepnik et al. OncoImmunology
- TREX1 dictates the immune fate of irradiated cancer cells
- (2017) Claire Vanpouille-Box et al. OncoImmunology
- Melanoma brain metastases treated with stereotactic radiosurgery and concurrent pembrolizumab display marked regression; efficacy and safety of combined treatment
- (2017) Erik S. Anderson et al. Journal for ImmunoTherapy of Cancer
- A meta-analysis of the abscopal effect in preclinical models: Is the biologically effective dose a relevant physical trigger?
- (2017) Raffaella Marconi et al. PLoS One
- Clinical outcomes of melanoma brain metastases treated with stereotactic radiosurgery and anti-PD-1 therapy, anti-CTLA-4 therapy, BRAF/MEK inhibitors, BRAF inhibitor, or conventional chemotherapy
- (2016) K. A. Ahmed et al. ANNALS OF ONCOLOGY
- IL-6 controls resistance to radiation by suppressing oxidative stress via the Nrf2-antioxidant pathway in oral squamous cell carcinoma
- (2016) Yuichiro Matsuoka et al. BRITISH JOURNAL OF CANCER
- Improved survival and complete response rates in patients with advanced melanoma treated with concurrent ipilimumab and radiotherapy versus ipilimumab alone
- (2016) Kristian M. Koller et al. CANCER BIOLOGY & THERAPY
- Abscopal Benefits of Localized Radiotherapy Depend on Activated T-cell Trafficking and Distribution between Metastatic Lesions
- (2016) J. T. Poleszczuk et al. CANCER RESEARCH
- Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells
- (2016) Chad Tang et al. CLINICAL CANCER RESEARCH
- Systematic review of case reports on the abscopal effect
- (2016) Yazan Abuodeh et al. CURRENT PROBLEMS IN CANCER
- Concurrent irradiation with the anti-programmed cell death ligand-1 immune checkpoint blocker durvalumab: Single centre subset analysis from a phase 1/2 trial
- (2016) Antonin Levy et al. EUROPEAN JOURNAL OF CANCER
- Rationale for anti-OX40 cancer immunotherapy
- (2016) Sandrine Aspeslagh et al. EUROPEAN JOURNAL OF CANCER
- Safety and Efficacy of Radiation Therapy in Advanced Melanoma Patients Treated With Ipilimumab
- (2016) Rosie Qin et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- A Prospective Clinical Trial Combining Radiation Therapy With Systemic Immunotherapy in Metastatic Melanoma
- (2016) Susan M. Hiniker et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Activity and safety of radiotherapy with anti-PD-1 drug therapy in patients with metastatic melanoma
- (2016) E. Liniker et al. OncoImmunology
- Can abscopal effects of local radiotherapy be predicted by modeling T cell trafficking?
- (2016) Sandra Demaria et al. Journal for ImmunoTherapy of Cancer
- Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy
- (2015) K. A. Ahmed et al. ANNALS OF ONCOLOGY
- Abscopal effects of radiation therapy: A clinical review for the radiobiologist
- (2015) Shankar Siva et al. CANCER LETTERS
- T cell receptor binding affinity governs the functional profile of cancer-specific CD8+T cells
- (2015) M. P. Tan et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Stereotactic Radiosurgery for Melanoma Brain Metastases in Patients Receiving Ipilimumab: Safety Profile and Efficacy of Combined Treatment
- (2015) Ana P. Kiess et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Landscape of Tumor Antigens in T Cell Immunotherapy
- (2015) S. Ilyas et al. JOURNAL OF IMMUNOLOGY
- Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial
- (2015) Encouse B Golden et al. LANCET ONCOLOGY
- Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
- (2015) Christina Twyman-Saint Victor et al. NATURE
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- (2015) N. A. Rizvi et al. SCIENCE
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- (2014) Patricia A.J. Muller et al. CANCER CELL
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- (2014) A. A. Lugade et al. JOURNAL OF IMMUNOLOGY
- Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial
- (2014) Eugene D Kwon et al. LANCET ONCOLOGY
- Targeted radiotherapy with gold nanoparticles: current status and future perspectives
- (2014) Wilfred Ngwa et al. Nanomedicine
- Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
- (2014) Roy S. Herbst et al. NATURE
- Defining Molecular Signature of Pro-Immunogenic Radiotherapy Targets in Human Prostate Cancer Cells
- (2014) Molykutty J. Aryankalayil et al. RADIATION RESEARCH
- Combining Radiation and Immunotherapy: A New Systemic Therapy for Solid Tumors?
