Intracerebral Injection of Extracellular Vesicles from Mesenchymal Stem Cells Exerts Reduced Aβ Plaque Burden in Early Stages of a Preclinical Model of Alzheimer’s Disease

Sequential formation of different layers of dystrophic neurites in Alzheimer’s brains

(2019) Md Golam Sharoar et al.   MOLECULAR PSYCHIATRY

Microglia in Alzheimer's disease: A target for immunotherapy

(2019) Shoutang Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Extracellular Vesicles from Mesenchymal Stem Cells Exert Pleiotropic Effects on Amyloid‐β, Inflammation, and Regeneration: A Spark of Hope for Alzheimer's Disease from Tiny Structures?

(2019) Chiara A. Elia et al.   BIOESSAYS

The Pros and Cons of Mesenchymal Stem Cell-Based Therapies

(2019) Aleksandra Musiał-Wysocka et al.   CELL TRANSPLANTATION

2018 Alzheimer's disease facts and figures

(2018)   Alzheimers & Dementia

Microglia-Mediated Neuroprotection, TREM2 , and Alzheimer’s Disease: Evidence From Optical Imaging

(2018) Carlo Condello et al.   BIOLOGICAL PSYCHIATRY

Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities

(2018) Jacques Galipeau et al.   Cell Stem Cell

Alzheimer: A Decade of Drug Design. Why Molecular Topology can be an Extra Edge?

(2018) Riccardo Zanni et al.   Current Neuropharmacology

Exosomes derived from hypoxia-preconditioned mesenchymal stromal cells ameliorate cognitive decline by rescuing synaptic dysfunction and regulating inflammatory responses in APP/PS1 mice

(2018) Guo-Hong Cui et al.   FASEB JOURNAL

Mesenchymal Stem Cell-Derived Extracellular Vesicles Suppresses iNOS Expression and Ameliorates Neural Impairment in Alzheimer’s Disease Mice

(2018) Shan-Shan Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of mesenchymal stem cells transplantation on cognitive deficits in animal models of Alzheimer’s disease: A systematic review and meta-analysis

(2018) Meiling Ge et al.   Brain and Behavior

Multiparametric Analysis of Circulating Exosomes and Other Small Extracellular Vesicles by Advanced Imaging Flow Cytometry

(2018) Sotiris Mastoridis et al.   Frontiers in Immunology

Potential of Extracellular Vesicles in Neurodegenerative Diseases: Diagnostic and Therapeutic Indications

(2018) Mehrnaz Izadpanah et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Anti‑inflammatory effects of bone marrow mesenchymal stem cells on mice with Alzheimer's disease

(2018) Yan Wei et al.   Experimental and Therapeutic Medicine

Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

(2017) Mariana A. de Godoy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Practical considerations for choosing a mouse model of Alzheimer’s disease

(2017) Joanna L. Jankowsky et al.   Molecular Neurodegeneration

Bone Marrow-Derived Mesenchymal Stem Cells-Derived Exosomes Promote Survival of Retinal Ganglion Cells Through miRNA-Dependent Mechanisms

(2017) Ben Mead et al.   Stem Cells Translational Medicine

Randomized trial on the effects of a combined physical/cognitive training in aged MCI subjects: the Train the Brain study

(2017)   Scientific Reports

Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease

(2016) Katherine R. Sadleir et al.   ACTA NEUROPATHOLOGICA

Extracellular Vesicles in Physiology, Pathology, and Therapy of the Immune and Central Nervous System, with Focus on Extracellular Vesicles Derived from Mesenchymal Stem Cells as Therapeutic Tools

(2016) Sylwia Koniusz et al.   Frontiers in Cellular Neuroscience

Identity, proliferation capacity, genomic stability and novel senescence markers of mesenchymal stem cells isolated from low volume of human bone marrow

(2016) Gabrielis Kundrotas et al.   Oncotarget

Amyloid-β 1–24 C-terminal truncated fragment promotes amyloid-β 1–42 aggregate formation in the healthy brain

(2016) Sonia Mazzitelli et al.   Acta Neuropathologica Communications

Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions

(2016) Mariano Di Trapani et al.   Scientific Reports

Safety and biodistribution study of bone marrow–derived mesenchymal stromal cells and mononuclear cells and the impact of the administration route in an intact porcine model

(2015) Tuomas Mäkelä et al.   CYTOTHERAPY

Murine adipose-derived mesenchymal stromal cell vesicles: in vitro clues for neuroprotective and neuroregenerative approaches

(2015) Alessia Farinazzo et al.   CYTOTHERAPY

Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR)

(2015) Xavier Gallart-Palau et al.   Scientific Reports

Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential

(2014) Tatiana Lopatina et al.   Cell Communication and Signaling

Decreased Amyloid-β Pathologies by Intracerebral Loading of Glycosphingolipid-enriched Exosomes in Alzheimer Model Mice

(2014) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inconsistencies and Controversies Surrounding the Amyloid Hypothesis of Alzheimer's Disease

(2014) Gary P Morris et al.   Acta Neuropathologica Communications

Paracrine Mechanisms of Mesenchymal Stem Cell-Based Therapy: Current Status and Perspectives

(2013) Xiaoting Liang et al.   CELL TRANSPLANTATION

Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats

(2013) Hongqi Xin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Evidences for B6C3-Tg (APPswe/PSEN1dE9) Double-Transgenic Mice Between 3 and 10 Months as an Age-Related Alzheimer’s Disease Model

(2013) Zhiyong Zhong et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles

(2013) Hongqi Xin et al.   STEM CELLS

Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes

(2013) Takeshi Katsuda et al.   Scientific Reports

Stain-Free technology as a normalization tool in Western blot analysis

(2012) Anne Gürtler et al.   ANALYTICAL BIOCHEMISTRY

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Preventive and Therapeutic Effects of Intravenous Human Adipose-Derived Stem Cells in Alzheimer’s Disease Mice

(2012) Saeromi Kim et al.   PLoS One

The role of microglia in amyloid clearance from the AD brain

(2010) C. Y. Daniel Lee et al.   JOURNAL OF NEURAL TRANSMISSION

The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease

(2010) Hyun Ju Lee et al.   NEUROSCIENCE LETTERS

Establishing Primary Adult Fibroblast Cultures From Rodents

(2010) Andrei Seluanov et al.   Jove-Journal of Visualized Experiments

The Role of Microglia in Antibody-Mediated Clearance of Amyloid-Beta from the Brain

(2009) Dave Morgan   CNS & Neurological Disorders-Drug Targets

Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury

(2009) S. Bruno et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

 -Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer's Disease

(2009) L. Serneels et al.   SCIENCE

Intracerebral Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells Reduces Amyloid-Beta Deposition and Rescues Memory Deficits in Alzheimer's Disease Mice by Modulation of Immune Responses

(2009) Jong Kil Lee et al.   STEM CELLS

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY