Glycan-Modified Melanoma-Derived Apoptotic Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination

Tumor-Derived Apoptotic Vesicles: With Death They Do Part

(2018) Morad-Remy Muhsin-Sharafaldine et al.   Frontiers in Immunology

Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I

(2018) Sophie K. Horrevorts et al.   Frontiers in Immunology

Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris

(2018) Sarah Caruso et al.   Frontiers in Immunology

Therapeutic Prospects of Extracellular Vesicles in Cancer Treatment

(2018) Daria S. Chulpanova et al.   Frontiers in Immunology

Targeting C-type lectin receptors: a high-carbohydrate diet for dendritic cells to improve cancer vaccines

(2017) Dieke van Dinther et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

(2017) Ugur Sahin et al.   NATURE

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

Disassembly of the Dying: Mechanisms and Functions

(2017) Georgia K. Atkin-Smith et al.   TRENDS IN CELL BIOLOGY

Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

(2017) Abhishek D. Garg et al.   OncoImmunology

Neoantigen landscape dynamics during human melanoma–T cell interactions

(2016) Els M. E. Verdegaal et al.   NATURE

Procoagulant and immunogenic properties of melanoma exosomes, microvesicles and apoptotic vesicles

(2016) Morad-Rémy Muhsin-Sharafaldine et al.   Oncotarget

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

(2016) Marios Giannakis et al.   Cell Reports

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Cross-presentation through langerin and DC-SIGN targeting requires different formulations of glycan-modified antigens

(2015) Cynthia M. Fehres et al.   JOURNAL OF CONTROLLED RELEASE

In situ Delivery of Antigen to DC-SIGN + CD14 + Dermal Dendritic Cells Results in Enhanced CD8 + T-Cell Responses

(2015) Cynthia M. Fehres et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

(2015) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apoptotic blebs from leukemic cells as a preferred source of tumor-associated antigen for dendritic cell-based vaccines

(2014) Jurjen M. Ruben et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Survival, Durable Tumor Remission, and Long-Term Safety in Patients With Advanced Melanoma Receiving Nivolumab

(2014) Suzanne L. Topalian et al.   JOURNAL OF CLINICAL ONCOLOGY

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression

(2014) Wendy WJ Unger et al.   OncoImmunology

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Nivolumab plus Ipilimumab in Advanced Melanoma

(2013) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Skin-Resident Antigen-Presenting Cells: Instruction Manual for Vaccine Development

(2013) Cynthia M. Fehres et al.   Frontiers in Immunology

Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines

(2013) Juan J. García-Vallejo et al.   OncoImmunology

Exploiting the Mutanome for Tumor Vaccination

(2012) J. C. Castle et al.   CANCER RESEARCH

Apoptotic-cell-derived membrane vesicles induce an alternative maturation of human dendritic cells which is disturbed in SLE

(2012) Eva-Marie Fehr et al.   JOURNAL OF AUTOIMMUNITY

Apoptotic cells enhance IL-10 and reduce IL-23 production in human dendritic cells treated with zymosan

(2011) Cristina Municio et al.   MOLECULAR IMMUNOLOGY

Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1 

(2011) Y. Berda-Haddad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Transduction of Dendritic Cells in Human Lymph Nodes and Superior Induction of High-avidity Melanoma-reactive Cytotoxic T Cells by a CD40-targeted Adenovirus

(2010) Basav N. Hangalapura et al.   JOURNAL OF IMMUNOTHERAPY

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17

(2009) Justin H. Fransen et al.   ARTHRITIS AND RHEUMATISM

Protein-glycan interactions in the control of innate and adaptive immune responses

(2008) Yvette van Kooyk et al.   NATURE IMMUNOLOGY