- (2014) C. Tang et al. Cancer Immunology Research
- Survival of melanoma patients with brain metastases treated with ipilimumab and stereotactic radiosurgery
- (2014) Karim Tazi et al. Cancer Medicine
- Functional Relationship between Tumor-Associated Macrophages and Macrophage Colony-Stimulating Factor as Contributors to Cancer Progression
- (2014) Damya Laoui et al. Frontiers in Immunology
- Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study
- (2013) S. F. Slovin et al. ANNALS OF ONCOLOGY
- Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8+ T cells
- (2013) Joanne Y. H. Lim et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer
- (2013) J. Xu et al. CANCER RESEARCH
- Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors
- (2013) Chao-Yi Wu et al. CLINICAL CANCER RESEARCH
- Abscopal effect of radiation therapy: Interplay between radiation dose and p53 status
- (2013) Lidia Strigari et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Radiation and immunotherapy: a synergistic combination
- (2013) Anusha Kalbasi et al. JOURNAL OF CLINICAL INVESTIGATION
- At the Bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy
- (2013) Margaret K. Callahan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift
- (2013) Silvia C. Formenti et al. JNCI-Journal of the National Cancer Institute
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- (2013) Maya Mathew et al. MELANOMA RESEARCH
- Regulation of A1 by OX40 Contributes to CD8+ T Cell Survival and Anti-Tumor Activity
- (2013) Fengyang Lei et al. PLoS One
- Concurrent Radiotherapy and Ipilimumab Immunotherapy for Patients with Melanoma
- (2013) C. A. Barker et al. Cancer Immunology Research
- An Abscopal Response to Radiation and Ipilimumab in a Patient with Metastatic Non-Small Cell Lung Cancer
- (2013) E. B. Golden et al. Cancer Immunology Research
- Ipilimumab and radiation therapy for melanoma brain metastases
- (2013) Ann W. Silk et al. Cancer Medicine
- A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
- (2012) Abhishek D Garg et al. EMBO JOURNAL
- Different affinity windows for virus and cancer-specific T-cell receptors: Implications for therapeutic strategies
- (2012) Milos Aleksic et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors
- (2012) Jing Ni et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Radiotherapy Promotes Tumor-Specific Effector CD8+ T Cells via Dendritic Cell Activation
- (2012) A. Gupta et al. JOURNAL OF IMMUNOLOGY
- C-Met Inhibitor MK-8003 Radiosensitizes c-Met–Expressing Non–Small-Cell Lung Cancer Cells With Radiation-Induced c-Met–Expression
- (2012) Vikas Bhardwaj et al. Journal of Thoracic Oncology
- p53 mutations in cancer
- (2012) Patricia A. J. Muller et al. NATURE CELL BIOLOGY
- Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma
- (2012) Michael A. Postow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway
- (2012) M A Kang et al. Cell Death & Disease
- Role of T lymphocytes in tumor response to radiotherapy
- (2012) Sandra Demaria et al. Frontiers in Oncology
- The Efficacy of Radiotherapy Relies upon Induction of Type I Interferon-Dependent Innate and Adaptive Immunity
- (2011) B. C. Burnette et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The Confluence of Stereotactic Ablative Radiotherapy and Tumor Immunology
- (2011) Steven Eric Finkelstein et al. Clinical & Developmental Immunology
- Cytotoxic T-Lymphocyte-Associated Antigen-4
- (2011) A. K. S. Salama et al. CLINICAL CANCER RESEARCH
- Maximizing Tumor Immunity With Fractionated Radiation
- (2011) Dörthe Schaue et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells
- (2011) Mercedes B. Fuertes et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma
- (2011) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia
- (2011) M. Kalos et al. Science Translational Medicine
- High-Mobility Group Box 1, Oxidative Stress, and Disease
- (2010) Daolin Tang et al. ANTIOXIDANTS & REDOX SIGNALING
- Recruitment of Myeloid but not Endothelial Precursor Cells Facilitates Tumor Regrowth after Local Irradiation
- (2010) S. V. Kozin et al. CANCER RESEARCH
- Radiation Enhances Regulatory T Cell Representation
- (2010) Evelyn L. Kachikwu et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Resistance of CD45RA- T Cells to Apoptosis and Functional Impairment, and Activation of Tumor-Antigen Specific T Cells during Radiation Therapy of Prostate Cancer
- (2010) Z. Tabi et al. JOURNAL OF IMMUNOLOGY
- Ad.Egr-TNF and Local Ionizing Radiation Suppress Metastases by Interferon-β-Dependent Activation of Antigen-specific CD8+ T Cells
- (2010) Yuru Meng et al. MOLECULAR THERAPY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Single dose of anti-CTLA-4 enhances CD8+ T-cell memory formation, function, and maintenance
- (2010) V. A. Pedicord et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TGF-β and immune cells: an important regulatory axis in the tumor microenvironment and progression
- (2010) Li Yang et al. TRENDS IN IMMUNOLOGY
- Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment
- (2009) Y. Lee et al. BLOOD
- Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti-CTLA-4 Antibody
- (2009) M. Z. Dewan et al. CLINICAL CANCER RESEARCH
- Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
- (2009) Theocharis Panaretakis et al. EMBO JOURNAL
- Cutting Edge: OX40 Agonists Can Drive Regulatory T Cell Expansion if the Cytokine Milieu Is Right
- (2009) C. E. Ruby et al. JOURNAL OF IMMUNOLOGY
- Systemic effects of local radiotherapy
- (2009) Silvia C Formenti et al. LANCET ONCOLOGY
- Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
- (2009) Michael R. Elliott et al. NATURE
- Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors
- (2009) François Ghiringhelli et al. NATURE MEDICINE
- PD-1 and Its Ligands in Tolerance and Immunity
- (2008) Mary E. Keir et al. Annual Review of Immunology
- HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion
- (2008) Rose Du et al. CANCER CELL
- Epitope Landscape in Breast and Colorectal Cancer
- (2008) N. H. Segal et al. CANCER RESEARCH
- Anti-OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer
- (2008) Hiroshi Yokouchi et al. CANCER SCIENCE
- NF-κB-MediatedHER2Overexpression inRadiation-Adaptive Resistance
- (2008) Ning Cao et al. RADIATION RESEARCH
- CTLA-4 Control over Foxp3+ Regulatory T Cell Function
- (2008) K. Wing et al. SCIENCE
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