The Cynomolgus Macaque MHC Polymorphism in Experimental Medicine

Adoptive T Cell Therapy Strategies for Viral Infections in Patients Receiving Haematopoietic Stem Cell Transplantation

(2019) Giorgio Ottaviano et al.   Cells

Strategies of adoptive T -cell transfer to treat refractory viral infections post allogeneic stem cell transplantation

(2019) Theresa Kaeuferle et al.   Journal of Hematology & Oncology

Valine 11 and phenylalanine 13 have a greater impact on the T-cell response to citrullinated peptides than the 70–74 shared epitope of the DRB1 molecule in macaques

(2019) Samuel Bitoun et al.   ANNALS OF THE RHEUMATIC DISEASES

Clinical and evolutionary consequences of HIV adaptation to HLA

(2019) Santiago Avila-Rios et al.   Current Opinion in HIV and AIDS

HLA‐E: exploiting pathogen‐host interactions for vaccine development

(2019) H. R. Sharpe et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cynomolgus macaque IL37 polymorphism and control of SIV infection

(2019) Takashi Shiina et al.   Scientific Reports

The Emerging Roles of Human Leukocyte Antigen-F in Immune Modulation and Viral Infection

(2019) Aifen Lin et al.   Frontiers in Immunology

Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer

(2018) Zhen Liu et al.   CELL

Importance of cynomolgus monkeys in development of monoclonal antibody drugs

(2018) Kazuhide Iwasaki et al.   Drug Metabolism and Pharmacokinetics

Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo

(2018) Richard T. O’Neil et al.   Nature Communications

Therapeutic effects of anti-CD154 antibody in cynomolgus monkeys with advanced rheumatoid arthritis

(2018) Eun Wha Choi et al.   Scientific Reports

Whole genome sequencing in the search for genes associated with the control of SIV infection in the Mauritian macaque model

(2018) Marc de Manuel et al.   Scientific Reports

Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells

(2018) Pascale André et al.   CELL

The role of KIR and HLA interactions in pregnancy complications

(2017) Francesco Colucci   IMMUNOGENETICS

Improved full-length killer cell immunoglobulin-like receptor transcript discovery in Mauritian cynomolgus macaques

(2017) Trent M. Prall et al.   IMMUNOGENETICS

Major histocompatibility complex haplotyping and long-amplicon allele discovery in cynomolgus macaques from Chinese breeding facilities

(2017) Julie A. Karl et al.   IMMUNOGENETICS

The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques

(2017) Helen L. Wu et al.   JOURNAL OF IMMUNOLOGY

Mauritian cynomolgus macaques with M3M4 MHC genotype control SIVmac251 infection

(2017) Hongzhao Li et al.   JOURNAL OF MEDICAL PRIMATOLOGY

MHC matching improves engraftment of iPSC-derived neurons in non-human primates

(2017) Asuka Morizane et al.   Nature Communications

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models

(2017) Sunao Sugita et al.   Stem Cell Reports

Both Systemic and Intra-articular Immunization with Citrullinated Peptides Are Needed to Induce Arthritis in the Macaque

(2017) Samuel Bitoun et al.   Frontiers in Immunology

Discrimination of Stem Cell Status after Subjecting Cynomolgus Monkey Pluripotent Stem Cells to Naïve Conversion

(2017) Arata Honda et al.   Scientific Reports

Diversification of bothKIRandNKG2natural killer cell receptor genes in macaques - implications for highly complex MHC-dependent regulation of natural killer cells

(2016) Lutz Walter et al.   IMMUNOLOGY

Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein

(2016) S. Anwar Jagessar et al.   JOURNAL OF IMMUNOLOGY

Comparative Analysis of the Endogenous Peptidomes Displayed by HLA-B*27 and Mamu-B*08: Two MHC Class I Alleles Associated with Elite Control of HIV/SIV Infection

(2016) Miguel Marcilla et al.   JOURNAL OF PROTEOME RESEARCH

Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts

(2016) Yuji Shiba et al.   NATURE

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1

(2016) Wilfredo F Garcia-Beltran et al.   NATURE IMMUNOLOGY

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

(2016) S. G. Hansen et al.   SCIENCE

Identification of MHC Haplotypes Associated with Drug-induced Hypersensitivity Reactions in Cynomolgus Monkeys

