Magnetic targeting of adoptively transferred tumour-specific nanoparticle-loaded CD8+ T cells does not improve their tumour infiltration in a mouse model of cancer but promotes the retention of these cells in tumour-draining lymph nodes

T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field

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The Lymphatic System in Disease Processes and Cancer Progression

(2016) Timothy P. Padera et al.   Annual Review of Biomedical Engineering

Adoptive cell therapy: a highly successful individualized therapy for melanoma with great potential for other malignancies

(2016) Els ME Verdegaal   CURRENT OPINION IN IMMUNOLOGY

Metal oxide nanoparticles interact with immune cells and activate different cellular responses

(2016) Rosana Simón-Vázquez et al.   International Journal of Nanomedicine

Killers on sterols

(2016) Michael L. Dustin   NATURE

Magnetic Enrichment of Dendritic Cell Vaccine in Lymph Node with Fluorescent-Magnetic Nanoparticles Enhanced Cancer Immunotherapy

(2016) Honglin Jin et al.   Theranostics

Nanoparticles and antigen-specific T-cell therapeutics: a comprehensive study on uptake and release

(2015) Oliver Zupke et al.   Nanomedicine

An effective strategy of magnetic stem cell delivery for spinal cord injury therapy

(2015) Dmitry Tukmachev et al.   Nanoscale

Labelling dendritic cells with SPIO has implications for their subsequentin vivomigration as assessed with cellular MRI

(2015) Sonali N. de Chickera et al.   Contrast Media & Molecular Imaging

Combining α-Radioimmunotherapy and Adoptive T Cell Therapy to Potentiate Tumor Destruction

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Magnetic Field-Induced T Cell Receptor Clustering by Nanoparticles Enhances T Cell Activation and Stimulates Antitumor Activity

(2014) Karlo Perica et al.   ACS Nano

Nanomedicine in autoimmunity

(2014) Xavier Clemente-Casares et al.   IMMUNOLOGY LETTERS

Radiation-Induced CXCL16 Release by Breast Cancer Cells Attracts Effector T Cells

(2014) S. Matsumura et al.   JOURNAL OF IMMUNOLOGY

Focused Ultrasound Delivers Targeted Immune Cells to Metastatic Brain Tumors

(2013) R. Alkins et al.   CANCER RESEARCH

Cancer immunotherapies, their safety and toxicity

(2013) Gheath Alatrash et al.   Expert Opinion On Drug Safety

Elevated CD3+ and CD8+ tumor-infiltrating immune cells correlate with prolonged survival in glioblastoma patients despite integrated immunosuppressive mechanisms in the tumor microenvironment and at the systemic level

(2013) Justyna Kmiecik et al.   JOURNAL OF NEUROIMMUNOLOGY

Different cell responses induced by exposure to maghemite nanoparticles

(2013) Yurena Luengo et al.   Nanoscale

Cell labeling with magnetic nanoparticles: Opportunity for magnetic cell imaging and cell manipulation

(2013) Jelena Kolosnjaj-Tabi et al.   JOURNAL OF NANOBIOTECHNOLOGY

Blockade of PD-1 immunosuppression boosts CAR T-cell therapy

(2013) Liza B John et al.   OncoImmunology

Ways to Enhance Lymphocyte Trafficking into Tumors and Fitness of Tumor Infiltrating Lymphocytes

(2013) Matteo Bellone et al.   Frontiers in Oncology

Tumor-infiltrating Lymphocytes, Tumor Characteristics, and Recurrence in Patients With Early Breast Cancer

(2012) Seung Tae Kim et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles

(2012) Eue-Soon Jang et al.   BIOMATERIALS

Tumoral Lymphocytic Infiltration and Expression of the Chemokine CXCL10 in Breast Cancers from the Ontario Familial Breast Cancer Registry

(2012) A. M. Mulligan et al.   CLINICAL CANCER RESEARCH

Migration of iron-labeled KHYG-1 natural killer cells to subcutaneous tumors in nude mice, as detected by magnetic resonance imaging

(2012) Christiane L. Mallett et al.   CYTOTHERAPY

Surface Charge Affects Cellular Uptake and Intracellular Trafficking of Chitosan-Based Nanoparticles

(2011) Zhan-Guo Yue et al.   BIOMACROMOLECULES

Dimercaptosuccinic acid-coated magnetite nanoparticles for magnetically guided in vivo delivery of interferon gamma for cancer immunotherapy

(2011) Raquel Mejías et al.   BIOMATERIALS

Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control

(2011) M. Hong et al.   CANCER RESEARCH

Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy

(2011) S. A. Rosenberg et al.   CLINICAL CANCER RESEARCH

Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions

(2011) Jeffrey C Nolz et al.   Immunotherapy

Peripheral T Cells Re-Enter the Thymus and Interfere with Central Tolerance Induction

(2011) S. L. Edelmann et al.   JOURNAL OF IMMUNOLOGY

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials

(2011) Feng Zhao et al.   Small

The use of mouse models to better understand mechanisms of autoimmunity and tolerance

(2010) Fumi Miyagawa et al.   JOURNAL OF AUTOIMMUNITY

Depicting adoptive immunotherapy for prostate cancer in an animal model with magnetic resonance imaging

(2010) Reinhard Meier et al.   MAGNETIC RESONANCE IN MEDICINE

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

Time-varied magnetic field enhances transport of magnetic nanoparticles in viscous gel

(2009) Cristin MacDonald et al.   Nanomedicine

Effect of Surface Properties on Nanoparticle–Cell Interactions

(2009) Ayush Verma et al.   Small

Preparation of human immune effector T cells containing iron-oxide nanoparticles

(2008) Hironori Iida et al.   BIOTECHNOLOGY AND BIOENGINEERING

Minimally Cultured Tumor-infiltrating Lymphocytes Display Optimal Characteristics for Adoptive Cell Therapy

(2008) Khoi Q. Tran et al.   JOURNAL OF IMMUNOTHERAPY

High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents

(2008) B. Polyak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy

(2007) Ronald J Buckanovich et al.   NATURE MEDICINE