Article
Agriculture, Multidisciplinary
Xueyan Cui, A. M. Abd El-Aty, Chan Zhang, Lingyuan Xu, Haijin Liu, Huiyan Jia, Yuanshang Wang, Zhen Cao, J-Pablo Salvador, Yongxin She, Fen Jin, Jing Wang, Maojun Jin, Bruce D. Hammock
Summary: A bio-barcode immunoassay based on ddPCR was developed to quantify three pesticides in fruits and vegetables, with low detection limits, good recovery rates, and correlations. The study provides insights into the determination of organophosphate pesticides and paves the way for high-throughput detection of other small molecules.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Pharmacology & Pharmacy
Lingyuan Xu, Xiuyuan Zhang, A. M. Abd El-Aty, Yuanshang Wang, Zhen Cao, Huiyan Jia, J. -Pablo Salvador, Ahmet Hacimuftuoglu, Xueyan Cui, Yudan Zhang, Kun Wang, Yongxin She, Fen Jin, Lufei Zheng, Baima Pujia, Jing Wang, Maojun Jin, Bruce D. Hammock
Summary: A highly sensitive fluorescence anti-quenching multi-residue bio-barcode immunoassay has been developed to detect organophosphate pesticides in fruits and vegetables. The method is stable, reliable, and able to detect low residual levels of organophosphate pesticides in agricultural products.
JOURNAL OF PHARMACEUTICAL ANALYSIS
(2022)
Article
Biotechnology & Applied Microbiology
Nayab Fatima, Ugur Akcan, Mehmet Kaya, Radka Gromnicova, Jane Loughlin, Basil Sharrack, David Male
Summary: The aim of the study was to investigate the effect of DNA cargo on tissue distribution of gold glyconanoparticles, and the results showed that the addition of DNA changed the localization of the nanoparticles in liver hepatocytes and splenic macrophages, but not in heart, lung, or brain. DNA increased the size and added a strong negative charge to the nanoparticles, which significantly affected tissue distribution.
Article
Spectroscopy
Qin Ouyang, Yongcun Yang, Shujat Ali, Li Wang, Huanhuan Li, Quansheng Chen
Summary: The study developed a rapid, sensitive, and specific aptasensor based on FRET for detecting Staphylococcus aureus in food. Under optimized conditions, there was a significant linear correlation between fluorescence intensity and S. aureus concentration, demonstrating high detection sensitivity and accuracy.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Multidisciplinary
Maurice Retout, Bryan Gosselin, Amina Adrovic, Pascale Blond, Ivan Jabin, Gilles Bruylants
Summary: In this study, a thin and robust coating based on calixarene-diazonium salts was developed to maintain the anisotropic structure of silver nanoplates, resulting in increased lifetime and stability. This coated silver nanoplates were then used for the detection of rabbit immunoglobulin G and Anti-SARS-CoV-2 IgG, achieving a low limit of detection and successful detection in human plasma. Additionally, the wide range of colors provided by the silver nanoplates allowed for the design of a multicolor multiplex assay for simultaneous detection of multiple analytes.
Review
Chemistry, Analytical
Anara Molkenova, Hye Eun Choi, Jeong Min Park, Jin-Ho Lee, Ki Su Kim
Summary: Lanthanide-based upconversion nanoparticles (UCNPs) have attracted scientists' attention for their ability to convert tissue-penetrating near-infrared light into tailored optical illumination inside biological matter. These luminescent UCNPs have been widely used for background-free biorecognition and biosensing. Maximizing NIR light harvesting and upconversion efficiencies while protecting biological tissue is a challenge for laser-assisted photoactivation, and this review provides an overview of recent achievements and challenges in plasmon-modulated upconversion nanoformulations for biosensing applications.
Article
Chemistry, Multidisciplinary
Chang Lu, Mohamad Zandieh, Jinkai Zheng, Juewen Liu
Summary: In this study, the effect of DNA adsorption on the seeded growth of AuNPs was investigated. It was found that heating-induced DNA adsorption resulted in more anisotropic nanoparticle growth. This research provides fundamental insights into the control of nanoparticle morphology without changing the DNA sequence.
Article
Chemistry, Multidisciplinary
Liran Tian, Xiangwei Song, Tianjiao Liu, Anfeng Li, Yang Ning, Xiuyi Hua, Deming Dong, Dapeng Liang
Summary: A UV-Visible and fluorescence detection method was designed for the determination of acetamiprid based on the specific identification ability of aptamers. The presence of acetamiprid could be clearly determined through the aggregation of gold nanoparticles and the redshifting of the UV-vis absorption peak. This combined method showed a wide detection range and a low detection limit, making it a potential simple method for the determination of acetamiprid residues in natural water bodies.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Claudia Borri, Sonia Centi, Sofia Chioccioli, Patrizia Bogani, Filippo Micheletti, Marco Gai, Paolo Grandi, Serena Laschi, Francesco Tona, Andrea Barucci, Nicola Zoppetti, Roberto Pini, Fulvio Ratto
Summary: Paper-based biosensors have gained momentum in the field of rapid antigen testing for SARS-CoV-2. This paper proposes a revision of the current format by utilizing advances in materials science and data processing. By using gold nanorods and improving the workflow, the speed and sensitivity of the biosensors can be enhanced.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
Lixian Huang, Jinling Zhang, Lifang Pang, Shengqiang Hu, Liangliang Zhang, Shulin Zhao
Summary: By controlling the melting temperature-dependent assembly-disassembly of pSNAs, a temperature-self-controllable and biomarker-activatable photothermal effect in vivo was achieved.
CHEMICAL COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Clarissa L. M. Hofmann, Stefan Fischer, Emil H. Eriksen, Benedikt Blaesi, Christian Reitz, Deniz Yazicioglu, Ian A. Howard, Bryce S. Richards, Jan Christoph Goldschmidt
Summary: An experimental validation of the effects of photonic structures on upconversion, and the proposal of a theoretical model to describe these effects, have opened up new possibilities for optimizing photonic structure designs.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Xianli Chen, Yong Liang
Summary: A differential colorimetric sensor array was developed for the simultaneous and accurate identification of nine proteins, showing promising potential for early disease diagnostics.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Erik Dimitrov, Natalia Toncheva-Moncheva, Pavel Bakardzhiev, Aleksander Forys, Jordan Doumanov, Kirilka Mladenova, Svetla Petrova, Barbara Trzebicka, Stanislav Rangelov
Summary: This article introduces the construction and characteristics of vesicular spherical nucleic acids, which have promising applications as drug and nucleic acid delivery materials, diagnostic and imaging tools, and platforms for therapeutic scheme development. The study shows that vesicular structures have the ability to spontaneously internalize into cells, enhanced colloidal and nuclease stability.
NANOSCALE ADVANCES
(2022)
Article
Chemistry, Multidisciplinary
Emma E. Coughlin, Jingtian Hu, Andrew Lee, Teri W. Odom
Summary: This paper demonstrates the light-directed functionalization of anisotropic gold nanoparticles with different thiolated-DNA oligomer sequences, enabling the creation of nanoparticle superstructures with precise control over oligo presentation at the single-particle level.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Analytical
Qiujun Lu, Lingling Xie, Shuhang Yin, Feng Chen, Cuiyan Wu, Meiling Liu, Haitao Li, Youyu Zhang
Summary: A novel luminescent nanosensor for ultrasensitive detection of miRNA-10b has been developed, which shows great promise for early diagnosis of hepatocellular carcinoma (HCC) due to its high sensitivity and selectivity.
Review
Chemistry, Multidisciplinary
Yi Wei, Wei Wang, Zhennan Wang, Hang Yang, Xinyu You, Yunna Zhao, Peipei Dang, Hongzhou Lian, Jianhua Hao, Guogang Li, Jun Lin
Summary: This review highlights the applications and properties of Bi3+-included lead-free metal halide materials in the field of optoelectronics, with a focus on the role and impact of Bi3+ ions in LFMH materials.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biophysics
Menglin Song, Man-Chung Wong, Lihua Li, Feng Guo, Yuan Liu, Yingjing Ma, Xinyue Lao, Pui Wang, Honglin Chen, Mo Yang, Jianhua Hao
Summary: We have developed a point-of-care upconversion luminescence diagnostics (PULD) method combined with a streamlined smartphone-based portable platform for rapid testing of the SARS-CoV-2 nucleocapsid (N) gene. This method demonstrates high sensitivity and signal-to-noise ratio, and can accurately identify positive COVID-19 samples.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Multidisciplinary Sciences
Qingyi Zhang, Ning Li, Tao Zhang, Dianmeng Dong, Yongtao Yang, Yuehui Wang, Zhengang Dong, Jiaying Shen, Tianhong Zhou, Yuanlin Liang, Weihua Tang, Zhenping Wu, Yang Zhang, Jianhua Hao
Summary: By lattice and band engineering, Zhang et al. constructed a unipolar barrier avalanche photodiode with suppressed dark current and reinforced reverse breakdown. Ga2O3-based solar blind avalanche photodetectors exhibit low voltage operation, optical filter-free and monolithic integration of photodetector arrays, and therefore they are promising to be an alternative to the bulky and fragile photomultiplier tubes for weak signal detection in deep-ultraviolet region. These findings provide insights into precise manipulation of band alignment in avalanche photodetectors, and also offer exciting opportunities for further developing high-performance Ga2O3-based electronics and optoelectronics.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Shuo Shi, Yifan Si, Zihua Li, Shuo Meng, Shuai Zhang, Hanbai Wu, Chuanwei Zhi, Weng-Fu Io, Yang Ming, Dong Wang, Bin Fei, Haitao Huang, Jianhua Hao, Jinlian Hu
Summary: Developing intelligent wearable protection systems is highly important for human health engineering. We have developed an intelligent wearable filtration system (IWFS) using advanced nanotechnology and machine learning, which exhibits reliable filtration efficiency, low pressure drop, healthcare monitoring function, and man-machine interactive capability. The IWFS has a high particle filtration efficiency of 99%, bacteria protection efficiency of 100%, and low-pressure drop of 5.8 mmH2O. It also possesses healthcare monitoring function and man-machine interactive capability, enabling real-time data collection and voice command transmission.
Article
Physics, Applied
Yuqian Zhao, Feng Guo, Sin-Yi Pang, Weng Fu Io, Lok-Wing Wong, Jiong Zhao, Jianhua Hao
Summary: The anisotropic Raman response of ultrathin black phosphorus (BP) transferred to an oxide dielectric substrate is investigated by utilizing a piezoelectric actuator to perform biaxial strain engineering. The strained Raman response is related to the variations of bond angle and bond length in BP, and biaxial strain modulation can change the anisotropic dispersion of BP.
APPLIED PHYSICS LETTERS
(2023)
Article
Nanoscience & Nanotechnology
Lihua Li, Zefeng Lin, Xingyi Xu, Wanshun Wang, Hu Chen, Zhibin Feng, Zhongmin Yang, Jianhua Hao
Summary: Nanozymes have been developed for disease theranostics, and in this study, BDS-GOx@MnOx nanozymes based on a bismuth-manganese core-shell nanoflower were designed for tumor theranostics. These nanozymes showed enhanced starvation treatment and chemotherapy efficacy, and could also be used for tumor-enhanced CT and MR imaging. The characterization and mechanism of the BDS-GOx@MnOx nanozymes were systematically studied and revealed.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Hanbai Wu, Shuo Shi, Huiqun Zhou, Chuanwei Zhi, Shuo Meng, Weng-Fu Io, Yang Ming, Yuchao Wang, Leqi Lei, Bin Fei, Jianhua Hao, Jinlian Hu
Summary: This study utilized electrospinning technology to fabricate bone-mimicking microenvironments and demonstrated that stem cells can autonomously regulate their differentiation by remodeling the cytoskeleton. Aligned and random nanofibers had different effects on the osteogenic ability and calcium activity of stem cells, with random nanofibers showing better osteogenesis.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Editorial Material
Physics, Applied
Hong Wang, Jianhua Hao, Qing Wang
Summary: Functional dielectrics are materials with interesting electro-active behaviors, such as variable permittivity, high breakdown strength, ferroelectricity, piezoelectricity, and pyroelectricity. They have the ability to generate and respond to electric fields in a nonlinear manner, making them highly desirable for energy conversion and storage applications.
APPLIED PHYSICS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Xinyue Lao, Yuan Liu, Lihua Li, Menglin Song, Yingjin Ma, Mo Yang, Guanying Chen, Jianhua Hao
Summary: This study presents an ultrasensitive biosensor based on core-shell upconversion nanoparticles and gold nanoparticles for accurate detection of SARS-CoV-2 viral RNA. The integration of FRET and surface plasmon greatly enhances the sensitivity of the biosensor, which has been validated using clinical samples.
Article
Materials Science, Multidisciplinary
Tianqi Zhang, Fangqing Zhao, Pai Liu, Yangzhi Tan, Xiangtian Xiao, Zhaojin Wang, Weigao Wang, Dan Wu, Xiao Wei Sun, Jianhua Hao, Guichuan Xing, Kai Wang
Summary: The mechanism of electron leakage in green InP quantum-dot light-emitting diodes is revealed. An ultrathin LiF layer is introduced to modify the work function of indium tin oxide, which simultaneously hinders the electron leakage and enhances the hole injection.
ADVANCED PHOTONICS RESEARCH
(2023)
Review
Chemistry, Physical
Xiao Han, Xueyuan Qiu, Meng Zong, Jianhua Hao
Summary: As an emerging family of 2D nanomaterials, early transition metal carbides and carbonitrides (MXenes) have shown great potential in various applications. Research on MXene-based polymer nanocomposites has gained increasing attention due to their improved oxidation and damage tolerance. MXenes can enhance the mechanical properties and provide desired thermal/electrical properties to polymer. The assembly of MXene nanosheets into MXene macrostructures (MMs) is an effective strategy to optimize the performance of the nanocomposites. This review summarizes recent research progress on MMs/polymer nanocomposites, focusing on the relationships among structures, fabrication techniques, and performance. It also discusses the applications of these nanocomposites in heat/electrical conduction, electromagnetic shielding, and flexible devices. Challenges and future perspectives for multifunctional MMs/polymer nanocomposites are also highlighted.
Article
Chemistry, Multidisciplinary
Huan Duan, Dehui Wang, Jingxi Gou, Feng Guo, Wenjing Jie, Jianhua Hao
Summary: This study fabricates two-terminal memristors based on two-dimensional MoSe2 nanosheets, which exhibit analog resistive switching (RS) behaviors and can simulate the synaptic plasticity of the human brain. The fabricated memristors successfully implement synaptic functions and achieve a high recognition accuracy of 92% in image recognition tasks. They can also emulate the learning-forgetting experience of the human brain and recognize noxious stimuli as artificial nociceptors. This research provides comprehensive investigations and promising prospects for neuromorphic computing based on 2D MoSe2 nanosheets.
Article
Chemistry, Multidisciplinary
Shuo Shi, Yifan Si, Zihua Li, Shuo Meng, Shuai Zhang, Hanbai Wu, Chuanwei Zhi, Weng-Fu Io, Yang Ming, Dong Wang, Bin Fei, Haitao Huang, Jianhua Hao, Jinlian Hu
Summary: Developing intelligent wearable protection systems is highly important for human health engineering. In this study, an intelligent wearable filtration system (IWFS) was developed using advanced nanotechnology and machine learning. The IWFS exhibited high particle filtration efficiency, low pressure drop, and healthcare monitoring function, along with man-machine interactive capability.
Correction
Materials Science, Biomaterials
Zhigao Yi, Xiaolong Li, Wei Lu, Hongrong Liu, Songjun Zeng, Jianhua Hao
Summary: This article introduces a method using hybrid lanthanide nanoparticles as contrast agents to achieve T-1/T-2 dual-weighted MRI and synergistic tumor diagnosis.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Qin Zhang, Bohan Yin, Jianhua Hao, Linjie Ma, Yingying Huang, Xueying Shao, Chuanqi Li, Zhiqin Chu, Changqing Yi, Siu Hong Dexter Wong, Mo Yang
Summary: A highly sequence-specific biosensor based on nanocomposites has been developed for one step-detection of SARS-CoV-2-specific nucleic acid sequences. The method is rapid, inexpensive, and sensitive, with detection completed within 1 hour without amplification.
