Measurement of average decoding rates of the 61 sense codons in vivo

Evaluating bias-reducing protocols for RNA sequencing library preparation

(2014) Thomas J Jackson et al.   BMC GENOMICS

Flipping of the Ribosomal A-Site Adenines Provides a Basis for tRNA Selection

(2014) Xiancheng Zeng et al.   JOURNAL OF MOLECULAR BIOLOGY

A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome

(2014) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation

(2014) J. Zhou et al.   SCIENCE

Distinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments

(2014) Liana F Lareau et al.   eLife

The ribosome as a versatile catalyst: reactions at the peptidyl transferase center

(2013) Marina V Rodnina   CURRENT OPINION IN STRUCTURAL BIOLOGY

Translation elongation can control translation initiation on eukaryotic mRNAs

(2013) Dominique Chu et al.   EMBO JOURNAL

eIF5A Promotes Translation of Polyproline Motifs

(2013) Erik Gutierrez et al.   MOLECULAR CELL

Biases in small RNA deep sequencing data

(2013) Carsten A. Raabe et al.   NUCLEIC ACIDS RESEARCH

Effects of the Yeast RNA-Binding Protein Whi3 on the Half-Life and Abundance of CLN3 mRNA and Other Targets

(2013) Ying Cai et al.   PLoS One

Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P

(2013) L. Peil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positively Charged Residues Are the Major Determinants of Ribosomal Velocity

(2013) Catherine A. Charneski et al.   PLOS BIOLOGY

Decoding properties of tRNA leave a detectable signal in codon usage bias

(2012) Alexander C. Roth   BIOINFORMATICS

Mechanisms of SecM-Mediated Stalling in the Ribosome

(2012) James Gumbart et al.   BIOPHYSICAL JOURNAL

Synthetic biology challenges long-held hypotheses in translation, codon bias and transcription

(2012) Anthony C. Forster   Biotechnology Journal

A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress

(2012) Onn Brandman et al.   CELL

Arginine Changes the Conformation of the Arginine Attenuator Peptide Relative to the Ribosome Tunnel

(2012) Cheng Wu et al.   JOURNAL OF MOLECULAR BIOLOGY

The anti-Shine–Dalgarno sequence drives translational pausing and codon choice in bacteria

(2012) Gene-Wei Li et al.   NATURE

A new understanding of the decoding principle on the ribosome

(2012) Natalia Demeshkina et al.   NATURE

EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues

(2012) L. K. Doerfel et al.   SCIENCE

Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches

(2012) S. Ude et al.   SCIENCE

Speeding with control: codon usage, tRNAs, and ribosomes

(2012) Eva Maria Novoa et al.   TRENDS IN GENETICS

Balanced Codon Usage Optimizes Eukaryotic Translational Efficiency

(2012) Wenfeng Qian et al.   PLoS Genetics

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

The ribosomal tunnel as a functional environment for nascent polypeptide folding and translational stalling

(2011) Daniel N Wilson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Nascent Peptide Side Chains Induce Rearrangements in Distinct Locations of the Ribosomal Tunnel

(2011) Jianli Lu et al.   JOURNAL OF MOLECULAR BIOLOGY

Messenger RNA interactions in the decoding center control the rate of translocation

(2011) Prashant K Khade et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Evolutionarily Conserved Mechanism for Controlling the Efficiency of Protein Translation

(2010) Tamir Tuller et al.   CELL

Multimodal RNA-seq using single-strand, double-strand, and CircLigase-based capture yields a refined and extended description of the C. elegans transcriptome

(2010) A. T. Lamm et al.   GENOME RESEARCH

Synonymous but not the same: the causes and consequences of codon bias

(2010) Joshua B. Plotkin et al.   NATURE REVIEWS GENETICS

α-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel

(2010) Shashi Bhushan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

pH-sensitivity of the ribosomal peptidyl transfer reaction dependent on the identity of the A-site aminoacyl-tRNA

(2010) M. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene optimization mechanisms: A multi-gene study reveals a high success rate of full-length human proteins expressed inEscherichia coli

(2010) Barbara Maertens et al.   PROTEIN SCIENCE

Quantification of the yeast transcriptome by single-molecule sequencing

(2009) Doron Lipson et al.   NATURE BIOTECHNOLOGY

A signal-anchor sequence stimulates signal recognition particle binding to ribosomes from inside the exit tunnel

(2009) U. Berndt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Peptidyl-prolyl-tRNA at the ribosomal P-site reacts poorly with puromycin

(2008) Hiroki Muto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mistranslation-Induced Protein Misfolding as a Dominant Constraint on Coding-Sequence Evolution

(2008) D. Allan Drummond et al.   CELL

Modulation of the Rate of Peptidyl Transfer on the Ribosome by the Nature of Substrates

(2008) Ingo Wohlgemuth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant

(2008) Gregor Blaha et al.   JOURNAL OF MOLECULAR BIOLOGY

Electrostatics in the Ribosomal Tunnel Modulate Chain Elongation Rates

(2008) Jianli Lu et al.   JOURNAL OF MOLECULAR BIOLOGY

Slow peptide bond formation by proline and other N-alkylamino acids in translation

(2008) M. Y. Pavlov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Side-chain recognition and gating in the ribosome exit tunnel

(2008) P. M. Petrone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study

(2008) Nicola A. Burgess-Brown et al.   PROTEIN EXPRESSION AND PURIFICATION