The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors

The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors

(2018) Huan Lian et al.   IMMUNITY

Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5

(2017) Ming-Ming Hu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA

(2017) Wei-Wei Luo et al.   PLoS Pathogens

A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation

(2016) Jun Zhao et al.   Cell Host & Microbe

iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING

(2016) Wei-Wei Luo et al.   NATURE IMMUNOLOGY

Krüppel-like factor 4 negatively regulates cellular antiviral immune response

(2014) Wei-Wei Luo et al.   Cellular & Molecular Immunology

USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase

(2014) Yihui Fan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRIM13 Is a Negative Regulator of MDA5-Mediated Type I Interferon Production

(2014) K. Narayan et al.   JOURNAL OF VIROLOGY

Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I-mediated antiviral innate immunity

(2014) K. Kuniyoshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ubiquitin-Specific Protease USP15 Promotes RIG-I-Mediated Antiviral Signaling by Deubiquitylating TRIM25

(2014) E.-K. Pauli et al.   Science Signaling

Antiviral innate immunity and stress granule responses

(2014) Koji Onomoto et al.   TRENDS IN IMMUNOLOGY

TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination

(2014) J. Yan et al.   Journal of Molecular Cell Biology

Cytoplasmic RNA Granules and Viral Infection

(2014) Wei-Chih Tsai et al.   Annual Review of Virology

USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors

(2013) Jun Cui et al.   CELL RESEARCH

Dephosphorylation of the RNA Sensors RIG-I and MDA5 by the Phosphatase PP1 Is Essential for Innate Immune Signaling

(2013) Effi Wies et al.   IMMUNITY

Toll-Like Receptors in Antiviral Innate Immunity

(2013) Sandra N. Lester et al.   JOURNAL OF MOLECULAR BIOLOGY

USP4 Positively Regulates RIG-I-Mediated Antiviral Response through Deubiquitination and Stabilization of RIG-I

(2013) L. Wang et al.   JOURNAL OF VIROLOGY

Small non-coding RNAs encoded within the herpes simplex virus type 1 latency associated transcript (LAT) cooperate with the retinoic acid inducible gene I (RIG-I) to induce beta-interferon promoter activity and promote cell survival

(2013) Leticia Frizzo da Silva et al.   VIRUS RESEARCH

RAVER1 is a coactivator of MDA5-mediated cellular antiviral response

(2013) He Chen et al.   Journal of Molecular Cell Biology

A Distinct Role of Riplet-Mediated K63-Linked Polyubiquitination of the RIG-I Repressor Domain in Human Antiviral Innate Immune Responses

(2013) Hiroyuki Oshiumi et al.   PLoS Pathogens

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

(2013) Siqi Liu et al.   eLife

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

Carcinoembryonic antigen (CEA) and its receptor hnRNP M are mediators of metastasis and the inflammatory response in the liver

(2011) Peter Thomas et al.   CLINICAL & EXPERIMENTAL METASTASIS

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Functional diversity of the hnRNPs: past, present and perspectives

(2010) Siew Ping Han et al.   BIOCHEMICAL JOURNAL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Phosphorylation of RIG-I by Casein Kinase II Inhibits Its Antiviral Response

(2010) Z. Sun et al.   JOURNAL OF VIROLOGY

The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

(2010) Cheng Lu et al.   STRUCTURE

hnRNP M interacts with PSF and p54nrb and co-localizes within defined nuclear structures

(2009) Marija Marko et al.   EXPERIMENTAL CELL RESEARCH

RNA recognition and signal transduction by RIG-I-like receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNOLOGICAL REVIEWS

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Herpes simplex virus infection is sensed by both Toll-like receptors and retinoic acid-inducible gene- like receptors, which synergize to induce type I interferon production

(2008) S. B. Rasmussen et al.   JOURNAL OF GENERAL VIROLOGY

Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses

(2008) Kiyohiro Takahasi et al.   MOLECULAR CELL