(2016) Hong Wu et al.   TOXICOLOGIC PATHOLOGY

Recent Advances in Our Understanding of HLA-G Biology: Lessons from a Wide Spectrum of Human Diseases

(2016) Fabio Morandi et al.   Journal of Immunology Research

Cardiomyocytes Derived from MHC-Homozygous Induced Pluripotent Stem Cells Exhibit Reduced Allogeneic Immunogenicity in MHC-Matched Non-human Primates

(2016) Takuji Kawamura et al.   Stem Cell Reports

Successful Transplantation of Retinal Pigment Epithelial Cells from MHC Homozygote iPSCs in MHC-Matched Models

(2016) Sunao Sugita et al.   Stem Cell Reports

Lack of T Cell Response to iPSC-Derived Retinal Pigment Epithelial Cells from HLA Homozygous Donors

(2016) Sunao Sugita et al.   Stem Cell Reports

Leukocyte Ig-Like Receptors – A Model for MHC Class I Disease Associations

(2016) Laura Emily Hudson et al.   Frontiers in Immunology

Role of HLA Adaptation in HIV Evolution

(2016) Henrik N. Kløverpris et al.   Frontiers in Immunology

Identification of five novel MHC class II alleles in cynomolgus macaques of Vietnamese origin

(2016) W. Wang et al.   HLA

Generation of Cynomolgus Monkey Chimeric Fetuses using Embryonic Stem Cells

(2015) Yongchang Chen et al.   Cell Stem Cell

Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines

(2015) Nadia Caccamo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Whole-Genome Sequencing of Six Mauritian Cynomolgus Macaques (Macaca fascicularis) Reveals a Genome-Wide Pattern of Polymorphisms under Extreme Population Bottleneck

(2015) Naoki Osada et al.   Genome Biology and Evolution

No assembly required: Full-length MHC class I allele discovery by PacBio circular consensus sequencing

(2015) Catherine J. Westbrook et al.   HUMAN IMMUNOLOGY

Discovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencing

(2015) Takashi Shiina et al.   IMMUNOGENETICS

Long-Term Control of Simian Immunodeficiency Virus (SIV) in Cynomolgus Macaques Not Associated with Efficient SIV-Specific CD8+T-Cell Responses

(2015) Timothée Bruel et al.   JOURNAL OF VIROLOGY

Expansion of Simian Immunodeficiency Virus (SIV)-Specific CD8 T Cell Lines from SIV-Naive Mauritian Cynomolgus Macaques for Adoptive Transfer

(2015) Mariel S. Mohns et al.   JOURNAL OF VIROLOGY

Conditional Immune Escape during Chronic Simian Immunodeficiency Virus Infection

(2015) Dane D. Gellerup et al.   JOURNAL OF VIROLOGY

The TB-specific CD4 + T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans

(2015) Bianca R. Mothé et al.   TUBERCULOSIS

A critical analysis of the cynomolgus macaque, Macaca fascicularis, as a model to test HIV-1/SIV vaccine efficacy

(2015) Joseph M. Antony et al.   VACCINE

Human CD8+ T-cells Recognizing Peptides from Mycobacterium tuberculosis (Mtb) Presented by HLA-E Have an Unorthodox Th2-like, Multifunctional, Mtb Inhibitory Phenotype and Represent a Novel Human T-cell Subset

(2015) Krista E. van Meijgaarden et al.   PLoS Pathogens

Lessons from the analysis of nonhuman primates for understanding human aging and neurodegenerative diseases

(2015) Jean-Michel Verdier et al.   Frontiers in Neuroscience

MHC and KIR Polymorphisms in Rhesus Macaque SIV Infection

(2015) Lutz Walter et al.   Frontiers in Immunology

High diversity of MIC genes in non-human primates

(2014) Alice Meyer et al.   IMMUNOGENETICS

Study of MHC class II region polymorphism in the Filipino cynomolgus macaque population

(2014) A. Blancher et al.   IMMUNOGENETICS

Differential recombination dynamics within the MHC of macaque species

(2014) Nanine de Groot et al.   IMMUNOGENETICS

Complete Characterization of Killer Ig-Like Receptor (KIR) Haplotypes in Mauritian Cynomolgus Macaques: Novel Insights into Nonhuman Primate KIR Gene Content and Organization

(2014) B. N. Bimber et al.   JOURNAL OF IMMUNOLOGY

Host-Specific Adaptation of HIV-1 Subtype B in the Japanese Population

(2014) T. Chikata et al.   JOURNAL OF VIROLOGY

Allogeneic Lymphocyte Transfer in MHC-Identical Siblings and MHC-Identical Unrelated Mauritian Cynomolgus Macaques

(2014) Edward T. Mee et al.   PLoS One

Effect of MHC Haplotype on Immune Response upon Experimental SHIVSF162P4cy Infection of Mauritian Cynomolgus Macaques

(2014) Alessandra Borsetti et al.   PLoS One

LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection

(2014) Arman A. Bashirova et al.   PLoS Genetics

Macaque Models of Human Infectious Disease

(2013) M. B. Gardner et al.   ILAR JOURNAL

The Essential Detail: The Genetics and Genomics of the Primate Immune Response

(2013) S. Shen et al.   ILAR JOURNAL

Haplessly Hoping: Macaque Major Histocompatibility Complex Made Easy

(2013) R. W. Wiseman et al.   ILAR JOURNAL

Deleterious impact of feto-maternal MHC compatibility on the success of pregnancy in a macaque model

(2013) Alice Aarnink et al.   IMMUNOGENETICS

Immunogenetics of HIV disease

(2013) Maureen P. Martin et al.   IMMUNOLOGICAL REVIEWS

Adoptive Transfer of Lymphocytes Isolated from Simian Immunodeficiency Virus SIVmac239 nef-Vaccinated Macaques Does Not Affect Acute-Phase Viral Loads but May Reduce Chronic-Phase Viral Loads in Major Histocompatibility Complex-Matched Recipients

(2013) J. M. Greene et al.   JOURNAL OF VIROLOGY

Immune clearance of highly pathogenic SIV infection

(2013) Scott G. Hansen et al.   NATURE

Induction of Encephalitis in Rhesus Monkeys Infused with Lymphocryptovirus-Infected B-Cells Presenting MOG34–56 Peptide

(2013) Krista G. Haanstra et al.   PLoS One

T cell response specificity and magnitude against SIVmac239 are not concordant in major histocompatibility complex-matched animals

(2013) Brian T Cain et al.   Retrovirology

Primate Models in Organ Transplantation

(2013) D. J. Anderson et al.   Cold Spring Harbor Perspectives in Medicine

Direct Comparison of Autologous and Allogeneic Transplantation of iPSC-Derived Neural Cells in the Brain of a Nonhuman Primate

(2013) Asuka Morizane et al.   Stem Cell Reports

Single-Nucleotide Polymorphisms Reveal Patterns of Allele Sharing Across the Species Boundary Between Rhesus (Macaca mulatta) and Cynomolgus (M. fascicularis) Macaques

(2012) JESSICA A. SATKOSKI TRASK et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Comprehensive identification of high-frequency and co-occurring Mafa-B, Mafa-DQB1, and Mafa-DRB alleles in cynomolgus macaques of Vietnamese origin

(2012) Fei Ling et al.   HUMAN IMMUNOLOGY

Study of cynomolgus monkey (Macaca fascicularis) Mhc DRB gene polymorphism in four populations

(2012) Antoine Blancher et al.   IMMUNOGENETICS

Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species

(2012) Natasja G. de Groot et al.   IMMUNOGENETICS

The structural basis of HLA-associated drug hypersensitivity syndromes

(2012) Yuri A. Pompeu et al.   IMMUNOLOGICAL REVIEWS

B-Cell Depletion Abrogates T Cell-Mediated Demyelination in an Antibody-Nondependent Common Marmoset Experimental Autoimmune Encephalomyelitis Model

(2012) S. Anwar Jagessar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Comparative analysis in cynomolgus macaque identifies a novel human MHC locus controlling platelet blood counts independently of BAK1

(2012) A. Aarnink et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Specific CD8+ T Cell Responses Correlate with Control of Simian Immunodeficiency Virus Replication in Mauritian Cynomolgus Macaques

