Antiviral Efficacy of Verdinexor In Vivo in Two Animal Models of Influenza A Virus Infection

Antiviral strategies against influenza virus: towards new therapeutic approaches

(2014) Arianna Loregian et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Verdinexor, a Novel Selective Inhibitor of Nuclear Export, Reduces Influenza A Virus Replication In Vitro and In Vivo

(2014) O. Perwitasari et al.   JOURNAL OF VIROLOGY

KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia

(2013) Julia Etchin et al.   BRITISH JOURNAL OF HAEMATOLOGY

Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia

(2012) P. Ranganathan et al.   BLOOD

Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma

(2012) Kejie Zhang et al.   EXPERIMENTAL HEMATOLOGY

Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells

(2012) J Etchin et al.   LEUKEMIA

The ferret as a model organism to study influenza A virus infection

(2011) J. A. Belser et al.   Disease Models & Mechanisms

Drugs in Development for Influenza

(2010) David A. Boltz et al.   DRUGS

Triple Combination of Amantadine, Ribavirin, and Oseltamivir Is Highly Active and Synergistic against Drug Resistant Influenza Virus Strains In Vitro

(2010) Jack T. Nguyen et al.   PLoS One

Molecular Determinants for Subcellular Localization of the Severe Acute Respiratory Syndrome Coronavirus Open Reading Frame 3b Protein

(2009) E. C. Freundt et al.   JOURNAL OF VIROLOGY

Structural basis for leucine-rich nuclear export signal recognition by CRM1

(2009) Xiuhua Dong et al.   NATURE

Pandemic Influenza: An Inconvenient Mutation

(2009) S. P. Layne et al.   SCIENCE

Characterization of a CRM1-Dependent Nuclear Export Signal in the C Terminus of Herpes Simplex Virus Type 1 Tegument Protein UL47

(2008) P. Williams et al.   JOURNAL OF VIROLOGY

Severe seasonal influenza in ferrets correlates with reduced interferon and increased IL-6 induction

(2008) Nicholas Svitek et al.   VIROLOGY