Article
Biotechnology & Applied Microbiology
Li Liu, Yue Chen, Shiqin Yu, Jian Chen, Jingwen Zhou
Summary: In this study, key D-sorbitol dehydrogenases in Gluconobacter oxydans WSH-003 were identified through gene knockout. By knocking out dehydrogenase genes, the production of L-sorbose was significantly enhanced. G. oxydans-30 showed reduced by-product formation, while G. oxydans MD-16 achieved the highest conversion ratio. The systematic engineering of dehydrogenases greatly improved L-sorbose production.
SYNTHETIC AND SYSTEMS BIOTECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Ankita Tripathi, Kshatresh Dutta Dubey
Summary: This study demonstrates a method to enhance promiscuity, called allostery-driven promiscuity, using molecular dynamics simulations and hybrid QM/MM calculations. By studying the AEE enzyme, the authors show that a single site mutation can induce conformational changes in the capping loop, allowing recognition of different substrates for different functions.
CHEMISTRY-AN ASIAN JOURNAL
(2022)
Article
Chemistry, Medicinal
Bharath Raghavan, Florian K. Schackert, Andrea Levy, Sophia K. Johnson, Emiliano Ippoliti, Davide Mandelli, Jogvan Magnus Haugaard Olsen, Ursula Rothlisberger, Paolo Carloni
Summary: MiMiC is a flexible and scalable multiscale modeling framework that combines quantum mechanics (QM) and molecular mechanics (MM) codes. The paragraph introduces MiMiCPy, a user-friendly tool written in Python 3 that automates the preparation of MiMiC input files. It also highlights the modular structure of MiMiCPy, allowing for easy extensions to new program formats.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
(2023)
Article
Biotechnology & Applied Microbiology
Yue Chen, Li Liu, Shiqin Yu, Jianghua Li, Jingwen Zhou, Jian Chen
Summary: The acetic acid bacterium Gluconobacter oxydans is widely used in industrial production due to its unique incomplete oxidation process, with 2-keto-L-gulonic acid (2-KLG) being one of the compounds produced. Promoters play a crucial role in controlling gene expression, and in this study, the low activity of SDH in G. oxydans was addressed by enhancing SDH expression using newly identified promoters. The study identified several strong promoters that significantly increased the yield of 2-KLG in G. oxydans, providing new tools for metabolic engineering in the production of high-value products.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Yuzhuang Fu, Fangfang Fan, Binju Wang, Zexing Cao
Summary: Enzymatic degradation of pesticides paraoxon (PON) and parathion (PIN) by phosphotriesterase (PTE) has been studied using QM/MM calculations and MD simulations. The results reveal that the hydrolysis reactions are driven by nucleophilic attack and the rate-limiting step is the two-step hydrolytic process.
CHEMISTRY-AN ASIAN JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Yue Chen, Dong Li, Xiaoyu Shan, Jingwen Zhou, Jian Chen
Summary: In this study, the sorbose dehydrogenase of Gluconobacter oxydans WSH-004 was identified as a sorbose oxidase (SOX). The study also found that H2O2 inhibited the activity of SOX and identified phenazine methosulfate (PMS) as the best electron acceptor for SOX. Furthermore, the enzymatic catalysis of SOX and SNDH was conducted in vitro to produce 2-KLG from L-sorbose.
PROCESS BIOCHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Shunya Suenaga, Yu Takano, Toru Saito
Summary: A quantum mechanics/molecular mechanics molecular dynamics (QM/MM MD) study was conducted on three representative competitive inhibitors of urease. The study found that N-(n-butyl)phosphorictriamide (NBPTO) exhibited the highest inhibitory activity and the lowest IC50 value, followed by acetohydroxamic acid (AHA) and hydroxyurea (HU). The structural and thermodynamical properties of the inhibitors were found to be correlated with their inhibition efficiency.
Article
Agricultural Engineering
Dong Li, Xinglong Wang, Zhijie Qin, Shiqin Yu, Jian Chen, Jingwen Zhou
Summary: Mutants of L-sorbose dehydrogenase (SDH) were designed to enhance the production of 2-keto-L-gulonic acid (2-KLG). A combination of SDH engineering and fermentation optimization effectively increased the production of 2-KLG.
BIORESOURCE TECHNOLOGY
(2023)
Article
Chemistry, Physical
Fan Li, Cai-Yun Wang, Meng-Yue Zhang, Yi-Xuan Zhang
Summary: This study investigated eight L-sorbose dehydrogenases in K. vulgare SPU B805 and K. robustum SPU_B003, revealing their crucial roles in 2-KGA synthesis and proposing a novel whole-cell recycling catalysis system to achieve high productivity.
MOLECULAR CATALYSIS
(2022)
Article
Chemistry, Physical
Qiang Cui, Tanmoy Pal, Luke Xie
Summary: This article discusses the challenges and issues in QM/MM simulations, emphasizing the importance of these issues for applications in biomolecular systems. Despite its limited scope, the hope is to stimulate further developments in the field of QM/MM simulation methods.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Biochemistry & Molecular Biology
Francisco Andres Peralta, J. Pablo Huidobro-Toro, Raul Mera-Adasme
Summary: QM/MM molecular dynamic simulations were used to study the allosteric modulator role of Zn(II) on P2X4R, revealing insights into the nature of Zn(II) modulation and the effects of mutations, potentially explaining elusive modulation mechanisms in other extracellular or membrane proteins.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Phujinn Honorio, Supawadee Sainimnuan, Supa Hannongbua, Patchreenart Saparpakorn
Summary: The research discovered that protoberberine alkaloids isolated from natural resources are potent inhibitors of acetylcholinesterase (AChE) and have the potential to reduce symptoms of Alzheimer's disease. The key interactions of palmatine and berberine with AChE were identified as 7C-7C interactions with specific amino acids and H-bond interactions. In contrast, cyclanoline showed a different binding mode and preference for a deeper site within AChE.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Article
Chemistry, Physical
Alessandra G. Ritacca, Anna Rovaletti, Giorgio Moro, Ugo Cosentino, Ulf Ryde, Emilia Sicilia, Claudio Greco
Summary: This study proposes a novel mechanism for the oxidation of CO into CO2 by Mo/Cu CO dehydrogenase, and explores the role of a stable thiocarbonate intermediate. The findings suggest that the thiocarbonate does not interfere with the CO oxidation catalytic cycle, highlighting the importance of environmental effects in computational modeling.
Article
Biochemistry & Molecular Biology
Raul Alvarado, Gustavo Cardenas, Juan J. Nogueira, Nicolas Ramos-Berdullas, Marcos Mandado
Summary: This study simulated the permeation of dioxin-like pollutants through lipid membranes using CMD and umbrella sampling. The results showed that TCDD and TCDF reached energy minima at distances of 8 angstrom and 9.5 angstrom from the centre of the membrane, respectively. The interactions between the molecules and the lipid membrane were mainly governed by dispersion forces, independent of the toxicity of the molecules.
Article
Chemistry, Physical
Prashant Singh, Durgesh Kumar, Shweta Pal, Kamlesh Kumari, Indra Bahadur
Summary: The importance of different amino acids in human immunity, particularly their potential role in inhibiting the main protease of SARS-CoV-2, has been explored. Arginine has been found to have promising inhibitory effects on the main protease of SARS-CoV-2. Further studies are needed to investigate the potential of arginine in boosting immunity.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Review
Biochemistry & Molecular Biology
Chandrabose Selvaraj, Ishwar Chandra, Sanjeev Kumar Singh
Summary: The global spread of COVID-19 has highlighted the significance of pharmaceutical drug development, with artificial intelligence and machine learning methods playing a crucial role in enhancing the success rate of new drug development.
MOLECULAR DIVERSITY
(2022)
Editorial Material
Pharmacology & Pharmacy
Sugunadevi Sakkiah, Brijesh Kumar Singh, Keun Woo Lee, Chandrabose Selvaraj
FRONTIERS IN PHARMACOLOGY
(2022)
Editorial Material
Biochemistry & Molecular Biology
Chandrabose Selvaraj, Sugunadevi Sakkiah, Dhurvas Chandrasekaran Dinesh
CURRENT MOLECULAR PHARMACOLOGY
(2022)
Review
Nutrition & Dietetics
JinJin Pei, Vidhya Rekha Umapathy, Srinivasan Vengadassalapathy, Shazia Fathima Jaffer Hussain, Selvaraj Jayaraman, Vishnu Priya Veeraraghavan, Chella Perumal Palanisamy, Krishnasamy Gopinath, Ponnulakshmi Rajagopal
Summary: Pearl millet can be used to prepare food products for diabetes management and has many health benefits.
Article
Green & Sustainable Science & Technology
Subramanian Radhesh Krishnan, Pandiyan Muthuramalingam, Arumugam Mohana Priya, Mani Iyer Prasanth, Krishnasamy Gopinath, Chakravarthi Mohan, Karthikeyan Muthusamy, Krishnaswamy Balamurugan, Aditya Kumar Gupta, Manikandan Ramesh
Summary: This study demonstrates that overexpression of OsiSAP8 driven by Port Ubi2.3 from Porteresia coarctata confers drought and salinity stress tolerance in transgenic rice. The transgenic line IR36 showed enhanced tolerance to water withhold stress and superior physiological parameters compared to the wild type and IR64. This is the first study using the novel ubiquitin promoter Port Ubi2.3 to generate drought and salinity stress-tolerant transgenic rice.
Article
Biotechnology & Applied Microbiology
Anuraj Nayarisseri, Anushka Bhrdwaj, Arshiya Khan, Khushboo Sharma, Uzma Shaheen, Chandrabose Selvaraj, Mohammad Aqueel Khan, Rajaram Abhirami, Muthuraja Arun Pravin, Gurunathan Rubha Shri, Dhanjay Raje, Sanjeev Kumar Singh
Summary: Gene expression varies due to intrinsic stochasticity and external perturbations. Co-regulation and co-expression guide the transcription process. Technical improvements have made it easier to analyze complex proteomes and biological switches, with microarray technology serving as a viable platform. This research enables the clustering of co-expressed and co-regulated genes using microarray.
BRIEFINGS IN FUNCTIONAL GENOMICS
(2023)
Article
Biochemistry & Molecular Biology
Anushka Bhrdwaj, Mohnad Abdalla, Aditi Pande, Maddala Madhavi, Ishita Chopra, Lovely Soni, Natchimuthu Vijayakumar, Umesh Panwar, Mohd. Aqueel Khan, Leena Prajapati, Deepika Gujrati, Pranoti Belapurkar, Sarah Albogami, Tajamul Hussain, Chandrabose Selvaraj, Anuraj Nayarisseri, Sanjeev Kumar Singh
Summary: This article investigates the biomarkers of glioblastoma to predict the patient's condition and select treatment options. Through virtual screening, a chemical compound with higher affinity is discovered, potentially serving as a promising therapy for this disease.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Medicine, Research & Experimental
Sana Kari, Akshaya Murugesan, Ramesh Thiyagarajan, Srivatsan Kidambi, Jamoliddin Razzokov, Chandrabose Selvaraj, Meenakshisundaram Kandhavelu, Parthiban Marimuthu
Summary: Glioblastoma Multiforme (GBM) is the most aggressive brain tumor in adults, with a median survival rate of less than 15 months. The GBM cells develop resistance to chemo-and radiotherapy, indicating the need for novel preventative measures. The study identified potential GPR17 modulators using virtual screening and molecular dynamics simulations, and validated their effectiveness in inhibiting GBM cell accumulation. This research provides new insights into the development of targeted therapies for deadly diseases.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Biotechnology & Applied Microbiology
Chandrabose Selvaraj, Dhurvas Chandrasekaran Dinesh, Emilia Maria Pedone, Abdulaziz S. Alothaim, Rajendran Vijayakumar, Ondippili Rudhra, Sanjeev Kumar Singh
Summary: This study provides detailed structural insights into SARS-CoV-2 ORF8 interchain disulfide bond disruptors through computational mutational studies and identifies potential drug candidates for disrupting the formation of the dimer by targeting the interchain disulfide bridge. These compounds may inhibit the potential functional role of ORF8 in host immune evasion and virulence pathogenicity.
BRIEFINGS IN FUNCTIONAL GENOMICS
(2023)
Article
Biochemistry & Molecular Biology
Devaraj Ezhilarasan, Karthik Shree Harini, Munusamy Karthick, Chandrabose Selvaraj
Summary: This study evaluated the protective role of ethyl gallate (EG) against acetaminophen (APAP)-induced acute liver injury. The results showed that EG has antioxidative, free radical scavenging, and anti-inflammatory potentials, which can effectively alleviate liver damage caused by APAP.
CHEMICAL BIOLOGY & DRUG DESIGN
(2023)
Review
Cell Biology
Majid Ghasemian, Hossein Babaahmadi-Rezaei, Azam Khedri, Chandrabose Selvaraj
Summary: SAMMSON is an upregulated lncRNA that plays an oncogenic role in several tumors and is closely associated with multiple pathways and clinical features. It has the potential to serve as a diagnostic and prognostic biomarker and a therapeutic target in various cancers. Additionally, SAMMSON plays a significant role in regulating epigenetic processes by influencing histone protein or DNA methylation status.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2023)
Article
Biochemical Research Methods
Periyasamy Natarajan Shiammala, Navaneetha Krishna Bose Duraimutharasan, Baskaralingam Vaseeharan, Abdulaziz S. Alothaim, Esam S. Al-Malki, Babu Snekaa, Sher Zaman Safi, Sanjeev Kumar Singh, Devadasan Velmurugan, Chandrabose Selvaraj
Summary: Artificial intelligence, particularly deep learning, has the potential to accelerate and improve the process of drug discovery and development by identifying new drug targets, designing new molecules, and predicting drug efficacy and safety. It can screen millions of compounds in a short period of time, significantly reducing the time and effort required compared to traditional methods. AI is also widely used in optimizing pharmaceutical processes and ensuring quality control.
Article
Microbiology
Ashwini Ashok Bedekar, Anshu Deewan, Sujit S. Jagtap, David A. Parker, Ping Liu, Roderick I. Mackie, Christopher V. Rao
Summary: This study investigates the response of the methane-oxidizing bacterium M. capsulatus Bath to nitrogen source and temperature. It reveals complex transcriptional changes, differential expression of nitrogen metabolism pathways, and alterations in intracellular metabolites under different conditions. The findings enhance our understanding of microbial adaptation strategies and have potential applications in biotechnology and environmental contexts.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Environmental Sciences
Saif Ali Ali Sultan, Fawad Ahmed Khan, Abdul Wahab, Batool Fatima, Hira Khalid, Ali Bahader, Sher Zaman Safi, Chandrabose Selvaraj, Abid Ali, Suliman Yousef Alomar, Muhammad Imran
Summary: The use of inexpensive aluminum cookware without knowledge of its potential health risks is a growing concern. Leaching of toxic metals into food from cookware poses a serious health risk to individuals.
Article
Microbiology
Sujit Sadashiv Jagtap, Jing-Jing Liu, Hanna E. Walukiewicz, Jasmyn Pangilinan, Anna Lipzen, Steven Ahrendt, Maxim Koriabine, Kelly Cobaugh, Asaf Salamov, Yuko Yoshinaga, Vivian Ng, Chris Daum, Igor V. Grigoriev, Patricia J. Slininger, Bruce S. Dien, Yong-Su Jin, Christopher V. Rao
Summary: This study presents the annotated genome sequence of Lipomyces tetrasporous NRRL Y-64009 and explores its potential as a platform organism for the production of lipids and lipid-based bioproducts.
