TGF-β2 Induces Gli1 in a Smad3-Dependent Manner Against Cerebral Ischemia/Reperfusion Injury After Isoflurane Post-conditioning in Rats

Neuronal Transforming Growth Factor beta Signaling via SMAD3 Contributes to Pain in Animal Models of Chronic Pancreatitis

(2018) Liansheng Liu et al.   GASTROENTEROLOGY

Isoflurane preconditioning inhibits the effects of tissue-type plasminogen activator on brain endothelial cell in an in vitro model of ischemic stroke

(2017) So Yeong Cheon et al.   International Journal of Medical Sciences

TRAIL, Wnt, Sonic Hedgehog, TGFβ, and miRNA Signalings Are Potential Targets for Oral Cancer Therapy

(2017) Ammad Farooqi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Salvianolic Acids for Injection (SAFI) promotes functional recovery and neurogenesis via sonic hedgehog pathway after stroke in mice

(2017) Ye Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

TGF-β receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis

(2017) Salih Gencer et al.   Science Signaling

Poststroke Sonic Hedgehog Agonist Treatment Improves Functional Recovery by Enhancing Neurogenesis and Angiogenesis

(2017) Yongming Jin et al.   STROKE

Resveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathway

(2017) Ching-Long Chen et al.   Drug Design Development and Therapy

TGF-β receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis

(2017) Salih Gencer et al.   Science Signaling

The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc

(2016) Ruifang Liang et al.   ANNALS OF THE RHEUMATIC DISEASES

Transforming growth-beta 1 contributes to isoflurane postconditioning against cerebral ischemia–reperfusion injury by regulating the c-Jun N-terminal kinase signaling pathway

(2016) Sheng Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung

(2016) Timo H. Lüdtke et al.   DEVELOPMENTAL CELL

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Haidong Wang et al.   LANCET

Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages

(2016) Beate M. Lichtenberger et al.   Nature Communications

Isoflurano fornece neuroproteção em lesão cerebral hipóxico‐isquêmica neonatal por inibição da apoptose

(2016) De‐An Zhao et al.   Revista Brasileira de Anestesiologia

Reemergence of Hedgehog Mediates Epithelial–Mesenchymal Crosstalk in Pulmonary Fibrosis

(2015) Biao Hu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Effect of Electroacupuncture on Cell Apoptosis and ERK Signal Pathway in the Hippocampus of Adult Rats with Cerebral Ischemia-Reperfusion

(2015) Chunxiao Wu et al.   Evidence-based Complementary and Alternative Medicine

Isoflurane reduces the ischemia reperfusion injury surge: A longitudinal study with MRI

(2014) Saeid Taheri et al.   BRAIN RESEARCH

Network Modeling of TGF  Signaling in Hepatocellular Carcinoma Epithelial-to-Mesenchymal Transition Reveals Joint Sonic Hedgehog and Wnt Pathway Activation

(2014) S. N. Steinway et al.   CANCER RESEARCH

TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons

(2014) Mahesh Kandasamy et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Gli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor β1 in mice

(2014) Matthew McMillin et al.   JOURNAL OF HEPATOLOGY

Sonic hedgehog signaling in the postnatal brain

(2014) Arturo Álvarez-Buylla et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury

(2014) O V Chechneva et al.   Cell Death & Disease

Activin and TGF-β Effects on Brain Development and Neural Stem Cells

(2013) Griselda Rodriguez-Martinez et al.   CNS & Neurological Disorders-Drug Targets

Only scratching the cell surface: extracellular signals in cerebrum development

(2013) Jean M Hébert   CURRENT OPINION IN GENETICS & DEVELOPMENT

Anti-oxidative, anti-apoptotic, and pro-angiogenic effects mediate functional improvement by sonic hedgehog against focal cerebral ischemia in rats

(2013) Shiang-Suo Huang et al.   EXPERIMENTAL NEUROLOGY

The Sonic Hedgehog Pathway Mediates Brain Plasticity and Subsequent Functional Recovery After Bone Marrow Stromal Cell Treatment of Stroke in Mice

(2013) Xiaoshuang Ding et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010

(2013) Valery L Feigin et al.   LANCET

Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner

(2013) Jianjun Lei et al.   Molecular Cancer

Sonic Hedgehog Signaling Pathway Mediates Cerebrolysin-Improved Neurological Function After Stroke

(2013) Li Zhang et al.   STROKE

Crosstalk between TGF-β and hedgehog signaling in cancer

(2012) Delphine Javelaud et al.   FEBS LETTERS

Expression of Microphthalmia-associated Transcription Factor (MITF), Which Is Critical for Melanoma Progression, Is Inhibited by Both Transcription Factor GLI2 and Transforming Growth Factor-β

(2012) Marie-Jeanne Pierrat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF- /SMAD/GLI2 Signaling Axis in Cancer Progression and Metastasis

(2011) D. Javelaud et al.   CANCER RESEARCH

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Intermittent Hypobaric Hypoxia Preconditioning Induced Brain Ischemic Tolerance by Up-Regulating Glial Glutamate Transporter-1 in Rats

(2011) Shu-Juan Gong et al.   NEUROCHEMICAL RESEARCH

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

(2011) J. I. Alvarez et al.   SCIENCE

Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy

(2010) J. Li et al.   DIABETES

Requirement of TGFβ Signaling for SMO-mediated Carcinogenesis

(2010) Qipeng Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

(2009) O. Nolan-Stevaux et al.   GENES & DEVELOPMENT

Cloning of the HumanGLI2Promoter

(2009) Sylviane Dennler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotection of microglial conditioned medium on 6-hydroxydopamine-induced neuronal death: role of transforming growth factor beta-2

(2009) Elisabetta Polazzi et al.   JOURNAL OF NEUROCHEMISTRY

Sonic Hedgehog Regulates Ischemia/Hypoxia-Induced Neural Progenitor Proliferation

(2009) John R. Sims et al.   STROKE

Transient Cerebral Ischemia Leads to TGF-β2 Expression in Golgi Apparatus Organelles

(2008) Zhiping Hu et al.   CURRENT NEUROVASCULAR RESEARCH

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

Attenuation of Notch signaling promotes the differentiation of neural progenitors into neurons in the hippocampal CA1 region after ischemic injury

(2008) S. Oya et al.   NEUROSCIENCE