Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche

Murine hematopoietic stem cell reconstitution potential is maintained by osteopontin during aging

(2018) Jin Li et al.   Scientific Reports

Niche Extracellular Matrix Components and Their Influence on HSC

(2017) Mélanie J. Domingues et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function

(2017) Javed K. Manesia et al.   STEM CELLS AND DEVELOPMENT

Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells

(2017) Soo Im Choi et al.   Oncotarget

Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist

(2016) Benjamin Cao et al.   Nature Communications

The role of CD44 in fetal and adult hematopoietic stem cell regulation

(2015) H. Cao et al.   HAEMATOLOGICA

Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin

(2015) Tommy Hui et al.   MATRIX BIOLOGY

Brief Report: Factors Released by Megakaryocytes Thrombin Cleave Osteopontin to Negatively Regulate Hematopoietic Stem Cells

(2015) Melonie J. Storan et al.   STEM CELLS

The role of CD44 in fetal and adult hematopoietic stem cell regulation

(2015) H. Cao et al.   HAEMATOLOGICA

The Impairment of Osteogenesis in Bone Sialoprotein (BSP) Knockout Calvaria Cell Cultures Is Cell Density Dependent

(2015) Guenaelle Bouet et al.   PLoS One

Development of the Fetal Bone Marrow Niche and Regulation of HSC Quiescence and Homing Ability by Emerging Osteolineage Cells

(2014) Süleyman Coşkun et al.   Cell Reports

The glycosylation profile of osteoadherin alters during endochondral bone formation

(2013) Rachael V. Sugars et al.   BONE

Understanding the role of the microenvironment during definitive hemopoietic development

(2013) Huimin Cao et al.   EXPERIMENTAL HEMATOLOGY

Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vivo probe for bone marrow haemopoietic stem cells

(2013) Benjamin Cao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cell cycle regulation in hematopoietic stem cells

(2011) Eric M. Pietras et al.   JOURNAL OF CELL BIOLOGY

Osteopontin Enhances the Expression and Activity of MMP-2 via the SDF-1/CXCR4 Axis in Hepatocellular Carcinoma Cell Lines

(2011) Rihua Zhang et al.   PLoS One

Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential

(2010) J. Grassinger et al.   BLOOD

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

Human osteoclasts, not osteoblasts, deposit osteopontin onto resorption surfaces: An in vitro and ex vivo study of remodeling bone

(2010) Robert A. Dodds et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Ultrastructural immunolocalization of noncollagenous (osteopontin and osteocalcin) and plasma (albumin and α2HS-glycoprotein) proteins in rat bone

(2010) Marc D. McKee et al.   JOURNAL OF BONE AND MINERAL RESEARCH

BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells

(2009) P. Ramirez et al.   BLOOD

Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with  9 1 and  4 1 integrins

(2009) J. Grassinger et al.   BLOOD

Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells

(2009) R. Behera et al.   CARCINOGENESIS

Linking integrin conformation to function

(2009) J. A. Askari et al.   JOURNAL OF CELL SCIENCE

Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells

(2009) J Dai et al.   ONCOGENE

Osteopontin Promotes Vascular Endothelial Growth Factor Dependent Breast Tumor Growth and Angiogenesis via Autocrine and Paracrine Mechanisms

(2008) G. Chakraborty et al.   CANCER RESEARCH