Naturally Killing the Silent Killer: NK Cell-Based Immunotherapy for Ovarian Cancer
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Title
Naturally Killing the Silent Killer: NK Cell-Based Immunotherapy for Ovarian Cancer
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-08-09
DOI
10.3389/fimmu.2019.01782
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Note: Only part of the references are listed.- Cytokine-induced memory-like natural killer cells have enhanced function, proliferation, and in vivo expansion against ovarian cancer cells
- (2019) Locke D. Uppendahl et al. GYNECOLOGIC ONCOLOGY
- Characterization of a Novel Third-Generation Anti-CD24-CAR against Ovarian Cancer
- (2019) Rüdiger Klapdor et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells
- (2019) Takahiro Kamiya et al. JOURNAL OF CLINICAL INVESTIGATION
- Setting traps for NKG2A gives NK cell immunotherapy a fighting chance
- (2019) Frank Cichocki et al. JOURNAL OF CLINICAL INVESTIGATION
- Cancer Immunotherapy: Factors Important for the Evaluation of Safety in Nonclinical Studies
- (2018) Danuta J. Herzyk et al. AAPS Journal
- Mechanisms of resistance to immune checkpoint inhibitors
- (2018) Russell W Jenkins et al. BRITISH JOURNAL OF CANCER
- Ovarian cancer statistics, 2018
- (2018) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
- (2018) Ye Li et al. Cell Stem Cell
- Tumor immunotherapy: New aspects of natural killer cells
- (2018) Yangxi Li et al. Chinese Journal of Cancer Research
- Natural killer cell education in human health and disease
- (2018) Jeanette E Boudreau et al. CURRENT OPINION IN IMMUNOLOGY
- Diagnostic and Prognostic Biomarkers in ovarian cancer and the potential roles of cancer stem cells – An updated review
- (2018) Thingreila Muinao et al. EXPERIMENTAL CELL RESEARCH
- FORWARD I: a Phase III study of mirvetuximab soravtansine versus chemotherapy in platinum-resistant ovarian cancer
- (2018) Kathleen N Moore et al. Future Oncology
- Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity
- (2018) Qing Zhang et al. NATURE IMMUNOLOGY
- Understanding the tumor immune microenvironment (TIME) for effective therapy
- (2018) Mikhail Binnewies et al. NATURE MEDICINE
- Natural Killer Cell Education and the Response to Infection and Cancer Therapy: Stay Tuned
- (2018) Jeanette E. Boudreau et al. TRENDS IN IMMUNOLOGY
- CAR-T cells: the long and winding road to solid tumors
- (2018) Maria Michela D’Aloia et al. Cell Death & Disease
- Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells
- (2018) Yunlong Zhao et al. Cell Reports
- Expanded CD56superbrightCD16+ NK cells from ovarian cancer patients are cytotoxic against autologous tumor in a patient-derived xenograft murine model
- (2018) Sophie M Poznanski et al. Cancer Immunology Research
- Adaptive NK Cells Resist Regulatory T-cell Suppression Driven by IL37
- (2018) Dhifaf Sarhan et al. Cancer Immunology Research
- Chimeric Antigen Receptor Expressing Natural Killer Cells for the Immunotherapy of Cancer
- (2018) Rohtesh S. Mehta et al. Frontiers in Immunology
- Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor
- (2018) Silvia Gaggero et al. OncoImmunology
- Quantity and Quality Reconstitution of NKG2A+ Natural Killer Cells Are Associated with Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation
- (2018) Li-Juan Hu et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade
- (2018) Joy Hsu et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor Antigen Escape from CAR T-cell Therapy
- (2018) Robbie G. Majzner et al. Cancer Discovery
- In Silico Analysis of the Minor Histocompatibility Antigen Landscape Based on the 1000 Genomes Project
- (2018) Nadia A. Bykova et al. Frontiers in Immunology
- Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells
- (2018) Pascale André et al. CELL
- An antibody designed to improve adoptive NK-cell therapy inhibits pancreatic cancer progression in a murine model
- (2018) Jaemin Lee et al. Cancer Immunology Research
- Allogeneic CAR-T Cells: More than Ease of Access?
- (2018) Charlotte Graham et al. Cells
- Antibody–drug conjugates for ovarian cancer
- (2018) Daphne Stewart et al. CURRENT OPINION IN OBSTETRICS & GYNECOLOGY
- NY-ESO-1 expression predicts an aggressive phenotype of ovarian cancer
- (2017) J. Brian Szender et al. GYNECOLOGIC ONCOLOGY
- IL-15 super-agonist (ALT-803) enhances natural killer (NK) cell function against ovarian cancer
- (2017) M. Felices et al. GYNECOLOGIC ONCOLOGY
- The potential and promise of IL-15 in immuno-oncogenic therapies
- (2017) Tanya O. Robinson et al. IMMUNOLOGY LETTERS
- PD-1/PD-L1 Blockade Therapy for Tumors with Downregulated MHC Class I Expression
- (2017) Michal Šmahel INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization
- (2017) Silvia Pesce et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- KIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation
- (2017) Jeanette E. Boudreau et al. JOURNAL OF CLINICAL ONCOLOGY
- A distinct innate lymphoid cell population regulates tumor-associated T cells
- (2017) Sarah Q Crome et al. NATURE MEDICINE
- Increased expression of programmed cell death protein 1 on NK cells inhibits NK-cell-mediated anti-tumor function and indicates poor prognosis in digestive cancers
- (2017) Y Liu et al. ONCOGENE
- The immunopeptidomic landscape of ovarian carcinomas
- (2017) Heiko Schuster et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FDA Approves Second CAR T-cell Therapy
- (2017) Cancer Discovery
- Immune Cell Population in Ovarian Tumor Microenvironment
- (2017) Dong Li Cai et al. Journal of Cancer
- Natural Killer Cells in Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation
- (2017) Federico Simonetta et al. Frontiers in Immunology
- Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance
- (2017) Alessandra Zingoni et al. Frontiers in Immunology
- Improved migration of tumor ascites lymphocytes to ovarian cancer microenvironment by CXCR2 transduction
- (2017) Manja Idorn et al. OncoImmunology
- Checkpoint Inhibition of KIR2D with the Monoclonal Antibody IPH2101 Induces Contraction and Hyporesponsiveness of NK Cells in Patients with Myeloma
- (2016) M. Carlsten et al. CLINICAL CANCER RESEARCH
- Targeting the programmed cell death-1 pathway in breast and ovarian cancer
- (2016) Leisha A. Emens et al. CURRENT OPINION IN OBSTETRICS & GYNECOLOGY
- Combined Immunoscore of CD103 and CD3 Identifies Long-Term Survivors in High-Grade Serous Ovarian Cancer
- (2016) Hans-Christian Bösmüller et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- KIR3DL1 Allelic Polymorphism and HLA-B Epitopes Modulate Response to Anti-GD2 Monoclonal Antibody in Patients With Neuroblastoma
- (2016) Christopher J. Forlenza et al. JOURNAL OF CLINICAL ONCOLOGY
- IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function
- (2016) Yin Guo et al. JOURNAL OF IMMUNOLOGY
- NK Cells Restrain Spontaneous Antitumor CD8+T Cell Priming through PD-1/PD-L1 Interactions with Dendritic Cells
- (2016) Ximena L. Raffo Iraolagoitia et al. JOURNAL OF IMMUNOLOGY
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
- (2016) Rizwan Romee et al. Science Translational Medicine
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- (2016) Valsamo Anagnostou et al. Cancer Discovery
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- (2016) Kamila Kloudová et al. Oncotarget
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- (2016) Caroline Jochems et al. Oncotarget
- PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma
- (2016) Asma Beldi-Ferchiou et al. Oncotarget
- Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines
- (2016) Spencer D. Martin et al. PLoS One
- NK-92: an ‘off-the-shelf therapeutic’ for adoptive natural killer cell-based cancer immunotherapy
- (2015) Garnet Suck et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- How Do Cytotoxic Lymphocytes Kill Cancer Cells?
