The making of a Barr body: the mosaic of factors that eXIST on the mammalian inactive X chromosome

Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation

(2015) Fan Yang et al.   GENOME BIOLOGY

ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets

(2014) Kavitha Sarma et al.   CELL

A Dual Role for the Histone Methyltransferase PR-SET7/SETD8 and Histone H4 Lysine 20 Monomethylation in the Local Regulation of RNA Polymerase II Pausing

(2014) Priya Kapoor-Vazirani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mice without MacroH2A Histone Variants

(2014) J. R. Pehrson et al.   MOLECULAR AND CELLULAR BIOLOGY

Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome

(2014) Simão Teixeira da Rocha et al.   MOLECULAR CELL

N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity

(2014) Gohei Nishibuchi et al.   NUCLEIC ACIDS RESEARCH

Dynamics of the Two Heterochromatin Types during Imprinted X Chromosome Inactivation in Vole Microtus levis

(2014) Evgeniya A. Vaskova et al.   PLoS One

Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy

(2014) Andrea Cerase et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and pharmacological reactivation of the mammalian inactive X chromosome

(2014) S. Bhatnagar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PRC1 complex diversity: where is it taking us?

(2014) Jesús Gil et al.   TRENDS IN CELL BIOLOGY

The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation

(2014) Alissa Minkovsky et al.   Epigenetics & Chromatin

Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

(2014) Daniel Smeets et al.   Epigenetics & Chromatin

A prominent and conserved role for YY1 in Xist transcriptional activation

(2014) Mélanie Makhlouf et al.   Nature Communications

Lamin B receptor

(2014) Ada L. Olins et al.   Nucleus

X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease

(2013) Jeannie T. Lee et al.   CELL

Jpx RNA Activates Xist by Evicting CTCF

(2013) Sha Sun et al.   CELL

A “Complex” Issue: Deciphering the Role of Variant PRC1 in ESCs

(2013) Siobhán A. Turner et al.   Cell Stem Cell

Short-Form CDYLb but not long-form CDYLa functions cooperatively with histone methyltransferase G9a in hepatocellular carcinomas

(2013) Hui Wu et al.   GENES CHROMOSOMES & CANCER

Cdyl, a New Partner of the Inactive X Chromosome and Potential Reader of H3K27me3 and H3K9me2

(2013) M. Escamilla-Del-Arenal et al.   MOLECULAR AND CELLULAR BIOLOGY

High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation

(2013) Matthew D. Simon et al.   NATURE

Translating dosage compensation to trisomy 21

(2013) Jun Jiang et al.   NATURE

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway

(2013) Ryu-Suke Nozawa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment

(2013) Arindam Basu et al.   NUCLEIC ACIDS RESEARCH

The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

(2013) J. M. Engreitz et al.   SCIENCE

XIST-induced silencing of flanking genes is achieved by additive action of repeat a monomers in human somatic cells

(2013) Jakub Minks et al.   Epigenetics & Chromatin

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3

(2012) Lígia Tavares et al.   CELL

MicroRNA Regulation of Cbx7 Mediates a Switch of Polycomb Orthologs during ESC Differentiation

(2012) Ana O'Loghlen et al.   Cell Stem Cell

Satb1 and Satb2 Are Dispensable for X Chromosome Inactivation in Mice

(2012) Robert Nechanitzky et al.   DEVELOPMENTAL CELL

Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome

(2012) Anne-Valerie Gendrel et al.   DEVELOPMENTAL CELL

The role of PR-Set7 in replication licensing depends on Suv4-20h

(2012) D. B. Beck et al.   GENES & DEVELOPMENT

The macrosatellite DXZ4 mediates CTCF-dependent long-range intrachromosomal interactions on the human inactive X chromosome

(2012) Andrea H. Horakova et al.   HUMAN MOLECULAR GENETICS

H3K9 Trimethylation Precedes DNA Methylation during Sheep Oogenesis

(2012) Valentina Russo et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

(2012) Zhonghua Gao et al.   MOLECULAR CELL

Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation

(2012) Jennifer Grant et al.   NATURE

RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation

(2012) Cristina Gontan et al.   NATURE

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

RYBP and Cbx7 Define Specific Biological Functions of Polycomb Complexes in Mouse Embryonic Stem Cells

(2012) Lluis Morey et al.   Cell Reports

The mouse DXZ4 homolog retains Ctcf binding and proximity to Pls3 despite substantial organizational differences compared to the primate macrosatellite

(2012) Andrea H Horakova et al.   GENOME BIOLOGY

A YY1 Bridge for X Inactivation

(2011) Joanne L. Thorvaldsen et al.   CELL

YY1 Tethers Xist RNA to the Inactive X Nucleation Center

(2011) Yesu Jeon et al.   CELL

Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells

(2011) M. Casanova et al.   DEVELOPMENT

Genes that escape from X inactivation

(2011) Joel B. Berletch et al.   HUMAN GENETICS

Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation

(2011) Allison M. Cotton et al.   HUMAN GENETICS

Corepressor Protein CDYL Functions as a Molecular Bridge between Polycomb Repressor Complex 2 and Repressive Chromatin Mark Trimethylated Histone Lysine 27

(2011) Yu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H4K20me3 and HP1  are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells

(2011) T. Wongtawan et al.   JOURNAL OF CELL SCIENCE

N-Terminal Phosphorylation of HP1  Promotes Its Chromatin Binding

(2011) K. Hiragami-Hamada et al.   MOLECULAR AND CELLULAR BIOLOGY

SUV420H2-Mediated H4K20 Trimethylation Enforces RNA Polymerase II Promoter-Proximal Pausing by Blocking hMOF-Dependent H4K16 Acetylation

(2011) P. Kapoor-Vazirani et al.   MOLECULAR AND CELLULAR BIOLOGY

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Predicting protein associations with long noncoding RNAs

(2011) Matteo Bellucci et al.   NATURE METHODS

Regulation of X-chromosome inactivation by the X-inactivation centre

(2011) Sandrine Augui et al.   NATURE REVIEWS GENETICS

Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation

(2011) Anton Wutz   NATURE REVIEWS GENETICS

Evolution from XIST-Independent to XIST-Controlled X-Chromosome Inactivation: Epigenetic Modifications in Distantly Related Mammals

(2011) Julie Chaumeil et al.   PLoS One

Diverse factors are involved in maintaining X chromosome inactivation

(2011) K. M. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

eXIST with matrix-associated proteins

(2011) Shinichi Nakagawa et al.   TRENDS IN CELL BIOLOGY

Histone acetylation controls the inactive X chromosome replication dynamics

(2011) Corella S. Casas-Delucchi et al.   Nature Communications

RNF12 Activates Xist and Is Essential for X Chromosome Inactivation

(2011) Tahsin Stefan Barakat et al.   PLoS Genetics

Identification of regulatory elements flanking human XIST reveals species differences

(2010) Samuel C Chang et al.   BMC MOLECULAR BIOLOGY

A Region of the Human HOXD Cluster that Confers Polycomb-Group Responsiveness

(2010) Caroline J. Woo et al.   CELL

LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation

(2010) Jennifer C. Chow et al.   CELL

The Long Noncoding RNA, Jpx, Is a Molecular Switch for X Chromosome Inactivation

(2010) Di Tian et al.   CELL

The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation

(2010) D. Pullirsch et al.   DEVELOPMENT

The Matrix Protein hnRNP U Is Required for Chromosomal Localization of Xist RNA

(2010) Yuko Hasegawa et al.   DEVELOPMENTAL CELL

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice

(2010) David Llères et al.   EMBO REPORTS

Origin of the polycomb repressive complex 2 and gene silencing by an E(z) homolog in the unicellular alga Chlamydomonas

(2010) Scott Shaver et al.   Epigenetics

Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

(2010) S. Kaneko et al.   GENES & DEVELOPMENT

Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region

(2010) Corinne Chureau et al.   HUMAN MOLECULAR GENETICS

Structural Biology of Human H3K9 Methyltransferases

(2010) Hong Wu et al.   PLoS One

Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation

(2010) Willem Rens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)

(2010) C. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X chromosome-wide analyses of genomic DNA methylation states and gene expression in male and female neutrophils

(2010) Yukio Yasukochi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2-D Structure of the A Region of Xist RNA and Its Implication for PRC2 Association

(2010) Sylvain Maenner et al.   PLOS BIOLOGY

RNF12 Is an X-Encoded Dose-Dependent Activator of X Chromosome Inactivation

(2009) Iris Jonkers et al.   CELL

Specific patterns of histone marks accompany X chromosome inactivation in a marsupial

(2009) Edda Koina et al.   CHROMOSOME RESEARCH

SATB1 Defines the Developmental Context for Gene Silencing by Xist in Lymphoma and Embryonic Cells

(2009) Ruben Agrelo et al.   DEVELOPMENTAL CELL

Social function in multiple X and Y chromosome disorders: XXY, XYY, XXYY, XXXY

(2009) Jeannie Visootsak et al.   Developmental Disabilities Research Reviews

Satb1 and Satb2 regulate embryonic stem cell differentiation andNanogexpression

(2009) Fabio Savarese et al.   GENES & DEVELOPMENT

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

(2009) M. J. Gamble et al.   GENES & DEVELOPMENT

High-resolution analysis of epigenetic changes associated with X inactivation

(2009) H. Marks et al.   GENOME RESEARCH

Multimerization and H3K9me3 Binding Are Required for CDYL1b Heterochromatin Association

(2009) Henriette Franz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation

(2009) Sundeep Kalantry et al.   NATURE

Studying Early Lethality of 45,XO (Turner's Syndrome) Embryos Using Human Embryonic Stem Cells

(2009) Achia Urbach et al.   PLoS One

CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features

(2009) Kobby Essien et al.   GENOME BIOLOGY

ATRX marks the inactive X chromosome (Xi) in somatic cells and during imprinted X chromosome inactivation in trophoblast stem cells

(2008) Claudia Baumann et al.   CHROMOSOMA

Weak but Uniform Enrichment of the Histone Variant macroH2A1 along the Inactive X Chromosome

(2008) F. Mietton et al.   MOLECULAR AND CELLULAR BIOLOGY

Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms

(2008) Raphael Margueron et al.   MOLECULAR CELL

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

(2008) Marnie E Blewitt et al.   NATURE GENETICS

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS

A Dual Origin of the Xist Gene from a Protein-Coding Gene and a Set of Transposable Elements

(2008) Eugeny A. Elisaphenko et al.   PLoS One

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE