Periodic Oxaliplatin Administration in Synergy with PER2‐Mediated PCNA Transcription Repression Promotes Chronochemotherapeutic Efficacy of OSCC

Hyperthermic intraperitoneal chemotherapy with oxaliplatin for peritoneal carcinomatosis: a clinical pharmacological perspective on a surgical procedure.

(2018) Loek A.W. de Jong et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer

(2018) Carolina Moretto Carnielli et al.   Nature Communications

Rhythmic expressed clock regulates the transcription of proliferating cellular nuclear antigen in teleost retina

(2017) Hang Song et al.   EXPERIMENTAL EYE RESEARCH

MALAT1 Is Associated with Poor Response to Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients and Promotes Chemoresistance through EZH2

(2017) Peilong Li et al.   MOLECULAR CANCER THERAPEUTICS

Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork

(2017) Katherine N. Choe et al.   MOLECULAR CELL

An assay to detect DNA-damaging agents that induce nucleotide excision-repairable DNA lesions in living human cells

(2017) Reine Takatsuka et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Synergistic antitumor effects of the combined treatment with an HDAC6 inhibitor and a COX-2 inhibitor through activation of PTEN

(2017) Guanhua Zhang et al.   ONCOLOGY REPORTS

Systems Chronotherapeutics

(2017) Annabelle Ballesta et al.   PHARMACOLOGICAL REVIEWS

The Circadian Clock Gene Bmal1 Controls Thyroid Hormone-Mediated Spectral Identity and Cone Photoreceptor Function

(2017) Onkar B. Sawant et al.   Cell Reports

Pharmacokinetic interaction between taxanes and amiodarone leading to severe toxicity

(2016) Felix Hammann et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis

(2016) Nicole M. Kettner et al.   CANCER CELL

Circadian Clock GeneBmal1Inhibits Tumorigenesis and Increases Paclitaxel Sensitivity in Tongue Squamous Cell Carcinoma

(2016) Qingming Tang et al.   CANCER RESEARCH

Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing

(2016) Jianwei Wang et al.   NATURE CELL BIOLOGY

Transcriptional architecture of the mammalian circadian clock

(2016) Joseph S. Takahashi   NATURE REVIEWS GENETICS

Mammalian Period represses and de-represses transcription by displacing CLOCK–BMAL1 from promoters in a Cryptochrome-dependent manner

(2016) Yi-Ying Chiou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian physiology of metabolism

(2016) Satchidananda Panda   SCIENCE

Epigenetic activation of the drug transporter OCT2 sensitizes renal cell carcinoma to oxaliplatin

(2016) Yanqing Liu et al.   Science Translational Medicine

Dosing-Time Makes the Poison: Circadian Regulation and Pharmacotherapy

(2016) Robert Dallmann et al.   TRENDS IN MOLECULAR MEDICINE

PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs

(2016) Lili Chen et al.   Scientific Reports

The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response

(2016) Anna Brestovitsky et al.   PLoS Pathogens

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tumor-Related Molecular Mechanisms of Oxaliplatin Resistance

(2015) E. Martinez-Balibrea et al.   MOLECULAR CANCER THERAPEUTICS

Nucleotide excision repair efficiency in quiescent human fibroblasts is modulated by circadian clock

(2015) Leonardo Bee et al.   NUCLEIC ACIDS RESEARCH

Circadian and Melatonin Disruption by Exposure to Light at Night Drives Intrinsic Resistance to Tamoxifen Therapy in Breast Cancer

(2014) R. T. Dauchy et al.   CANCER RESEARCH

Thoracic surface temperature rhythms as circadian biomarkers for cancer chronotherapy

(2014) Véronique Pasquale Roche et al.   CHRONOBIOLOGY INTERNATIONAL

Circadian Clock Proteins and Immunity

(2014) Anne M. Curtis et al.   IMMUNITY

A Small Molecule Inhibitor of Monoubiquitinated Proliferating Cell Nuclear Antigen(PCNA) Inhibits Repair of Interstrand DNA Cross-link, Enhances DNA Double Strand Break, and Sensitizes Cancer Cells to Cisplatin

(2014) Akira Inoue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1

(2014) T.-H. Kang et al.   NUCLEIC ACIDS RESEARCH

PCNA: a silent housekeeper or a potential therapeutic target?

(2014) Shao-Chun Wang   TRENDS IN PHARMACOLOGICAL SCIENCES

Low-dose prednisone chronotherapy for rheumatoid arthritis: a randomised clinical trial (CAPRA-2)

(2013) Frank Buttgereit et al.   ANNALS OF THE RHEUMATIC DISEASES

Overexpression of the Circadian Clock Gene Bmal1 Increases Sensitivity to Oxaliplatin in Colorectal Cancer

(2013) Z.-l. Zeng et al.   CLINICAL CANCER RESEARCH

The circadian clock and cell cycle: interconnected biological circuits

(2013) Selma Masri et al.   CURRENT OPINION IN CELL BIOLOGY

Role of Circadian Clocks in the Development and Therapeutics of Cancer

(2013) X-L Huang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Regulation of PCNA–protein interactions for genome stability

(2013) Niels Mailand et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sex moderates circadian chemotherapy effects on survival of patients with metastatic colorectal cancer: a meta-analysis

(2012) S. Giacchetti et al.   ANNALS OF ONCOLOGY

Cell-autonomous circadian DNA damage response

(2012) Roman V. Kondratov   CELL CYCLE

Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis

(2012) M. Geyfman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recurrent Oral Cancer: Current and Emerging Therapeutic Approaches

(2012) Sabrina Daniela da Silva et al.   Frontiers in Pharmacology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Role of Endonucleases XPF and XPG in Nucleotide Excision Repair of Platinated DNA and Cisplatin/Oxaliplatin Cytotoxicity

(2011) Nora Graf et al.   CHEMBIOCHEM

Control of skin cancer by the circadian rhythm

(2011) S. Gaddameedhi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Timing in Cancer Treatments

(2010) Francis Lévi et al.   Annual Review of Pharmacology and Toxicology

Circadian rhythms and cancer

(2010) Sigal Gery et al.   CELL CYCLE

Identification of cisplatin-resistance related genes in head and neck squamous cell carcinoma

(2009) Yukio Yamano et al.   INTERNATIONAL JOURNAL OF CANCER

Eukaryotic Translesion Polymerases and Their Roles and Regulation in DNA Damage Tolerance

(2009) L. S. Waters et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

Induction of Cancer Metastasis by Cyclophosphamide Pretreatment of Host Mice: An Opposite Effect of Chemotherapy

(2008) K. Yamauchi et al.   CANCER RESEARCH

Glucocorticoid chronotherapy in rheumatoid arthritis

(2008) Johannes WJ Bijlsma et al.   LANCET

Implications of circadian clocks for the rhythmic delivery of cancer therapeutics

(2008) F. Levi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES