Review
Biochemistry & Molecular Biology
Petra Baum, Klaus V. Toyka, Matthias Blueher, Joanna Kosacka, Marcin Nowicki
Summary: The pathogenesis of diabetic neuropathy is complex, with low-grade intraneural inflammation being a common feature. In addition to iron deficiency, obesity and dyslipidemia may also contribute to neuropathy. Anti-inflammatory compounds with different modes of action could potentially be used for treatment or prevention of diabetic neuropathy if further substantiated by human tissue data and intervention studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Endocrinology & Metabolism
Yue Yin, Lina Wang, Ling Zhao, Lin Lin, Xueyong Shen
Summary: 10.6 μm laser moxibustion can relieve pain, improve microcirculation, and alleviate inflammation in DPN rats, possibly via the NF-κB inflammatory pathway.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Immunology
Yanxia Lu, Bao-Peng Liu, Crystal T. Y. Tan, Fang Pan, Anis Larbi, Tze Pin Ng
Summary: The link between pathogen exposure and mental health has been investigated in a study of over 800 participants in the Singapore Longitudinal Ageing Studies. The study found that high pathogen burden is associated with increased prevalence of depressive symptoms and impaired mental health. Certain infections and inflammatory markers were found to mediate this association. These findings highlight the potential impact of pathogens on mental health.
BRAIN BEHAVIOR AND IMMUNITY
(2022)
Article
Endocrinology & Metabolism
Jia-Lin Yuan, Le Sun, Bao-Lin Su, Chuang-Xiong Hong
Summary: This case presents a specific adverse drug reaction of corticosteroids that causes diabetes mellitus and subsequently leads to peripheral neuropathy in an acute onset. Mecobalamin and Acupuncture were employed and steroids were discontinued, 8 months later he recovered part of his strength and sensation.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Mishaela R. Rubin, Ian H. de Boer, Jye-Yu C. Backlund, Valerie Arends, Rose Gubitosi-Klug, Amisha Wallia, Naina Sinha Gregory, Annette Barnie, Andrew J. Burghardt, John M. Lachin, Barbara H. Braffett, Ann Schwartz
Summary: Poor glycemic control is associated with reduced bone formation in T1D patients, while reduced kidney function is associated with increased bone resorption and formation.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Biotechnology & Applied Microbiology
Yijie Duan, Weiyan Ren, Wei Liu, Jianchao Li, Fang Pu, Yih-Kuen Jan
Summary: This study found a significant correlation between tissue hardness and static peak plantar pressure (PPP), and between tissue hardness and dynamic pressure-time integral (PTI) in people with diabetic peripheral neuropathy (DPN). People with DPN in the higher loading group showed significantly greater tissue hardness compared to those without DPN.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Endocrinology & Metabolism
Zhi Yang, Xiaoyang Lou, Jie Zhang, Ronghui Nie, Jiang Liu, Ping Tu, Peng Duan
Summary: DKD and DPN are common complications of T2DM. This study found that when T2DM patients have CKD, DPN is more likely to occur or worsen. Easily detectable urinary markers of renal damage can be used for early prediction of DPN, with increased NAG/Cr being an independent risk factor.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2021)
Article
Biology
Mar Sempere-Bigorra, Ivan Julian-Rochina, Pilar Perez-Ros, Emmanuel Navarro-Flores, Francisco Miguel Martinez-Arnau, Omar Cauli
Summary: Aging and diabetes both contribute to neurological damage, and this study explores the relationships between peripheral sensory system decline and cognitive functions, symptoms of depression, and quality of life in older adults. The findings suggest that superficial sensitivity damage is related to cognitive impairment, while deep sensation alterations are related to depression and poor quality of life, with diabetes further strengthening these relationships.
Article
Medicine, General & Internal
Zhen-Fei Li, Xiao-Li Niu, Ling-Ling Nie, Li-Ping Chen, Cui-Fang Cao, Li Guo
Summary: This study aimed to evaluate the diagnostic efficacy of different tendon reflexes in detecting diabetic peripheral neuropathy. The researchers found that the assessment of tendon reflexes can be proposed as a test for screening diabetic polyneuropathy.
ARCHIVES OF MEDICAL SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Jonathan Enders, Daniel Elliott, Douglas E. Wright
Summary: Diabetic peripheral neuropathy (DPN) is a complication of metabolic syndrome and diabetes, causing sensory changes such as slow nerve conduction, nerve degeneration, loss of sensation, pain, and gait abnormalities. Nonpharmacologic approaches, including dietary interventions and exercise, show promise in treating DPN. These lifestyle interventions have the potential to provide meaningful relief for patients and identify new therapeutic targets.
ANTIOXIDANTS & REDOX SIGNALING
(2023)
Article
Geriatrics & Gerontology
Caitlin W. Hicks, Dan Wang, Natalie Daya, Stephen P. Juraschek, Kunihiro Matsushita, B. Gwen Windham, Elizabeth Selvin
Summary: This study found that peripheral neuropathy (PN) detected by monofilament testing is common in older adults, even in the absence of diabetes. These individuals have an increased risk of falls and fractures. Therefore, screening with monofilament testing may help identify older adults at high risk for falls.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Review
Endocrinology & Metabolism
Dusti R. Jones, Jennifer E. Graham-Engeland
Summary: The research suggests that positive affect may promote health and longevity through stress-buffering mechanisms rather than directly affecting inflammatory markers. Studies using state/aggregated measures of positive affect showed more consistent associations with inflammatory markers.
PSYCHONEUROENDOCRINOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Alan Bapeer Hassan, Ali Hussein Ahmad Al-Dosky
Summary: Clinical studies have shown that there is an association between vitamin D deficiency and painful diabetic peripheral neuropathy (DPN). However, this study found that while vitamin D deficiency was related to painful DPN, there was no significant correlation with inflammatory markers.
