Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity

Verdinexor Targeting of CRM1 is a Promising Therapeutic Approach against RSV and Influenza Viruses

(2018) et al.   Viruses-Basel

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V

(2018) Sarah C. Atkinson et al.   Scientific Reports

Investigating nucleo-cytoplasmic shuttling of the human DEAD-box helicase DDX3

(2018) Ruth Brennan et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

(2017) Martijn D. B. van de Garde et al.   Scientific Reports

DDX3 directly regulates TRAF3 ubiquitination and acts as a scaffold to co-ordinate assembly of signalling complexes downstream from MAVS

(2016) Lili Gu et al.   BIOCHEMICAL JOURNAL

Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pH

(2016) Johanna E. Fraser et al.   JOURNAL OF VIROLOGY

DDX3 Interacts with Influenza A Virus NS1 and NP Proteins and Exerts Antiviral Function through Regulation of Stress Granule Formation

(2016) Sathya N. Thulasi Raman et al.   JOURNAL OF VIROLOGY

Antiviral Efficacy of Verdinexor In Vivo in Two Animal Models of Influenza A Virus Infection

(2016) Olivia Perwitasari et al.   PLoS One

Ubiquitin in the activation and attenuation of innate antiviral immunity

(2015) Steven M. Heaton et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parainfluenza Virus 3 Blocks Antiviral Mediators Downstream of the Interferon Lambda Receptor by Modulating Stat1 Phosphorylation

(2015) Kirsten C. Eberle et al.   JOURNAL OF VIROLOGY

RNA helicase DDX3: at the crossroad of viral replication and antiviral immunity

(2015) Fernando Valiente-Echeverría et al.   REVIEWS IN MEDICAL VIROLOGY

The Interaction of RNA Helicase DDX3 with HIV-1 Rev-CRM1-RanGTP Complex during the HIV Replication Cycle

(2015) Seyed Hanif Mahboobi et al.   PLoS One

Formation of a Trimeric Xpo1-Ran[GTP]-Ded1 Exportin Complex Modulates ATPase and Helicase Activities of Ded1

(2015) Glenn Hauk et al.   PLoS One

Nuclear import and export inhibitors alter capsid protein distribution in mammalian cells and reduce Venezuelan Equine Encephalitis Virus replication

(2013) Lindsay Lundberg et al.   ANTIVIRAL RESEARCH

Identification of a Functional Nuclear Localization Signal Mediating Nuclear Import of the Zinc Finger Transcription Factor ZNF24

(2013) Jian-Zhong Li et al.   PLoS One

Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1

(2013) Qingxiang Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions

(2013) Chen Li et al.   VIROLOGY

Development of oligomannose-coated liposome-based nasal vaccine against human parainfluenza virus type 3

(2013) Kyosuke Senchi et al.   Frontiers in Microbiology

An outbreak of human parainfluenza virus 3 infection in an outpatient hematopoietic stem cell transplantation clinic

(2012) Emily R.M. Sydnor et al.   AMERICAN JOURNAL OF INFECTION CONTROL

INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

(2012) Irina Rusinova et al.   NUCLEIC ACIDS RESEARCH

P-body components LSM1, GW182, DDX3, DDX6 and XRN1 are recruited to WNV replication sites and positively regulate viral replication

(2012) Harendra S. Chahar et al.   VIROLOGY

A Physical Interaction Network of Dengue Virus and Human Proteins

(2011) Sudip Khadka et al.   MOLECULAR & CELLULAR PROTEOMICS

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential

(2010) Hiroyuki Oshiumi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I

(2010) M. Solis et al.   JOURNAL OF VIROLOGY

Evolutionary Constraints Acting on DDX3X Protein Potentially Interferes with Rev-Mediated Nuclear Export of HIV-1 RNA

(2010) Deepak Sharma et al.   PLoS One

Characterisation of the passive permeability barrier of nuclear pore complexes

(2009) Dagmar Mohr et al.   EMBO JOURNAL

The Respiratory Syncytial Virus Matrix Protein Possesses a Crm1-Mediated Nuclear Export Mechanism

(2009) R. Ghildyal et al.   JOURNAL OF VIROLOGY

Retinoic acid inducible gene I Activates innate antiviral response against human parainfluenza virus type 3

(2009) Ahmed Sabbah et al.   Virology Journal

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

(2008) Didier Soulat et al.   EMBO JOURNAL

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

The DEAD-Box RNA Helicase DDX3 Associates with Export Messenger Ribonucleoproteins as well asTip-associated Protein and Participates in Translational Control

(2008) Ming-Chih Lai et al.   MOLECULAR BIOLOGY OF THE CELL