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Title
Cancer Metabolism and the Evasion of Apoptotic Cell Death
Authors
Keywords
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Journal
Cancers
Volume 11, Issue 8, Pages 1144
Publisher
MDPI AG
Online
2019-08-09
DOI
10.3390/cancers11081144
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Note: Only part of the references are listed.- Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
- (2019) Kevin H. Lin et al. Cell Metabolism
- Targeting mitochondrial structure sensitizes acute myeloid leukemia to Venetoclax treatment
- (2019) Xufeng Chen et al. Cancer Discovery
- Developing TRAIL/TRAIL death receptor-based cancer therapies
- (2018) Xun Yuan et al. CANCER AND METASTASIS REVIEWS
- Therapeutic synergy between tigecycline and venetoclax in a preclinical model of MYC / BCL2 double-hit B cell lymphoma
- (2018) Micol Ravà et al. Science Translational Medicine
- Statins enhance efficacy of venetoclax in blood cancers
- (2018) J. Scott Lee et al. Science Translational Medicine
- Effects of statins on the chemoresistance—The antagonistic drug-drug interactions versus the anti-cancer effects
- (2018) Yasin Ahmadi et al. BIOMEDICINE & PHARMACOTHERAPY
- Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells
- (2018) Courtney L. Jones et al. CANCER CELL
- Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in haematological malignancies
- (2018) Aoula Al-Zebeeby et al. HAEMATOLOGICA
- Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia
- (2018) Daniel A. Pollyea et al. NATURE MEDICINE
- MCL-1 inhibition in cancer treatment
- (2018) Weiguo Xiang et al. OncoTargets and Therapy
- High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells
- (2017) L Poulain et al. LEUKEMIA
- Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors
- (2017) Raffaella Iurlaro et al. MOLECULAR AND CELLULAR BIOLOGY
- Expression of glucose transporter 1 and prognosis in non-small cell lung cancer: a pooled analysis of 1665 patients
- (2017) Zhibo Tan et al. Oncotarget
- The prognostic value of GLUT1 in cancers: a systematic review and meta-analysis
- (2017) Min Yu et al. Oncotarget
- Autophagy is a regulator of TRAIL-induced apoptosis in NSCLC A549 cells
- (2017) Yuqing Chen et al. Journal of Cell Communication and Signaling
- mTORC1-Dependent Metabolic Reprogramming Underlies Escape from Glycolysis Addiction in Cancer Cells
- (2016) Raju V. Pusapati et al. CANCER CELL
- Ferroptosis: process and function
- (2016) Y Xie et al. CELL DEATH AND DIFFERENTIATION
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Role of Apoptosis in disease
- (2016) B. Favaloro et al. Aging-US
- Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition
- (2015) N. Jacque et al. BLOOD
- Drug-Induced Death Signaling Strategy Rapidly Predicts Cancer Response to Chemotherapy
- (2015) Joan Montero et al. CELL
- ATF4 mediates necrosis induced by glucose deprivation and apoptosis induced by 2-deoxyglucose in the same cells
- (2015) Clara Lucía León-Annicchiarico et al. FEBS Journal
- ERK2 Mediates Metabolic Stress Response to Regulate Cell Fate
- (2015) Sejeong Shin et al. MOLECULAR CELL
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Targeting mitochondria metabolism for cancer therapy
- (2015) Samuel E Weinberg et al. Nature Chemical Biology
- Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia
- (2015) Steven M Chan et al. NATURE MEDICINE
- Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax
- (2015) R Bajpai et al. ONCOGENE
- Antagonizing Bcl-2 Family Members Sensitizes Neuroblastoma and Ewing’s Sarcoma to an Inhibitor of Glutamine Metabolism
- (2015) Rachelle R. Olsen et al. PLoS One
- Capturing the metabolomic diversity of KRAS mutants in non-small-cell lung cancer cells
- (2015) Laura Brunelli et al. Oncotarget
- The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
- (2014) Anna Stincone et al. BIOLOGICAL REVIEWS
- A critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance
- (2014) Z. Liu et al. BLOOD
- Serine and glycine metabolism in cancer
- (2014) Ivano Amelio et al. TRENDS IN BIOCHEMICAL SCIENCES
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- Regulation of the pentose phosphate pathway in cancer
- (2014) Peng Jiang et al. Protein & Cell
- Bcl-xL in neuroprotection and plasticity
- (2014) Elizabeth A. Jonas et al. Frontiers in Physiology
- Anoikis molecular pathways and its role in cancer progression
- (2013) Paolo Paoli et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure
- (2013) R. L. Thomas et al. GENES & DEVELOPMENT
- The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma
- (2013) C Touzeau et al. LEUKEMIA
- BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response
- (2013) Kristopher A. Sarosiek et al. MOLECULAR CELL
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis
- (2013) T He et al. ONCOGENE
- Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia
- (2013) R. Pan et al. Cancer Discovery
- Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
- (2013) Jason Karch et al. eLife
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Glucose—a sweet way to die
- (2012) Marion MacFarlane et al. CELL CYCLE
- The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type
- (2012) Mariia O. Yuneva et al. Cell Metabolism
- Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
- (2012) Rhonda M. Perciavalle et al. NATURE CELL BIOLOGY
- Bax regulates primary necrosis through mitochondrial dynamics
- (2012) R. S. Whelan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
- (2012) W. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A combination of 2-deoxy-d-glucose and 6-aminonicotinamide induces cell cycle arrest and apoptosis selectively in irradiated human malignant cells
- (2012) Richa Bhardwaj et al. TUMOR BIOLOGY
- Energy metabolism of cancer: Glycolysis versus oxidative phosphorylation (Review)
- (2012) JIE ZHENG Oncology Letters
- Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1
- (2011) Felix M. Wensveen et al. APOPTOSIS
- Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells
- (2011) A. A. Morales et al. BLOOD
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- (2011) S. M. Schoenwaelder et al. BLOOD
- 2-Deoxyglucose Induces Noxa-Dependent Apoptosis in Alveolar Rhabdomyosarcoma
- (2011) S. Ramirez-Peinado et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Cell death by autophagy: facts and apparent artefacts
- (2011) D Denton et al. CELL DEATH AND DIFFERENTIATION
- Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth
- (2011) D. Gaglio et al. Molecular Systems Biology
- Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase
- (2011) Kambiz N. Alavian et al. NATURE CELL BIOLOGY
- 2-Deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines
- (2011) O Zagorodna et al. ONCOGENE
- Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy
- (2011) T. N. Chonghaile et al. SCIENCE
- Cancer cell killing via ROS: To increase or decrease, that is the question
- (2010) Jie Wang et al. CANCER BIOLOGY & THERAPY
- MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner
- (2010) Marc Germain et al. EMBO JOURNAL
- Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells
- (2010) Jonathan L. Coloff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony
- (2010) Kathryn G. Foster et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Proapoptotic Function of Noxa in Human Leukemia Cells Is Regulated by the Kinase Cdk5 and by Glucose
- (2010) Xazmin H. Lowman et al. MOLECULAR CELL
- The BCL-2 Family Reunion
- (2010) Jerry E. Chipuk et al. MOLECULAR CELL
- Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines
- (2010) H Zhang et al. ONCOGENE
- Dysregulation of the mevalonate pathway promotes transformation
- (2010) J. W. Clendening et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
- (2010) F. Weinberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Involvement of cytochrome c oxidase subunits Va and Vb in the regulation of cancer cell metabolism by Bcl-2
- (2009) Z X Chen et al. CELL DEATH AND DIFFERENTIATION
- Cyclophilin D Interacts with Bcl2 and Exerts an Anti-apoptotic Effect
- (2009) Roman A. Eliseev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bcl-xLincreases mitochondrial fission, fusion, and biomass in neurons
- (2009) Sarah B. Berman et al. JOURNAL OF CELL BIOLOGY
- Kinetics of transport and phosphorylation of glucose in cancer cells
- (2009) Sara Rodríguez-Enríquez et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
- (2009) Ismael Samudio et al. JOURNAL OF CLINICAL INVESTIGATION
- Expression levels of p18INK4C modify the cellular efficacy of cyclin-dependent kinase inhibitors via regulation of Mcl-1 expression in tumor cell lines
- (2009) T. Eguchi et al. MOLECULAR CANCER THERAPEUTICS
- Emerging Role for Members of the Bcl-2 Family in Mitochondrial Morphogenesis
- (2009) Arnaud Autret et al. MOLECULAR CELL
- Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
- (2009) Zachary T. Schafer et al. NATURE
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
- (2009) Ping Gao et al. NATURE
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Mimicking the BH3 domain to kill cancer cells
- (2009) T Ni Chonghaile et al. ONCOGENE
- Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation
- (2009) L A Pradelli et al. ONCOGENE
- Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells
- (2009) J. Yun et al. SCIENCE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Regulation of Bcl-2 Family Proteins by Posttranslational Modifications
- (2008) Anthony Letai et al. CURRENT MOLECULAR MEDICINE
- Glucose Metabolism Attenuates p53 and Puma-dependent Cell Death upon Growth Factor Deprivation
- (2008) Yuxing Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Involvement of Protective Autophagy in TRAIL Resistance of Apoptosis-defective Tumor Cells
- (2008) Jie Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dual role of proapoptotic BAD in insulin secretion and beta cell survival
- (2008) Nika N Danial et al. NATURE MEDICINE
- Bcl-2 family proteins and cancer
- (2008) K W Yip et al. ONCOGENE
- Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
- (2008) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTORC1 promotes survival through translational control of Mcl-1
- (2008) J. R. Mills et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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