Review
Neurosciences
Yifan Cheng, Yinuo Chen, Kezheng Li, Shuwei Liu, Chunyang Pang, Lingfei Gao, Jiali Xie, L. V. Wenjing, Huan Yu, Binbin Deng
Summary: This review aims to summarize the current knowledge on the pathogenesis of DPN, with a focus on the mechanism and application of inflammatory response.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Geriatrics & Gerontology
Betty Manrique-Espinoza, Rosa Palazuelos-Gonzalez, Victoria Pando-Robles, Oscar Rosas-Carrasco, Aaron Salinas-Rodriguez
Summary: This study analyzed the association between tumor necrosis factor-alpha (TNF-alpha), Interleukin-10 (IL-10), C-reactive protein (CRP) and physical performance in a sample of older adults in rural Mexico. The results showed a significant association between higher CRP levels and low physical performance, while IL-10 and TNF-alpha did not show a significant association.
Article
Oncology
Joyita Banerjee, Jata Satapathy, Ashish Dutt Upadhyay, Sada Nand Dwivedi, Prasun Chatterjee, Lalit Kumar, Goura Kishor Rath, Aparajit Ballav Dey
JOURNAL OF GERIATRIC ONCOLOGY
(2019)
Article
Engineering, Biomedical
Daqing Piao, Lara A. Sypniewski, Danielle Dugat, Christian Bailey, Daniel J. Burba, Luis DeTaboada
LASERS IN MEDICAL SCIENCE
(2019)
Article
Orthopedics
Ryan C. Locke, Elisabeth A. Lemmon, Ellen Dudzinski, Sarah C. Kopa, Julianna M. Wayne, Jaclyn M. Soulas, Luis De Taboada, Megan L. Killian
JOURNAL OF ORTHOPAEDIC RESEARCH
(2020)
Article
Geriatrics & Gerontology
Swati Bajpai, Ashish Upadhyay, Hemchand Sati, R. M. Pandey, Prasun Chaterjee, A. B. Dey
CLINICAL INTERVENTIONS IN AGING
(2020)
Letter
Geriatrics & Gerontology
Prasun Chatterjee, Santosh K. Yatnatti
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2020)
Article
Multidisciplinary Sciences
Abhijith Rajaram Rao, Prasun Chatterjee, Meenal Thakral, S. N. Dwivedi, Aparajit Ballav Dey
Article
Neurosciences
Vincenza Spera, Tatiana Sitnikova, Meredith J. Ward, Parya Farzam, Jeremy Hughes, Samuel Gazecki, Eric Bui, Marco Maiello, Luis De Taboada, Michael R. Hamblin, Maria Angela Franceschini, Paolo Cassano
Summary: The study found that transcranial photobiomodulation has a dose-dependent effect on enhancing gamma and beta neuronal activity in the brain, with a widespread increase over frontal-central scalp regions. The results indicate a neuromodulatory effect of transcranial near-infrared light.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Article
Psychology, Clinical
Dan V. Iosifescu, Richard J. Norton, Umit Tural, David Mischoulon, Katherine Collins, Erin McDonald, Luis De Taboada, Simmie Foster, Cristina Cusin, Albert Yeung, Alisabet Clain, David Schoenfeld, Michael R. Hamblin, Paolo Cassano
Summary: This double-blind, sham-controlled study tested the efficacy of low-dose transcranial photobiomodulation (t-PBM) in individuals with major depressive disorder (MDD). The results showed that low-dose t-PBM did not significantly reduce depression severity. This study provides evidence for determining the optimal dosage of t-PBM for MDD treatment.
JOURNAL OF CLINICAL PSYCHIATRY
(2022)
Review
Surgery
Lisa A. Miller, Debbie (Gross) Torraca, Luis De Taboada
PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY
(2020)
Review
Surgery
Farzad Salehpour, Paolo Cassano, Naser Rouhi, Michael R. Hamblin, Luis De Taboada, Fereshteh Farajdokht, Javad Mahmoudi
PHOTOBIOMODULATION PHOTOMEDICINE AND LASER SURGERY
(2019)
Proceedings Paper
Biophysics
Daqing Piao, Lara A. Sypniewski, Danielle Dugat, Christian Bailey, Luis DeTaboada, Daniel J. Burba
MECHANISMS OF PHOTOBIOMODULATION THERAPY XIV
(2019)
Article
Demography
Joyita Banerjee, Urvashi Jain, Pranali Khobragade, Bas Weerman, Peifeng Hu, Sandy Chien, Sharmistha Dey, Prasun Chatterjee, Judith Saxton, Brenton Keller, Eileen Crimmins, Arthur Toga, Arvind Jain, G. S. Shanthi, Ravi Kurup, Aruna Raman, Sankha Shubhra Chakrabarti, Mathew Varghese, John P. John, Himanshu Joshi, Parvaiz Koul, Debabrata Goswami, Arunanshu Talukdar, Rashmi Ranjan Mohanty, Y. Sathyanarayana Raju Yadati, Mekala Padmaja, Lalit Sankhe, Sarang Pedgaonkar, Perianayagam Arokiasamy, David E. Bloom, Kenneth Langa, Jorge Jovicich, Aparajit Ballav Dey, Jinkook Lee, Indrajeet Singh Gambhir, Chhaya Rajguru
BIODEMOGRAPHY AND SOCIAL BIOLOGY
(2019)
Article
Public, Environmental & Occupational Health
Prasun Chatterjee, George W. Rebok, Sada N. Dwivedi, Deepa A. Kumar, Ruchika Madan, Aparajit B. Dey
INDIAN JOURNAL OF PUBLIC HEALTH
(2019)