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2023)
Article
Biotechnology & Applied Microbiology
Yiran Qu, Innocent Bekard, Ben Hunt, Jamie Black, Louis Fabri, Sally L. Gras, Sandra. E. Kentish
Summary: This study compares the performance of a nanofiber device and a resin column for antibody capture. The nanofiber device has a larger housing volume and lower binding capacity, but comparable eluate purity to the resin column. It shows high stability, can be used for multiple cycles, and maintains consistent eluate quality when scaled up. The use of a single nanofiber device can significantly reduce costs compared to a resin column, especially when the number of batches is limited.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Brandon Moore, Christos Georgakis, Chris Antoniou, Sarwat Khattak
Summary: Fed-batch cell culture processes are commonly used in biomanufacturing due to their simplicity and applicability in cGMP environments. However, the challenge lies in the changing physiochemical conditions within the bioreactor as the cell density changes. Traditional response surface models (RSMs) are commonly used for optimization but are limited by their use of time-invariant factors. Dynamic RSM (DRSM) models can predict the time-dependent impact of process inputs, allowing for optimization of process operations that change over time.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Lin Li, Yunfan Bai, Chuhua Qi, Yile Du, Xiaoxiao Ma, Yutong Li, Pingping Wu, Shuangli Chen, Sijing Zhang
Summary: A succinic anhydride-modified apple pomace (SAMAP) was synthesized to address environmental issues caused by the accumulation of apple pomace and effectively treat heavy metal ions. SAMAP exhibited high adsorption capacity for Cu(II) and Pb(II), suggesting its potential application in wastewater treatment.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Peter Satzer
Summary: Water for injection (WFI) production in the biopharmaceutical industry consumes excessive amounts of water and energy. Recycling buffers can potentially save up to 90% of resources, but achieving the full theoretical potential is impossible when a risk-aware design is used. Universal risk-based assessment is important for regulatory authorities to consider the implementation of such a strategy.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Gaoya Sun, Lingkai Jin, Guangxue Wang, Xiaoge Wang, Jin Huang
Summary: In this study, heterologous expression and homologous overexpression of ABC transporter proteins AatA and MdlB were found to improve butyric acid production in C. tyrobutyricum. The overexpression of these proteins upregulated the expression levels of key enzymes in the acetate synthesis pathway and promoted the synthesis and secretion of acetic acid. Additionally, the increase in ATPase activity facilitated sugar utilization, induced extracellular secretion of acetate, and shortened fermentation periods.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Taiki Okamura, Rina Aritomi, Takuya Matsumoto, Ryosuke Yamada, Hidehiko Hirakawa, Hiroyasu Ogino
Summary: In this study, proline was introduced to improve the stability of putidaredoxin reductase (PdR) in the Pseudomonas putida cytochrome P450 system. It was found that PdR_T221P had a longer half-life at high temperatures compared to wild-type PdR, but a shorter half-life in the presence of methanol. Molecular dynamics simulations supported these findings.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Yuying Hu, Xiaofan Wang, Shihao Zhang, Zimu Liu, Tengfang Hu, Xin Wang, Xiaoming Peng, Hongling Dai, Jing Wu, Fengping Hu
Summary: This study investigates the effect of iron-carbon micro-electrolysis (ICME) materials on high-solid anaerobic digestion (HSAD). The results show that ICME materials promote methane production in HSAD by increasing the attachment area of microorganisms and facilitating symbiotic metabolism of certain bacterial species. This study provides new insights into microbial mechanisms and enhances our understanding of ICME material enhancement in HSAD.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Jibao Liu, Yufeng Xu, Yuansong Wei
Summary: This study investigated the role of sludge rheology in anaerobic digestion (AD) and found that rheological properties increased with the increase of solid content, resulting in a negative effect on methane production. An extended ADM1 model revealed that enhanced sludge rheological properties increased mass diffusion resistance and reduced uptake rate of acetate.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Xiaoyan Liu, Zongze Chen, Dewen Kong, Xinying Zhang, Chuanhua Wang, Yongqi Wang
Summary: This study explored the role of intracellular and extracellular enzymes of Acinetobacter baumannii and Talaromyces sp. in the degradation of crude oil. The extracellular enzymes of Talaromyces sp. were more effective in degrading n-alkanes, while those of Acinetobacter baumannii had a better effect on aromatic hydrocarbons. The degradation enzyme systems of both bacteria and fungi complemented each other, improving the overall degradation ability.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Jing Dong, Lingli Xu, Yuxiang Liu, Li Ren, Ke Yuan
Summary: The utilization of biochar-immobilized microorganisms is an effective method for eliminating phenol from water. The high susceptibility of bacteria to environmental factors is a challenge for practical implementation. In this study, biochar was used to reduce microbial susceptibility and enhance phenol removal. The addition of biochar altered the dominant species of phenol-degrading bacteria and response surface analysis indicated the significant influence of biochar pyrolysis temperature and experimental temperature on phenol removal rate.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Zibin Pan, Mengying Liu, Zuliang Chen
Summary: This study successfully removed metalloids and heavy metals from acid mine drainage (AMD) using bio-synthesized Fe/Cu nanoparticles (Fe/Cu NPs). The Fe/Cu NPs showed high removal capacities and the presence of organic substances contributed to their stability.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Guangbing Liu, Han Zhang, Jincan Huang, Lu Zhang, Teng Zhang, Xuemin Yu, Weijing Liu, Chunkai Huang
Summary: This study investigated the effect of Fenton pre-treatment on the treatment efficiency of printing and dyeing wastewater (PDW) using two anaerobic/aerobic-membrane bioreactors (A/O-MBRs). The results showed that Fenton pre-treatment significantly improved the removal efficiency of COD and AOX in PDW, and reduced membrane fouling. The Shannon indices and metagenomics analysis indicated that the microbial diversity in anaerobic flocs was higher than that in aerobic flocs, and EC3.1.1.45 and pcaI were identified as key functional genes.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Lidia Borgosz, Duygu Dikicioglu
Summary: The Industrial Internet of Things (IIoT) is a system that connects devices and provides real-time insight into industrial processes. However, the complexity and regulatory requirements of the biomanufacturing sector make it challenging to implement IIoT. There is a need for universal solutions to overcome this challenge and advance the field of biomanufacturing.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Yajie Li, Weikang Kong, Yuyao Zhang, Huarui Zhou, Hongbo Liu, Salma Tabassum
Summary: In this study, the iron-carbon multi-micro electric field coupling anaerobic co-digestion technique was used to treat coal gasification wastewater (CGW). The experimental results showed that under optimal operating conditions, this technique can significantly reduce the toxicity of the wastewater and achieve high removal efficiencies. Additionally, the analysis of microbial communities revealed that the coupling system promotes direct interspecies electron transfer.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Aparecido Nivaldo Modenes, Debora Gozzi Fernandes, Daniela Estelita Goes Trigueros, Matheus Guilherme Amador, Fernando Rodolfo Espinoza-Quinones, Taysa de Souza Braniz, Adilson Ricken Schuelter, Glacy Jaqueline da Silva, Lucimar Pereira Bonett
Summary: This study aimed to systematically remove organic pollutants from raw dairy wastewater with high concentrations of COD, TOC, and TN using Poterioochromonas malhamensis algae strains. The results showed that the biomass yield rate using FP-PBRs was 10% higher than tubular PBRs, and the organic pollution in wastewater was significantly reduced with a decrease of about 98% in COD, 95% in TN, and 92% in TOC.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
