Oridonin Sensitizes Cisplatin-Induced Apoptosis via AMPK/Akt/mTOR-Dependent Autophagosome Accumulation in A549 Cells

Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity

(2019) Uday Kiran Velagapudi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel

(2019) Molly O’Reilly et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of novel oridonin analogues as potent anticancer agents

(2018) Qing-Kun Shen et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Autophagy regulates high concentrations of iodide-induced apoptosis in SH-SY5Y cells

(2018) Bin Zhang et al.   TOXICOLOGY LETTERS

Regulation of selective autophagy: the p62/SQSTM1 paradigm

(2017) Trond Lamark et al.   Essays in Biochemistry

Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer CAR cells: A key role of AMPK and Akt/mTOR signaling

(2017) Chao-Hsiang Chang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

New insights into autophagosome–lysosome fusion

(2017) Shuhei Nakamura et al.   JOURNAL OF CELL SCIENCE

Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms

(2017) Suet Ching Chen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Silencing long non-coding RNA ROR improves sensitivity of non-small-cell lung cancer to cisplatin resistance by inhibiting PI3K/Akt/mTOR signaling pathway

(2017) Hui Shi et al.   TUMOR BIOLOGY

Downregulation of Inhibition of Apoptosis-Stimulating Protein of p53 (iASPP) Suppresses Cisplatin-Resistant Gastric Carcinoma In Vitro

(2017) Jianyong Yu et al.   MEDICAL SCIENCE MONITOR

Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade

(2016) Mingo M. H. Yung et al.   INTEGRATIVE CANCER THERAPIES

Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy

(2016) Alessandra Ferraresi et al.   MOLECULAR CARCINOGENESIS

AMPK activators suppress breast cancer cell growth by inhibiting DVL3-facilitated Wnt/β-catenin signaling pathway activity

(2016) Yu-Feng Zou et al.   Molecular Medicine Reports

Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis

(2016) YUWAN ZHAO et al.   ONCOLOGY REPORTS

Inhibition of autophagy by andrographolide resensitizes cisplatin-resistant non-small cell lung carcinoma cells via activation of the Akt/mTOR pathway

(2016) Shanwei Mi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

MicroRNAs as Regulators of Cisplatin Resistance in Lung Cancer

(2015) Ying Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

The anti-malarial chloroquine suppresses proliferation and overcomes cisplatin resistance of endometrial cancer cells via autophagy inhibition

(2015) Tomohiko Fukuda et al.   GYNECOLOGIC ONCOLOGY

Interleukin polymorphisms associated with overall survival, disease-free survival, and recurrence in non-small cell lung cancer patients

(2015) Nicholas T. Woods et al.   MOLECULAR CARCINOGENESIS

Inhibition of autophagy using 3-methyladenine increases cisplatin-induced apoptosis by increasing endoplasmic reticulum stress in U251 human glioma cells

(2015) RUIJIAN ZHANG et al.   Molecular Medicine Reports

Role of Autophagy in Cisplatin Resistance in Ovarian Cancer Cells

(2014) Juan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lung cancer

(2014) R. D. Neal et al.   BMJ-British Medical Journal

Inhibition of c-Met promoted apoptosis, autophagy and loss of the mitochondrial transmembrane potential in oridonin-induced A549 lung cancer cells

(2013) Ying Liu et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE