Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vivo probe for bone marrow haemopoietic stem cells

Granulocyte colony stimulating factor expands hematopoietic stem cells within the central but not endosteal bone marrow region

(2012) Jochen Grassinger et al.   CYTOKINE

Importance of interaction between nerve growth factor and  9 1 integrin in glial tumor angiogenesis

(2012) E. M. Walsh et al.   NEURO-ONCOLOGY

Chemical approaches to synthetic polymer surface biofunctionalization for targeted cell adhesion using small binding motifs

(2012) Guillaume Delaittre et al.   Soft Matter

Integrin Targeted Therapeutics

(2012) Melissa Millard et al.   Theranostics

Reprogramming Urokinase into an Antibody-Recruiting Anticancer Agent

(2011) Charles E. Jakobsche et al.   ACS Chemical Biology

Studies on the Synthesis of cis-4-Hydroxy-L-proline

(2011) Jessica A. Smith et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Fabrication and Selective Functionalization of Amine-Reactive Polymer Multilayers on Topographically Patterned Microwell Cell Culture Arrays

(2011) Adam H. Broderick et al.   BIOMACROMOLECULES

Modeling the molecular basis for α4β1 integrin antagonism

(2011) Oliver E. Hutt et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Spacer length effects on in vitro imaging and surface accessibility of fluorescent inhibitors of prostate specific membrane antigen

(2011) Tiancheng Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential

(2010) J. Grassinger et al.   BLOOD

Integrins as therapeutic targets: lessons and opportunities

(2010) Dermot Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Heterocycle-substituted proline dipeptides as potent VLA-4 antagonists

(2009) Thomas S. Reger et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells

(2009) P. Ramirez et al.   BLOOD

Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with  9 1 and  4 1 integrins

(2009) J. Grassinger et al.   BLOOD

The integrin  9 1 on hematopoietic stem and progenitor cells: involvement in cell adhesion, proliferation and differentiation

(2009) T. D. Schreiber et al.   HAEMATOLOGICA

Discovery ofN-{N-[(3-Cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(l)-prolyl}-4-[(3′,5′-dichloroisonicotinoyl)amino]-(l)-phenylalanine (MK-0668), an Extremely Potent and Orally Active Antagonist of Very Late Antigen-4

(2009) Linus S. Lin et al.   JOURNAL OF MEDICINAL CHEMISTRY

Small-molecule inhibitors of integrin α2β1 that prevent pathological thrombus formation via an allosteric mechanism

(2009) Meredith W. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two-color labeling of temporally defined protein populations in mammalian cells

(2008) Kimberly E. Beatty et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Loss of Integrin α9β1 Results in Defects in Proliferation, Causing Poor Re-Epithelialization during Cutaneous Wound Healing

(2008) Purva Singh et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY