Mechanical properties of tubulin intra- and inter-dimer interfaces and their implications for microtubule dynamic instability

Long-range, through-lattice coupling improves predictions of microtubule catastrophe

(2019) Tae Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments

(2018) J. Richard McIntosh et al.   JOURNAL OF CELL BIOLOGY

Effect of Nucleotide State on the Protofilament Conformation of Tubulin Octamers

(2018) Anjela Manandhar et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The role of tubulin–tubulin lattice contacts in the mechanism of microtubule dynamic instability

(2018) Szymon W. Manka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Separating the effects of nucleotide and EB binding on microtubule structure

(2018) Rui Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of tubulin–tubulin lattice contacts in the mechanism of microtubule dynamic instability

(2018) Szymon W. Manka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit

(2018) Maxim Igaev et al.   eLife

Microtubule architecture in vitro and in cells revealed by cryo-electron tomography

(2018) Joseph Atherton et al.   Acta Crystallographica Section D-Structural Biology

Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin

(2017) Weiyi Wang et al.   Nature Communications

Dowser++, a new method of hydrating protein structures

(2016) A. Morozenko et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Molecular and Mechanical Causes of Microtubule Catastrophe and Aging

(2015) Pavel Zakharov et al.   BIOPHYSICAL JOURNAL

Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins

(2015) Rui Zhang et al.   CELL

Detailed Per-residue Energetic Analysis Explains the Driving Force for Microtubule Disassembly

(2015) Ahmed T. Ayoub et al.   PLoS Computational Biology

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

(2014) Gregory M. Alushin et al.   CELL

The contribution of αβ-tubulin curvature to microtubule dynamics

(2014) Gary J. Brouhard et al.   JOURNAL OF CELL BIOLOGY

The Free Energy Profile of Tubulin Straight-Bent Conformational Changes, with Implications for Microtubule Assembly and Drug Discovery

(2014) Lili X. Peng et al.   PLoS Computational Biology

Nucleotide-Dependent Lateral and Longitudinal Interactions in Microtubules

(2013) Andrea Grafmüller et al.   JOURNAL OF MOLECULAR BIOLOGY

Relating nucleotide-dependent conformational changes in free tubulin dimers to tubulin assembly

(2012) Kathiresan Natarajan et al.   BIOPOLYMERS

A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end

(2012) Ludovic Pecqueur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A TOG:  -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase

(2012) P. Ayaz et al.   SCIENCE

ProDy: Protein Dynamics Inferred from Theory and Experiments

(2011) A. Bakan et al.   BIOINFORMATICS

PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions

(2011) Mats H. M. Olsson et al.   Journal of Chemical Theory and Computation

The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin

(2011) Agata Nawrotek et al.   JOURNAL OF MOLECULAR BIOLOGY

The mechanisms of microtubule catastrophe and rescue: implications from analysis of a dimer-scale computational model

(2011) Gennady Margolin et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular dynamics modeling of tubulin C-terminal tail interactions with the microtubule surface

(2011) Holly Freedman et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Intrinsic Bending of Microtubule Protofilaments

(2011) Andrea Grafmüller et al.   STRUCTURE

Anisotropic Elastic Network Modeling of Entire Microtubules

(2010) Marco A. Deriu et al.   BIOPHYSICAL JOURNAL

Tubulin depolymerization may be an ancient biological motor

(2010) J. R. McIntosh et al.   JOURNAL OF CELL SCIENCE

FtsZ in Bacterial Cytokinesis: Cytoskeleton and Force Generator All in One

(2010) H. P. Erickson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structural Mass Spectrometry of the αβ-Tubulin Dimer Supports a Revised Model of Microtubule Assembly

(2009) Melissa J. Bennett et al.   BIOCHEMISTRY

The intrinsic dynamics of enzymes plays a dominant role in determining the structural changes induced upon inhibitor binding

(2009) A. Bakan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Multiscale Parameterization of Heterogeneous Elastic Network Models of Proteins

(2008) Edward Lyman et al.   BIOPHYSICAL JOURNAL

Intrinsic Bending and Structural Rearrangement of Tubulin Dimer: Molecular Dynamics Simulations and Coarse-Grained Analysis

(2008) Yeshitila Gebremichael et al.   BIOPHYSICAL JOURNAL

The lattice as allosteric effector: Structural studies of   - and  -tubulin clarify the role of GTP in microtubule assembly

(2008) L. M. Rice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA