Functional and Proteomic Analysis of Streptococcus pyogenes Virulence Upon Loss of Its Native Cas9 Nuclease

CRISPR-Cas in Streptococcus pyogenes

(2019) Anaïs Le Rhun et al.   RNA Biology

Group A Streptococcus encounters with host macrophages

(2018) J Andrés Valderrama et al.   Future Microbiology

Streptococcus pyogenes CAMP factor promotes bacterial adhesion and invasion in pharyngeal epithelial cells without serum via PI3K/Akt signaling pathway

(2018) Mie Kurosawa et al.   MICROBES AND INFECTION

Variation, Indispensability, and Masking in the M protein

(2018) Partho Ghosh   TRENDS IN MICROBIOLOGY

Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas

(2018) John D. Lapek et al.   Cell Systems

The Involvement of the Cas9 Gene in Virulence of Campylobacter jejuni

(2018) Muhammad A. B. Shabbir et al.   Frontiers in Cellular and Infection Microbiology

Detection of dysregulated protein-association networks by high-throughput proteomics predicts cancer vulnerabilities

(2017) John D Lapek et al.   NATURE BIOTECHNOLOGY

Group A streptococcal M protein activates the NLRP3 inflammasome

(2017) J. Andrés Valderrama et al.   Nature Microbiology

Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones

(2017) Simon Döhrmann et al.   Scientific Reports

The YvqE two-component system controls biofilm formation and acid production inStreptococcus pyogenes

(2016) Masanori Isaka et al.   APMIS

Streptococcus pyogenesadhesion and colonization

(2016) Stephan Brouwer et al.   FEBS LETTERS

Streptococcus pyogenes CAMP factor attenuates phagocytic activity of RAW 264.7 cells

(2016) Mie Kurosawa et al.   MICROBES AND INFECTION

Major bacterial lineages are essentially devoid of CRISPR-Cas viral defence systems

(2016) David Burstein et al.   Nature Communications

Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing

(2015) Christopher N. LaRock et al.   Cell Host & Microbe

An updated evolutionary classification of CRISPR–Cas systems

(2015) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

(2014) Yuyu Niu et al.   CELL

The Classical Lancefield Antigen of Group A Streptococcus Is a Virulence Determinant with Implications for Vaccine Design

(2014) Nina M. van Sorge et al.   Cell Host & Microbe

Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus

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The Role of CRISPR-Cas Systems in Virulence of Pathogenic Bacteria

(2014) R. Louwen et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Adhesin competence repressor (AdcR) from Streptococcus pyogenes controls adaptive responses to zinc limitation and contributes to virulence

(2014) Misu Sanson et al.   NUCLEIC ACIDS RESEARCH

Reassessment of the Listeria monocytogenes pan-genome reveals dynamic integration hotspots and mobile genetic elements as major components of the accessory genome

(2013) Carsten Kuenne et al.   BMC GENOMICS

A CRISPR/Cas system mediates bacterial innate immune evasion and virulence

(2013) Timothy R. Sampson et al.   NATURE

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

(2013) Wenyan Jiang et al.   NATURE BIOTECHNOLOGY

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

The CRISPR Craze

(2013) E. Pennisi   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

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The CRISPR-Associated Gene cas2 of Legionella pneumophila Is Required for Intracellular Infection of Amoebae

(2013) F. F. Gunderson et al.   mBio

A novel significance score for gene selection and ranking

(2012) Yufei Xiao et al.   BIOINFORMATICS

A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain–Barré syndrome

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Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Cysteine proteinase SpeB from Streptococcus pyogenes – a potent modifier of immunologically important host and bacterial proteins

(2011) Daniel C. Nelson et al.   BIOLOGICAL CHEMISTRY

Phenotypic and transcriptional analysis of the osmotic regulator OmpR in Yersinia pestis

(2011) He Gao et al.   BMC MICROBIOLOGY

Peroxide Stimulon and Role of PerR in Group A Streptococcus

(2011) R. Grifantini et al.   JOURNAL OF BACTERIOLOGY

Molecular insight into invasive group A streptococcal disease

(2011) Jason N. Cole et al.   NATURE REVIEWS MICROBIOLOGY

Streptolysin S-like virulence factors: the continuing sagA

(2011) Evelyn M. Molloy et al.   NATURE REVIEWS MICROBIOLOGY

Genetic Switch to Hypervirulence Reduces Colonization Phenotypes of the Globally Disseminated Group AStreptococcusM1T1 Clone

(2010) Andrew Hollands et al.   JOURNAL OF INFECTIOUS DISEASES

Envelope stress is a trigger of CRISPR RNA-mediated DNA silencing in Escherichia coli

(2010) Ritsdeliz Perez-Rodriguez et al.   MOLECULAR MICROBIOLOGY

Streptococcus Adherence and Colonization

(2009) A. H. Nobbs et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The (p)ppGpp synthetase RelA contributes to stress adaptation and virulence in Enterococcus faecalis V583

(2009) X. Yan et al.   MICROBIOLOGY-SGM

The RAST Server: Rapid Annotations using Subsystems Technology

(2008) Ramy K Aziz et al.   BMC GENOMICS

Interaction between Bacteriophage DMS3 and Host CRISPR Region Inhibits Group Behaviors of Pseudomonas aeruginosa

(2008) M. E. Zegans et al.   JOURNAL OF BACTERIOLOGY

A Naturally Occurring Mutation in ropB Suppresses SpeB Expression and Reduces M1T1 Group A Streptococcal Systemic Virulence

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Sortase A localizes to distinct foci on the Streptococcus pyogenes membrane

(2008) A. Raz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA