A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS

Translation control of the immune checkpoint in cancer and its therapeutic targeting

(2019) Yichen Xu et al.   NATURE MEDICINE

Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome

(2019) Simone Pellegrino et al.   NUCLEIC ACIDS RESEARCH

Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates

(2019) Andrea Riba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate-Induced Formation of Ribosomal Decoding Center for Accurate and Rapid Genetic Code Translation

(2018) Michael Y. Pavlov et al.   Annual Review of Biophysics

Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A

(2018) Marcus Fislage et al.   NUCLEIC ACIDS RESEARCH

Development of a stress response therapy targeting aggressive prostate cancer

(2018) Hao G. Nguyen et al.   Science Translational Medicine

Decoding the Function of Expansion Segments in Ribosomes

(2018) Kotaro Fujii et al.   MOLECULAR CELL

tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis

(2018) Julia Flis et al.   Cell Reports

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Miscoding-induced stalling of substrate translocation on the bacterial ribosome

(2017) Jose L. Alejo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Ribosomes Translate Cancer

(2017) Sergey O. Sulima et al.   Cancer Discovery

A Pan-cancer Analysis of the Expression and Clinical Relevance of Small Nucleolar RNAs in Human Cancer

(2017) Jing Gong et al.   Cell Reports

Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes

(2016) Sichen Shao et al.   CELL

Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression

(2016) Hani Goodarzi et al.   CELL

Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale

(2016) Manuel F Juette et al.   NATURE METHODS

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

(2016) Katherine E. Sloan et al.   RNA Biology

Proofreading neutralizes potential error hotspots in genetic code translation by transfer RNAs

(2016) Jingji Zhang et al.   RNA

Ribosome•RelA structures reveal the mechanism of stringent response activation

(2016) Anna B Loveland et al.   eLife

snoRNA U17 Regulates Cellular Cholesterol Trafficking

(2015) Sarah Jinn et al.   Cell Metabolism

Functional Dynamics within the Human Ribosome Regulate the Rate of Active Protein Synthesis

(2015) Angelica Ferguson et al.   MOLECULAR CELL

Codon Bias as a Means to Fine-Tune Gene Expression

(2015) Tessa E.F. Quax et al.   MOLECULAR CELL

Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome

(2015) Xiaoyu Li et al.   Nature Chemical Biology

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation

(2014) C. Pop et al.   Molecular Systems Biology

Measurement of average decoding rates of the 61 sense codons in vivo

(2014) Justin Gardin et al.   eLife

Structural Basis of the Translational Elongation Cycle

(2013) Rebecca M. Voorhees et al.   Annual Review of Biochemistry

Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia

(2013) Domenica Ronchetti et al.   BMC Medical Genomics

p53 Acts as a Safeguard of Translational Control by Regulating Fibrillarin and rRNA Methylation in Cancer

(2013) Virginie Marcel et al.   CANCER CELL

ETS2 Mediated Tumor Suppressive Function and MET Oncogene Inhibition in Human Non-Small Cell Lung Cancer

(2013) M. Kabbout et al.   CLINICAL CANCER RESEARCH

Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

(2013) Z. Kan et al.   GENOME RESEARCH

Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease

(2013) Annika Mehlem et al.   Nature Protocols

H/ACA Small RNA Dysfunctions in Disease Reveal Key Roles for Noncoding RNA Modifications in Hematopoietic Stem Cell Differentiation

(2013) Cristian Bellodi et al.   Cell Reports

Small nucleolar RNA expression profiling identifies potential prognostic markers in peripheral T-cell lymphoma

(2012) W. Valleron et al.   BLOOD

KrasG12D and p53 Mutation Cause Primary Intrahepatic Cholangiocarcinoma

(2012) M. R. O'Dell et al.   CANCER RESEARCH

A new understanding of the decoding principle on the ribosome

(2012) Natalia Demeshkina et al.   NATURE

DPEP1 Inhibits Tumor Cell Invasiveness, Enhances Chemosensitivity and Predicts Clinical Outcome in Pancreatic Ductal Adenocarcinoma

(2012) Geng Zhang et al.   PLoS One

CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer

(2012) Humberto J. Ferreira et al.   RNA Biology

Clinicopathologic and gene expression parameters predict liver cancer prognosis

(2011) Ke Hao et al.   BMC CANCER

Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress

(2011) Carlos I. Michel et al.   Cell Metabolism

rRNA Pseudouridylation Defects Affect Ribosomal Ligand Binding and Translational Fidelity from Yeast to Human Cells

(2011) Karen Jack et al.   MOLECULAR CELL

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Small nucleolar RNA 42 acts as an oncogene in lung tumorigenesis

(2011) Y-P Mei et al.   ONCOGENE

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA

(2011) Nicholas J. Watkins et al.   Wiley Interdisciplinary Reviews-RNA

Steatohepatitic Hepatocellular Carcinoma (SH-HCC)

(2010) Marcela Salomao et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs

(2010) D. D. Jima et al.   BLOOD

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Conformational Sampling of Aminoacyl-tRNA during Selection on the Bacterial Ribosome

(2010) Peter Geggier et al.   JOURNAL OF MOLECULAR BIOLOGY

When ribosomes go bad: diseases of ribosome biogenesis

(2010) Emily F. Freed et al.   Molecular BioSystems

Modeling Oncogenic Signaling in Colon Tumors by Multidirectional Analyses of Microarray Data Directed for Maximization of Analytical Reliability

(2010) Magdalena Skrzypczak et al.   PLoS One

A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae

(2010) E. B. Kramer et al.   RNA

Nucleotide modifications in three functionally important regions of the Saccharomyces cerevisiae ribosome affect translation accuracy

(2009) Agnès Baudin-Baillieu et al.   NUCLEIC ACIDS RESEARCH

Dysregulation of Ribosome Biogenesis and Translational Capacity Is Associated with Tumor Progression of Human Breast Cancer Cells

(2009) Stéphane Belin et al.   PLoS One

Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster

(2008) Trilochan Sahoo et al.   NATURE GENETICS