- (2015) L. Martinez-Lostao et al. CLINICAL CANCER RESEARCH
- A Phase I Trial of the Anti-KIR Antibody IPH2101 and Lenalidomide in Patients with Relapsed/Refractory Multiple Myeloma
- (2015) D. M. Benson et al. CLINICAL CANCER RESEARCH
- Efficacy and safety of cord blood–derived cytokine-induced killer cells in treatment of patients with malignancies
- (2015) Zhen Zhang et al. CYTOTHERAPY
- Immunological changes in the ascites of cancer patients after intraperitoneal administration of the bispecific antibody catumaxomab (anti-EpCAM×anti-CD3)
- (2015) Marco Fossati et al. GYNECOLOGIC ONCOLOGY
- Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function
- (2015) Heinrich Schlums et al. IMMUNITY
- Epigenetic Modification and Antibody-Dependent Expansion of Memory-like NK Cells in Human Cytomegalovirus-Infected Individuals
- (2015) Jaewon Lee et al. IMMUNITY
- Safety and Antitumor Activity of Anti–PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer
- (2015) Junzo Hamanishi et al. JOURNAL OF CLINICAL ONCOLOGY
- Landscape of Tumor Antigens in T Cell Immunotherapy
- (2015) S. Ilyas et al. JOURNAL OF IMMUNOLOGY
- A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16ecto directed chimeric antigen receptors for recurrent ovarian cancer
- (2015) Mythili Koneru et al. Journal of Translational Medicine
- IMGN853, a Folate Receptor- (FR )-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FR -Expressing Tumors
- (2015) O. Ab et al. MOLECULAR CANCER THERAPEUTICS
- Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
- (2015) E. M. Van Allen et al. SCIENCE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- B7-H6-mediated downregulation of NKp30 in NK cells contributes to ovarian carcinoma immune escape
- (2015) Silvia Pesce et al. OncoImmunology
- Abstract 650: KIR/HLA interactions negatively affect rituximab, but not GA101 (obinutuzumab)-induced ADCC
- (2015) Grzegorz Terszowski et al. CANCER RESEARCH
- Expansion and Homing of Adoptively Transferred Human Natural Killer Cells in Immunodeficient Mice Varies with Product Preparation and In Vivo Cytokine Administration: Implications for Clinical Therapy
- (2014) Jeffrey S. Miller et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets
- (2014) M. K. Gleason et al. BLOOD
- Activated regulatory and memory T-cells accumulate in malignant ascites from ovarian carcinoma patients
- (2014) Johannes Landskron et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Ultra Low-Dose IL-2 for GVHD Prophylaxis after Allogeneic Hematopoietic Stem Cell Transplantation Mediates Expansion of Regulatory T Cells without Diminishing Antiviral and Antileukemic Activity
- (2014) A. A. Kennedy-Nasser et al. CLINICAL CANCER RESEARCH
- TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells
- (2014) Francesca Bellora et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival
- (2014) S. D. Brown et al. GENOME RESEARCH
- TGF- Utilizes SMAD3 to Inhibit CD16-Mediated IFN- Production and Antibody-Dependent Cellular Cytotoxicity in Human NK Cells
- (2014) R. Trotta et al. JOURNAL OF IMMUNOLOGY
- Macrophage Migration Inhibitory Factor Contributes to the Immune Escape of Ovarian Cancer by Down-Regulating NKG2D
- (2014) M. Krockenberger et al. JOURNAL OF IMMUNOLOGY
- Maintenance Therapy With Autologous Cytokine-induced Killer Cells in Patients With Advanced Epithelial Ovarian Cancer After First-line Treatment
- (2014) Jun Liu et al. JOURNAL OF IMMUNOTHERAPY
- Human Cytomegalovirus Drives Epigenetic Imprinting of the IFNG Locus in NKG2Chi Natural Killer Cells
- (2014) Merlin Luetke-Eversloh et al. PLoS Pathogens
- Recent Concepts of Ovarian Carcinogenesis: Type I and Type II
- (2014) Masafumi Koshiyama et al. Biomed Research International
- Reversal of NK-Cell Exhaustion in Advanced Melanoma by Tim-3 Blockade
- (2014) I. P. da Silva et al. Cancer Immunology Research
- STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression
- (2014) Nina Le Bert et al. OncoImmunology
- Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies
- (2013) H. E. Kohrt et al. BLOOD
- Surveillance of the Tumor Mutanome by T Cells during Progression from Primary to Recurrent Ovarian Cancer
- (2013) Darin A. Wick et al. CLINICAL CANCER RESEARCH
- Tumor-Infiltrating Lymphocytes Expressing the Tissue Resident Memory Marker CD103 Are Associated with Increased Survival in High-Grade Serous Ovarian Cancer
- (2013) J. R. Webb et al. CLINICAL CANCER RESEARCH
- Chimeric NKG2D CAR-Expressing T Cell-Mediated Attack of Human Ovarian Cancer Is Enhanced by Histone Deacetylase Inhibition
- (2013) De-Gang Song et al. HUMAN GENE THERAPY
- Trastuzumab mediates antibody-dependent cell-mediated cytotoxicity and phagocytosis to the same extent in both adjuvant and metastatic HER2/neu breast cancer patients
- (2013) Branka Petricevic et al. Journal of Translational Medicine
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Genetic and Environmental Determinants of Human NK Cell Diversity Revealed by Mass Cytometry
- (2013) A. Horowitz et al. Science Translational Medicine
- Natural killer cells: walking three paths down memory lane
- (2013) Gundula Min-Oo et al. TRENDS IN IMMUNOLOGY
- Epigenetic regulation of NK cell differentiation and effector functions
- (2013) Frank Cichocki et al. Frontiers in Immunology
- Combination Immune Therapies to Enhance Anti-Tumor Responses by NK Cells
- (2013) Ashley Mentlik James et al. Frontiers in Immunology
- Dynamics of T-cell infiltration during the course of ovarian cancer: The gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells
- (2012) Anna Fialová et al. INTERNATIONAL JOURNAL OF CANCER
- Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment
- (2012) Nidale Tarek et al. JOURNAL OF CLINICAL INVESTIGATION
- Prognostically relevant gene signatures of high-grade serous ovarian carcinoma
- (2012) Roel G.W. Verhaak et al. JOURNAL OF CLINICAL INVESTIGATION
- A phase I clinical trial of adoptive transfer of folate receptor-alpha redirected autologous T cells for recurrent ovarian cancer
- (2012) Lana E Kandalaft et al. Journal of Translational Medicine
- Cancer classification using the Immunoscore: a worldwide task force
- (2012) Jérôme Galon et al. Journal of Translational Medicine
- Exploiting a natural conformational switch to engineer an interleukin-2 ‘superkine’
- (2012) Aron M. Levin et al. NATURE
- Membrane-Bound IL-21 Promotes Sustained Ex Vivo Proliferation of Human Natural Killer Cells
- (2012) Cecele J. Denman et al. PLoS One
- Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features
- (2012) Jaime Prat VIRCHOWS ARCHIV
- Long-term proliferation of functional human NK cells, with conversion of CD56dim NK cells to a CD56bright phenotype, induced by carcinoma cells co-expressing 4-1BBL and IL-12
- (2011) Alexander C. Dowell et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The unique profile of cord blood natural killer cells balances incomplete maturation and effective killing function upon activation
- (2011) Martha Luevano et al. HUMAN IMMUNOLOGY
- Natural Killer Cells and Solid Tumors
- (2011) Ana Stojanovic et al. Journal of Innate Immunity
- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis
- (2011) W. Glenn McCluggage PATHOLOGY
- Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity
- (2011) Erica B. Wilson et al. PLoS One
- HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8+ T lymphocytes
- (2011) M. Gooden et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytokines in Cancer Immunotherapy
- (2011) Sylvia Lee et al. Cancers
- Allogeneic natural killer cells for refractory lymphoma
- (2010) Veronika Bachanova et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Chemotherapy-Induced Genotoxic Stress Promotes Sensitivity to Natural Killer Cell Cytotoxicity by Enabling Missing-Self Recognition
- (2010) J. H. Fine et al. CANCER RESEARCH
- Augmenting Therapy of Ovarian Cancer Efficacy by Secreting IL-21 Human Umbilical Cord Blood Stem Cells in Nude Mice
- (2010) Weihua Hu et al. CELL TRANSPLANTATION
- CD24: from A to Z
- (2010) Xianfeng Fang et al. Cellular & Molecular Immunology
- Successful Eradication of Established Peritoneal Ovarian Tumors in SCID-Beige Mice following Adoptive Transfer of T Cells Genetically Targeted to the MUC16 Antigen
- (2010) A. A. Chekmasova et al. CLINICAL CANCER RESEARCH
- A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer
- (2010) Melissa A. Geller et al. CYTOTHERAPY
- NK cell dysfunction with down-regulated CD16 and up-regulated CD56 molecules in patients with esophageal squamous cell carcinoma
- (2010) M. Watanabe et al. DISEASES OF THE ESOPHAGUS
- Ovarian cancer creates a suppressive microenvironment to escape immune elimination
- (2010) Refika Yigit et al. GYNECOLOGIC ONCOLOGY
- MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells
- (2010) Jennifer AA Gubbels et al. Molecular Cancer
- "Self"-reflection by KIR
- (2009) S. Cooley et al. BLOOD
- Maintenance immunotherapy in recurrent ovarian cancer: Long term follow-up of a phase II study
- (2009) Francesco Recchia et al. GYNECOLOGIC ONCOLOGY
- Primary Human Tumor Cells Expressing CD155 Impair Tumor Targeting by Down-Regulating DNAM-1 on NK Cells
- (2009) M. Carlsten et al. JOURNAL OF IMMUNOLOGY
- Enhanced In Vivo Growth of Lymphoma Tumors in the Absence of the NK-Activating Receptor NKp46/NCR1
- (2009) G. G. Halfteck et al. JOURNAL OF IMMUNOLOGY
- Adaptive immune features of natural killer cells
- (2009) Joseph C. Sun et al. NATURE
- Human natural killer cells
- (2008) M. A. Caligiuri BLOOD
- Transforming Growth Factor- 1, Transforming Growth Factor- 2, and Transforming Growth Factor- 3 Enhance Ovarian Cancer Metastatic Potential by Inducing a Smad3-Dependent Epithelial-to-Mesenchymal Transition
- (2008) T.-V. Do et al. MOLECULAR CANCER RESEARCH
- HLA alleles determine differences in human natural killer cell responsiveness and potency
- (2008) S. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
- (2008) F. S. Hodi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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