(2012) M. L. Budde et al.   JOURNAL OF VIROLOGY

Epstein-Barr virus Peptide Presented by HLA-E is Predominantly Recognized by CD8bright Cells in multiple Sclerosis Patients

(2012) Pernille B. Jørgensen et al.   PLoS One

Ex Vivo SIV-Specific CD8 T Cell Responses in Heterozygous Animals Are Primarily Directed against Peptides Presented by a Single MHC Haplotype

(2012) Justin M. Greene et al.   PLoS One

Characterization of the major histocompatibility complex class IA alleles in cynomolgus macaques of Vietnamese origin

(2012) G.-Q. Zhang et al.   TISSUE ANTIGENS

Positive selection in the major histocompatibility complex class III region of cynomolgus macaques (Macaca fascicularis) of the Philippines origin

(2012) A. Aarnink et al.   TISSUE ANTIGENS

Identification of 23 novel MHC class I alleles in cynomolgus macaques of Philippine and Philippine/Mauritius origins

(2012) J. Lawrence et al.   TISSUE ANTIGENS

Use of Cumulative Poisson Probability Distribution as an Estimator of the Recombination Rate in an Expanding Population: Example of the Macaca fascicularis Major Histocompatibility Complex

(2012) Antoine Blancher et al.   G3-Genes Genomes Genetics

Differential MHC class I expression in distinct leukocyte subsets

(2011) Justin M Greene et al.   BMC IMMUNOLOGY

Characterisation of MHC haplotypes in a breeding colony of Indonesian cynomolgus macaques reveals a high level of diversity

(2011) Jane L. Mitchell et al.   IMMUNOGENETICS

Characterization of full-length MHC class II sequences in Indonesian and Vietnamese cynomolgus macaques

(2011) Hannah M. Creager et al.   IMMUNOGENETICS

Characterization of MHC class I transcripts of a Malaysian cynomolgus macaque by high-throughput pyrosequencing and EST libraries

(2011) Alice Aarnink et al.   IMMUNOGENETICS

Diversity of MHC class I haplotypes in cynomolgus macaques

(2011) Yusuke Saito et al.   IMMUNOGENETICS

Influence of the MHC genotype on the progression of experimental SIV infection in the Mauritian cynomolgus macaque

(2011) Alice Aarnink et al.   IMMUNOGENETICS

Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations

(2011) Kerry S. Campbell et al.   IMMUNOLOGY

Maternal KIR and fetal HLA-C: a fine balance

(2011) Olympe Chazara et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vitrification and transfer of cynomolgus monkey (Macaca fascicularis) embryos fertilized by intracytoplasmic sperm injection

(2011) J. Yamasaki et al.   THERIOGENOLOGY

EAE: imperfect but useful models of multiple sclerosis

(2011) Bert A. ’t Hart et al.   TRENDS IN MOLECULAR MEDICINE

Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells

(2010) D Eastwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

Characterization of the major histocompatibility complex class II DOB, DPB1, and DQB1 alleles in cynomolgus macaques of Vietnamese origin

(2010) Fei Ling et al.   IMMUNOGENETICS

Impact of MHC class II polymorphism on blood counts of CD4+ T lymphocytes in macaque

(2010) Alice Aarnink et al.   IMMUNOGENETICS

Study of cynomolgus monkey (Macaca fascicularis) DRA polymorphism in four populations

(2010) Alice Aarnink et al.   IMMUNOGENETICS

Characterization of Mauritian cynomolgus macaque major histocompatibility complex class I haplotypes by high-resolution pyrosequencing

(2010) Melisa L. Budde et al.   IMMUNOGENETICS

Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta

(2010) NAOKI OSADA et al.   MOLECULAR ECOLOGY

MHC Heterozygote Advantage in Simian Immunodeficiency Virus-Infected Mauritian Cynomolgus Macaques

(2010) S. L. O'Connor et al.   Science Translational Medicine

The Histocompatibility Complex of Rhesus Monkeys. II. A Major Locus Controlling Reactivity in Mixed Lymphocyte Cultures

(2010) H. Balner et al.   TISSUE ANTIGENS

The Histocompatibility Complex of Rhesus Monkeys. I. Serology and Genetics of the RhL-A System

(2010) H. Balner et al.   TISSUE ANTIGENS

Mhc haplotype M3 is associated with early control of SHIVsbg infection in Mauritian cynomolgus macaques

(2010) E. T. Mee et al.   TISSUE ANTIGENS

Mycobacterium tuberculosis Peptides Presented by HLA-E Molecules Are Targets for Human CD8+ T-Cells with Cytotoxic as well as Regulatory Activity

(2010) Simone A. Joosten et al.   PLoS Pathogens

Characterization of cynomolgus and vervet monkey placental MHC class I expression: diversity of the nonhuman primate AG locus

(2009) Gennadiy I. Bondarenko et al.   IMMUNOGENETICS

MHC class I A loci polymorphism and diversity in three Southeast Asian populations of cynomolgus macaque

(2009) Yuki F. Kita et al.   IMMUNOGENETICS

Definition of Mafa-A and -B haplotypes in pedigreed cynomolgus macaques (Macaca fascicularis)

(2009) Nel Otting et al.   IMMUNOGENETICS

Mhc haplotype H6 is associated with sustained control of SIVmac251 infection in Mauritian cynomolgus macaques

(2009) Edward T. Mee et al.   IMMUNOGENETICS

Two MHC Class I Molecules Associated with Elite Control of Immunodeficiency Virus Replication, Mamu-B*08 and HLA-B*2705, Bind Peptides with Sequence Similarity

(2009) J. T. Loffredo et al.   JOURNAL OF IMMUNOLOGY

The HLA‐ER/HLA‐ERGenotype Affects the Natural Course of Hepatitis C Virus (HCV) Infection and Is Associated with HLA‐E–Restricted Recognition of an HCV‐Derived Peptide by Interferon‐γ–Secreting Human CD8+T Cells

(2009) Daniela Schulte et al.   JOURNAL OF INFECTIOUS DISEASES

Mauritian Cynomolgus Macaques Share Two Exceptionally Common Major Histocompatibility Complex Class I Alleles That Restrict Simian Immunodeficiency Virus-Specific CD8+ T Cells

(2009) B. J. Burwitz et al.   JOURNAL OF VIROLOGY

Infection with "Escaped" Virus Variants Impairs Control of Simian Immunodeficiency Virus SIVmac239 Replication in Mamu-B*08-Positive Macaques

(2009) L. E. Valentine et al.   JOURNAL OF VIROLOGY

Adaptation of HIV-1 to human leukocyte antigen class I

(2009) Yuka Kawashima et al.   NATURE

Major histocompatibility complex genotyping with massively parallel pyrosequencing

(2009) Roger W Wiseman et al.   NATURE MEDICINE

Analytical approaches to detect maternal/fetal genotype incompatibilities that increase risk of pre-eclampsia

(2008) Neeta Parimi et al.   BMC Medical Genetics

Characterization of 47 MHC class I sequences in Filipino cynomolgus macaques

(2008) Kevin J. Campbell et al.   IMMUNOGENETICS

MHC class I characterization of Indonesian cynomolgus macaques

(2008) Chad J. Pendley et al.   IMMUNOGENETICS

Assessing Natural Introgression in 2 Biomedical Model Species, the Rhesus Macaque (Macaca mulatta) and the Long-Tailed Macaque (Macaca fascicularis)

(2008) M. Bonhomme et al.   JOURNAL OF HEREDITY

MHC haplotype frequencies in a UK breeding colony of Mauritian cynomolgus macaques mirror those found in a distinct population from the same geographic origin

(2008) Edward T. Mee et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Origin and number of founders in an introduced insular primate: estimation from nuclear genetic data

(2008) M. BONHOMME et al.   MOLECULAR ECOLOGY

Allogeneic Lymphocytes Persist and Traffic in Feral MHC-Matched Mauritian Cynomolgus Macaques

(2008) Justin M. Greene et al.   PLoS One

Comparative study of Tat vaccine regimens in Mauritian cynomolgus and Indian rhesus macaques: Influence of Mauritian MHC haplotypes on susceptibility/resistance to SHIV89.6P infection

(2008) Ruth H. Florese et al.   VACCINE